disulfiram has been researched along with Glial Cell Tumors in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disulfiram (DSF) is an old alcohol-aversion drug that has anti-tumor activities against diverse cancer types such as GBM in preclinical studies, especially when it is combined with cupper ion (Cu)." | 5.62 | Therapeutic effect of disulfiram inclusion complex embedded in hydroxypropyl-β-cyclodextrin on intracranial glioma-bearing male rats via intranasal route. ( Li, C; Ma, D; Ma, L; Ma, W; Qu, Y; Sun, X; Xu, Z; Zhao, Z; Zhou, Y, 2021) |
| "Disulfiram is a drug used to support the treatment of chronic alcoholism and was found to be effective against diverse cancer types in preclinical studies." | 5.62 | Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation. ( Anderson, J; Cantilena, S; de Boer, J; Hargrave, D; Meier, S; Michod, D; Niklison Chirou, MV; Salomoni, P, 2021) |
| "Glioma is the most common of all central nervous system (CNS) malignancies and is associated with a poor prognosis." | 1.72 | Bulk and Single-Cell Transcriptome Analyses Revealed That the Pyroptosis of Glioma-Associated Macrophages Participates in Tumor Progression and Immunosuppression. ( Hua, Z; Li, C; Li, L; Wu, L; Yin, X, 2022) |
| "Disulfiram (DSF) is an old alcohol-aversion drug that has anti-tumor activities against diverse cancer types such as GBM in preclinical studies, especially when it is combined with cupper ion (Cu)." | 1.62 | Therapeutic effect of disulfiram inclusion complex embedded in hydroxypropyl-β-cyclodextrin on intracranial glioma-bearing male rats via intranasal route. ( Li, C; Ma, D; Ma, L; Ma, W; Qu, Y; Sun, X; Xu, Z; Zhao, Z; Zhou, Y, 2021) |
| "Disulfiram is a drug used to support the treatment of chronic alcoholism and was found to be effective against diverse cancer types in preclinical studies." | 1.62 | Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation. ( Anderson, J; Cantilena, S; de Boer, J; Hargrave, D; Meier, S; Michod, D; Niklison Chirou, MV; Salomoni, P, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L | 1 |
| Wu, L | 1 |
| Yin, X | 1 |
| Li, C | 2 |
| Hua, Z | 1 |
| Qu, Y | 1 |
| Sun, X | 1 |
| Ma, L | 1 |
| Xu, Z | 1 |
| Ma, W | 1 |
| Zhou, Y | 1 |
| Zhao, Z | 1 |
| Ma, D | 1 |
| Meier, S | 1 |
| Cantilena, S | 1 |
| Niklison Chirou, MV | 1 |
| Anderson, J | 1 |
| Hargrave, D | 1 |
| Salomoni, P | 1 |
| de Boer, J | 1 |
| Michod, D | 1 |
| Li, Y | 1 |
| Fu, SY | 1 |
| Wang, LH | 1 |
| Wang, FY | 1 |
| Wang, NN | 1 |
| Cao, Q | 1 |
| Wang, YT | 1 |
| Yang, JY | 1 |
| Wu, CF | 1 |
| Marikovsky, M | 1 |
| Nevo, N | 1 |
| Vadai, E | 1 |
| Harris-Cerruti, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Phase 2 Trial of Treatment of Advanced Non Small Cell Lung Carcinoma With/Without Disulfiram and Cisplatin Navelbine[NCT00312819] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2006-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for disulfiram and Glial Cell Tumors
| Article | Year |
|---|---|
Bulk and Single-Cell Transcriptome Analyses Revealed That the Pyroptosis of Glioma-Associated Macrophages Participates in Tumor Progression and Immunosuppression.
Topics: Disulfiram; Gene Expression Profiling; Glioma; Humans; Immunosuppression Therapy; Lipopolysaccharide | 2022 |
Therapeutic effect of disulfiram inclusion complex embedded in hydroxypropyl-β-cyclodextrin on intracranial glioma-bearing male rats via intranasal route.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Intranasal; Animals; Disulfiram; Glioma; Male; Ra | 2021 |
Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation.
Topics: Alcoholism; Auranofin; Cell Line, Tumor; Cell Proliferation; Child; Disulfiram; Down-Regulation; Dru | 2021 |
Copper improves the anti-angiogenic activity of disulfiram through the EGFR/Src/VEGF pathway in gliomas.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; | 2015 |
Cu/Zn superoxide dismutase plays a role in angiogenesis.
Topics: Animals; Apoptosis; Brain Neoplasms; Carcinoma, Lewis Lung; Disulfiram; Endothelium, Vascular; Enzym | 2002 |