Page last updated: 2024-10-26

disulfiram and Head and Neck Neoplasms

disulfiram has been researched along with Head and Neck Neoplasms in 5 studies

Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)

Research Excerpts

ExcerptRelevanceReference
"The cytotoxic effect of DSF/Cu against cervical cancer cell lines in vitro was mediated by apoptosis and autophagy simultaneously."1.72Anti-Cancer Effects of Disulfiram in Cervical Cancer Cell Lines Are Mediated by Both Autophagy and Apoptosis. ( Huang, S; Li, J; Li, L; Li, M; Li, Y; Sun, Z; Yan, Z; Zhai, Q; Zhang, W, 2022)
"Disulfiram has been repurposed as a potential candidate to suppress various cancers."1.62Repurposing disulfiram to induce OSCC cell death by cristae dysfunction promoted autophagy. ( Cai, LY; Chen, QM; Ji, N; Jiang, H; Shen, YQ; Wang, Z; Zeng, X; Zhou, Y, 2021)
"Disulfiram can inhibit EMT of Smad4 mutant and Smad4 non-mutated OSCC cells by blocking ERK phosphorylation in the MAPK signaling pathway."1.56[Effect of disulfiram on epithelial-mesenchymal transformation of oral squamous cell carcinoma cells]. ( Jiang, Y; Wang, XM, 2020)
"The anti-cancer effects of DSF in HNSCC were found to be copper (Cu) dependent."1.48Anti-cancer effects of disulfiram in head and neck squamous cell carcinoma via autophagic cell death. ( Cho, JG; Go, YY; Park, YM; Shin, SH; Song, JJ; Woo, JS, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Zhang, W1
Zhai, Q1
Li, M1
Huang, S1
Sun, Z1
Yan, Z1
Li, J1
Li, L1
Li, Y1
Wang, XM1
Jiang, Y1
Wang, Z1
Jiang, H1
Cai, LY1
Ji, N1
Zeng, X1
Zhou, Y1
Shen, YQ1
Chen, QM1
Park, YM1
Go, YY1
Shin, SH1
Cho, JG1
Woo, JS1
Song, JJ1
McGregor, NR1

Reviews

1 review available for disulfiram and Head and Neck Neoplasms

ArticleYear
Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk.
    Alcohol (Fayetteville, N.Y.), 2007, Volume: 41, Issue:7

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Aldehyd

2007

Other Studies

4 other studies available for disulfiram and Head and Neck Neoplasms

ArticleYear
Anti-Cancer Effects of Disulfiram in Cervical Cancer Cell Lines Are Mediated by Both Autophagy and Apoptosis.
    Bulletin of experimental biology and medicine, 2022, Volume: 172, Issue:5

    Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Copper; Disulfiram; Female; Head and Neck Neoplasms

2022
[Effect of disulfiram on epithelial-mesenchymal transformation of oral squamous cell carcinoma cells].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2020, Volume: 29, Issue:2

    Topics: Cadherins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Disulfiram; Epithelial-Mesench

2020
Repurposing disulfiram to induce OSCC cell death by cristae dysfunction promoted autophagy.
    Oral diseases, 2021, Volume: 27, Issue:5

    Topics: Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Proliferation; Di

2021
Anti-cancer effects of disulfiram in head and neck squamous cell carcinoma via autophagic cell death.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: Animals; Antineoplastic Agents; Autophagy; Capsid Proteins; Cell Line, Tumor; Copper; Disulfiram; Dr

2018