disulfiram has been researched along with Experimental Neoplasms in 33 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to determine if disulfiram would influence the induction of urinary bladder cancer in rats given N-n-butyl-N(4-hydroxybuty)nitrosamine (BHBN)." | 7.66 | Inhibition of N-n-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in rats by administration of disulfiram in the diet. ( Irving, CC; Murphy, WM; Tice, AJ, 1979) |
| " The objective of this study was to determine if disulfiram would inhibit the induction of bladder cancer in rats given BCPN, as reported for BHBN (Cancer Res." | 3.66 | The effect of disulfiram on the carcinogenicity of N-butyl-N-(3-carboxypropyl)nitrosamine in the rat. ( Daniel, DS; Irving, CC; Murphy, WM, 1983) |
| "The objective of this study was to determine if disulfiram would influence the induction of urinary bladder cancer in rats given N-n-butyl-N(4-hydroxybuty)nitrosamine (BHBN)." | 3.66 | Inhibition of N-n-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in rats by administration of disulfiram in the diet. ( Irving, CC; Murphy, WM; Tice, AJ, 1979) |
| " Thus, neither DSF nor DDTC impaired the antitumour effect of IFX and both diminished its adverse effects." | 1.28 | Drug interaction effects on antitumour drugs (VIII): prevention of ifosfamide-induced urotoxicity by disulfiram and its effect on antitumour activity and acute toxicity of alkylating agents in mice. ( Ishikawa, M; Sasaki, K; Takayanagi, Y, 1991) |
| " DENA, which was administered to 38 rats in a dosage of 20 mg/kg/week, induced liver tumors in 90% of the animals; in 29% besides some precancerous stages predominantly malignant carcinomas of the oesophagus were seen." | 1.26 | Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats. ( Diehl, B; Habs, M; Krüger, FW; Schmähl, D, 1976) |
| " Pharmacokinetic parameters and enzyme kinetic data both in normal and in tumor-bearing animals will be presented." | 1.26 | Importance of pharmacokinetic studies on cyclophosphamide (NSC-26271) in understanding its cytotoxic effect. ( Bartosek, I; Colombo, T; Donelli, MG; Guaitani, A; Martini, A; Modica, R; Pacciarini, MA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (84.85) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 1 (3.03) | 29.6817 |
| 2010's | 1 (3.03) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Popović, KJ | 1 |
| Popović, DJ | 1 |
| Miljković, D | 1 |
| Popović, JK | 1 |
| Lalošević, D | 1 |
| Poša, M | 1 |
| Čapo, I | 1 |
| Hassan, I | 1 |
| Khan, AA | 1 |
| Aman, S | 1 |
| Qamar, W | 1 |
| Ebaid, H | 1 |
| Al-Tamimi, J | 1 |
| Alhazza, IM | 1 |
| Rady, AM | 1 |
| Brar, SS | 1 |
| Grigg, C | 1 |
| Wilson, KS | 1 |
| Holder, WD | 1 |
| Dreau, D | 1 |
| Austin, C | 1 |
| Foster, M | 1 |
| Ghio, AJ | 1 |
| Whorton, AR | 1 |
| Stowell, GW | 1 |
| Whittall, LB | 1 |
| Whittle, RR | 1 |
| White, DP | 1 |
| Kennedy, TP | 1 |
| Epstein, SS | 1 |
| Joshi, S | 1 |
| Andrea, J | 1 |
| Forsyth, J | 1 |
| Mantel, N | 1 |
| Irving, CC | 2 |
| Daniel, DS | 1 |
| Murphy, WM | 2 |
| Griffin, AC | 1 |
| Elliott, BM | 1 |
| Ashby, J | 1 |
| Wong, LC | 1 |
| Winston, JM | 1 |
| Hong, CB | 1 |
| Plotnick, H | 1 |
| Schweinsberg, F | 2 |
| Weissenberger, I | 1 |
| Burkle, V | 2 |
| Fiala, ES | 1 |
| Weisburger, JH | 1 |
| Katayama, S | 1 |
| Chandrasekaran, V | 1 |
| Williams, GM | 1 |
| Lijinsky, W | 1 |
| Reuber, MD | 1 |
| Pumo, DE | 1 |
| Gootnick, D | 1 |
| Little, BW | 1 |
| Chiu, JF | 1 |
| Habs, M | 2 |
| Schmähl, D | 2 |
| Kretzer, H | 1 |
| Krüger, FW | 1 |
| Diehl, B | 1 |
| Moriya, M | 1 |
| Ohta, T | 1 |
| Watanabe, K | 1 |
| Watanabe, Y | 1 |
| Sugiyama, F | 1 |
| Miyazawa, T | 1 |
| Shirasu, Y | 1 |
| Wattenberg, LW | 4 |
| Tice, AJ | 1 |
| Black, HS | 1 |
| Chan, JT | 1 |
| Brown, GE | 1 |
| Nigro, ND | 1 |
| Campbell, RL | 1 |
| Borchert, P | 1 |
| Donelli, MG | 1 |
| Bartosek, I | 1 |
| Guaitani, A | 1 |
| Martini, A | 1 |
| Colombo, T | 1 |
| Pacciarini, MA | 1 |
| Modica, R | 1 |
| Ishikawa, M | 1 |
| Takayanagi, Y | 1 |
| Sasaki, K | 1 |
| Mashiba, H | 1 |
| Matsunaga, K | 1 |
| Rao, AR | 1 |
| Hussain, SP | 1 |
| Jannu, L | 1 |
| Bodenner, DL | 1 |
| Dedon, PC | 1 |
| Keng, PC | 1 |
| Katz, JC | 1 |
| Borch, RF | 1 |
| Pötzsch, J | 1 |
| Schramm, T | 2 |
| Schuhmacher, J | 2 |
| Scherf, HR | 2 |
| Bertram, B | 2 |
| Frei, E | 2 |
| Hauser, H | 1 |
| Wiessler, M | 2 |
| Tacchi, AM | 1 |
| Bender, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Open Labeled Trial of Disulfiram With Copper in Metastatic Breast Cancer[NCT03323346] | Phase 2 | 150 participants (Anticipated) | Interventional | 2017-09-29 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for disulfiram and Experimental Neoplasms
| Article | Year |
|---|---|
Cancer chemoprevention.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Carcinogens; Disulfiram; Drug Therapy; Female; Huma | 1980 |
Inhibition of chemical carcinogenesis.
Topics: Animals; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Disulfiram; Enzyme Inducti | 1978 |
[Chemoprevention of cancer--present status, problems and trends].
Topics: Animals; Antioxidants; Disulfiram; Humans; Neoplasms; Neoplasms, Experimental; Phenols; Retinoids; S | 1987 |
30 other studies available for disulfiram and Experimental Neoplasms
| Article | Year |
|---|---|
Disulfiram and metformin combination anticancer effect reversible partly by antioxidant nitroglycerin and completely by NF-κB activator mebendazole in hamster fibrosarcoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Disulfiram; Female; Fibrosarc | 2021 |
Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Cell Survival; Chemotherapy, Adjuvant; Copper; Disulfiram; Drug Syne | 2018 |
Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Copper; Cyclic AMP Response El | 2004 |
The null effect of antioxidants on the carcinogenicity of 3, 4, 9, 10-dibenzpyrene to mice.
Topics: Aniline Compounds; Animals; Antioxidants; Benzopyrenes; Butyrophenones; Carcinogens; Disulfiram; Fib | 1967 |
The effect of disulfiram on the carcinogenicity of N-butyl-N-(3-carboxypropyl)nitrosamine in the rat.
Topics: Animals; Body Weight; Carcinogens; Disulfiram; Male; Neoplasms, Experimental; Nitrosamines; Rats; Ra | 1983 |
Studies on the mechanism of the synergistic carcinogenic response reported between ethylene and disulfiram and the implications for short term predictive screening tests.
Topics: Animals; Carcinogens; Cocarcinogenesis; Disulfiram; Drug Evaluation, Preclinical; Ethylene Dibromide | 1980 |
Carcinogenicity and toxicity of 1,2-dibromoethane in the rat.
Topics: Animals; Blood; Body Weight; Disulfiram; Eating; Ethylene Dibromide; Female; Hydrocarbons, Brominate | 1982 |
The effect of disulfiram on the carcinogenicity of nitrosamines.
Topics: Animals; Disulfiram; Esophagus; Female; Liver; Lung; Neoplasms, Experimental; Nitrosamines; Rats; Ra | 1982 |
The effect of disulfiram on the carcinogenicity of 3,2'dimethyl-4-aminopbiphenyl in Syrian golden hamsters and rats.
Topics: Aminobiphenyl Compounds; Aniline Compounds; Animals; Carcinogens; Cricetinae; Diphenylamine; Disulfi | 1981 |
[Effect of disulfiram on the toxicity and carcinogenicity of N-methyl-n-nitrosobenzylamine in rats (author's transl)].
Topics: Animals; Bronchial Neoplasms; Dimethylnitrosamine; Disulfiram; Drug Synergism; Esophageal Neoplasms; | 1981 |
Tumours induced in Fischer 344 rats by the feeding of disulfiram together with sodium nitrite.
Topics: Animals; Carcinogens; Diet; Diethylnitrosamine; Disulfiram; Drug Interactions; Esophageal Neoplasms; | 1980 |
Colon tumor specific nuclear antigen with potential as a pre-tumor diagnostic probe.
Topics: Animals; Antigens, Neoplasm; Cell Nucleus; Colon; Colonic Neoplasms; Dimethylhydrazines; Disulfiram; | 1980 |
Effect of disulfiram on acetoxymethyl-methyl-nitrosamine-induced tumors in rats.
Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Dimethylnitrosamine; Disulfiram; Ear Neoplasms; F | 1981 |
Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats.
Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Disulfiram; Esophageal Neoplasms; Liver Neoplasms; | 1976 |
Some carbamates, thiocarbamates and carbazides.
Topics: Animals; Azides; Carbamates; Carbaryl; Disulfiram; Ditiocarb; Herbicides; Humans; Insecticides; Mane | 1976 |
Inhibitors for the mutagenicities of colon carcinogens, 1,2-dimethylhydrazine and azoxymethane, in the host-mediated assay.
Topics: Aminoacetonitrile; Animals; Azo Compounds; Azoxymethane; Carbon Disulfide; Colonic Neoplasms; Dimeth | 1979 |
Inhibition of N-n-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in rats by administration of disulfiram in the diet.
Topics: Animals; Biotransformation; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disulfiram; | 1979 |
Effects of dietary constituents on ultraviolet light-mediated carcinogenesis.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Diet; Disulfiram; Female; Glutathione; Keratosis; M | 1978 |
Inhibition of azoxymethane-induced intestinal cancer by disulfiram.
Topics: Animals; Azo Compounds; Azoxymethane; Biotransformation; Colon; Colostomy; Disulfiram; Intestinal Ne | 1978 |
Inhibition of macromolecular binding of benzo(a)pyrene and inhibition of neoplasia by disulfiram in the mouse forestomach.
Topics: Animals; Benzopyrenes; Disulfiram; DNA; Female; Gastric Mucosa; Liver; Mice; Neoplasms, Experimental | 1976 |
Inhibition of dimethylhydrazine-induced neoplasia of the large intestine by disulfiram.
Topics: Animals; Diet; Disulfiram; Female; Hydrazines; Intestinal Neoplasms; Mice; Neoplasms, Experimental | 1975 |
Importance of pharmacokinetic studies on cyclophosphamide (NSC-26271) in understanding its cytotoxic effect.
Topics: Animals; Carcinoma 256, Walker; Chloral Hydrate; Cyclophosphamide; Disulfiram; Drug Interactions; Gl | 1976 |
Drug interaction effects on antitumour drugs (VIII): prevention of ifosfamide-induced urotoxicity by disulfiram and its effect on antitumour activity and acute toxicity of alkylating agents in mice.
Topics: Animals; Disulfiram; Ditiocarb; Dose-Response Relationship, Drug; Ifosfamide; Leukopenia; Male; Mice | 1991 |
Augmented inhibition of tumor cell proliferation in the combined use of disulfiram with ascorbic acid and the involvement of oxygen free radicals.
Topics: Animals; Ascorbic Acid; Carcinoma, Ehrlich Tumor; Catalase; Cell Division; Disulfiram; Free Radicals | 1990 |
Modulation of 7,12-dimethylbenz[a]anthracene-induced transmammary carcinogenesis by disulfiram and butylated hydroxyanisole in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butylated Hydroxyanisole; Disulfiram; Female; Lactation; | 1989 |
Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut, and bone marrow by diethyldithiocarbamate.
Topics: Animals; Blood Cell Count; Blood Urea Nitrogen; Bone Marrow; Cisplatin; Disulfiram; Ditiocarb; Dogs; | 1986 |
Influence of a prolonged treatment with disulfiram and D-penicillamine on nitrosodiethylamine-induced biological and biochemical effects. II. Investigations on trace elements in the liver.
Topics: Animals; Diethylnitrosamine; Disulfiram; Drug Interactions; Liver; Male; Neoplasms, Experimental; Ni | 1985 |
Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system.
Topics: Animals; Diethylnitrosamine; Disulfiram; Drug Interactions; Enzyme Inhibitors; Esophageal Neoplasms; | 1985 |
Inhibition of carcinogenic and toxic effects of polycyclic hydrocarbons by several sulfur-containing compounds.
Topics: Adenoma; Administration, Oral; Adrenal Glands; Aldehyde Oxidoreductases; Animals; Benz(a)Anthracenes | 1974 |
[Further studies of the problem of different thermosensitivity of tumor and normal cells in vitro and in vivo].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Bronchial Neoplasms; Carcinoma, Ehrlich Tumor; Chickens; Cr | 1968 |