Page last updated: 2024-10-26

disulfiram and Esophageal Squamous Cell Carcinoma

disulfiram has been researched along with Esophageal Squamous Cell Carcinoma in 2 studies

Esophageal Squamous Cell Carcinoma: A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.

Research Excerpts

ExcerptRelevanceReference
" We have previously shown that the anti-diabetic drug metformin is anti-proliferative and induces an intracellular reducing environment in oesophageal squamous cell carcinoma (OSCC) cell lines."7.81Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines. ( Birkhead, M; Damelin, LH; Jivan, R; Mavri-Damelin, D; Rousseau, AL; Veale, RB, 2015)
" We have previously shown that the anti-diabetic drug metformin is anti-proliferative and induces an intracellular reducing environment in oesophageal squamous cell carcinoma (OSCC) cell lines."3.81Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines. ( Birkhead, M; Damelin, LH; Jivan, R; Mavri-Damelin, D; Rousseau, AL; Veale, RB, 2015)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Qian, L1
Murakami, K1
Toyozumi, T1
Matsumoto, Y1
Otsuka, R1
Sekino, N1
Endo, S1
Kinoshita, K1
Sasaki, T1
Matsubara, H1
Jivan, R1
Damelin, LH1
Birkhead, M1
Rousseau, AL1
Veale, RB1
Mavri-Damelin, D1

Other Studies

2 other studies available for disulfiram and Esophageal Squamous Cell Carcinoma

ArticleYear
An anti-alcoholism drug, disulfiram and copper complex improves radio-resistance of tumor-initiating cells in esophageal squamous cell carcinoma.
    Esophagus : official journal of the Japan Esophageal Society, 2023, Volume: 20, Issue:1

    Topics: Alcoholism; Aldehyde Dehydrogenase 1 Family; Animals; Copper; Disulfiram; Esophageal Neoplasms; Esop

2023
Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:10

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Copper; Disulfiram; Drug Synergism;

2015