Page last updated: 2024-10-26

disulfiram and Esophageal Neoplasms

disulfiram has been researched along with Esophageal Neoplasms in 7 studies

Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
" We have previously shown that the anti-diabetic drug metformin is anti-proliferative and induces an intracellular reducing environment in oesophageal squamous cell carcinoma (OSCC) cell lines."7.81Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines. ( Birkhead, M; Damelin, LH; Jivan, R; Mavri-Damelin, D; Rousseau, AL; Veale, RB, 2015)
" We have previously shown that the anti-diabetic drug metformin is anti-proliferative and induces an intracellular reducing environment in oesophageal squamous cell carcinoma (OSCC) cell lines."3.81Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines. ( Birkhead, M; Damelin, LH; Jivan, R; Mavri-Damelin, D; Rousseau, AL; Veale, RB, 2015)
"Oesophageal squamous cell carcinoma (OSCC) is highly prevalent in developing countries but there has been little recent progress into efficacious yet affordable treatment strategies."1.48Disulfiram with or without metformin inhibits oesophageal squamous cell carcinoma in vivo. ( Damelin, LH; Jivan, R; Mavri-Damelin, D; Peres, J; Prince, S; Veale, RB; Wadee, R, 2018)
" DENA, which was administered to 38 rats in a dosage of 20 mg/kg/week, induced liver tumors in 90% of the animals; in 29% besides some precancerous stages predominantly malignant carcinomas of the oesophagus were seen."1.26Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats. ( Diehl, B; Habs, M; Krüger, FW; Schmähl, D, 1976)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Qian, L1
Murakami, K1
Toyozumi, T1
Matsumoto, Y1
Otsuka, R1
Sekino, N1
Endo, S1
Kinoshita, K1
Sasaki, T1
Matsubara, H1
Jivan, R2
Peres, J1
Damelin, LH2
Wadee, R1
Veale, RB2
Prince, S1
Mavri-Damelin, D2
Birkhead, M1
Rousseau, AL1
Schweinsberg, F1
Bürkle, V1
Lijinsky, W1
Reuber, MD1
Schmähl, D1
Krüger, FW1
Habs, M1
Diehl, B1
Bertram, B1
Frei, E1
Scherf, HR1
Schuhmacher, J1
Tacchi, AM1
Wiessler, M1

Other Studies

7 other studies available for disulfiram and Esophageal Neoplasms

ArticleYear
An anti-alcoholism drug, disulfiram and copper complex improves radio-resistance of tumor-initiating cells in esophageal squamous cell carcinoma.
    Esophagus : official journal of the Japan Esophageal Society, 2023, Volume: 20, Issue:1

    Topics: Alcoholism; Aldehyde Dehydrogenase 1 Family; Animals; Copper; Disulfiram; Esophageal Neoplasms; Esop

2023
Disulfiram with or without metformin inhibits oesophageal squamous cell carcinoma in vivo.
    Cancer letters, 2018, 03-28, Volume: 417

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Carcinoma, Squamous Cell; Cell L

2018
Disulfiram/copper-disulfiram Damages Multiple Protein Degradation and Turnover Pathways and Cytotoxicity is Enhanced by Metformin in Oesophageal Squamous Cell Carcinoma Cell Lines.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:10

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Copper; Disulfiram; Drug Synergism;

2015
[Effect of disulfiram on the toxicity and carcinogenicity of N-methyl-n-nitrosobenzylamine in rats (author's transl)].
    Journal of cancer research and clinical oncology, 1981, Volume: 102, Issue:1

    Topics: Animals; Bronchial Neoplasms; Dimethylnitrosamine; Disulfiram; Drug Synergism; Esophageal Neoplasms;

1981
Tumours induced in Fischer 344 rats by the feeding of disulfiram together with sodium nitrite.
    Food and cosmetics toxicology, 1980, Volume: 18, Issue:1

    Topics: Animals; Carcinogens; Diet; Diethylnitrosamine; Disulfiram; Drug Interactions; Esophageal Neoplasms;

1980
Influence of disulfiram on the organotropy of the carcinogenic effect of dimethylnitrosamine and diethylnitrosamine in rats.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Mar-19, Volume: 85, Issue:3

    Topics: Animals; Diethylnitrosamine; Dimethylnitrosamine; Disulfiram; Esophageal Neoplasms; Liver Neoplasms;

1976
Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system.
    Journal of cancer research and clinical oncology, 1985, Volume: 109, Issue:1

    Topics: Animals; Diethylnitrosamine; Disulfiram; Drug Interactions; Enzyme Inhibitors; Esophageal Neoplasms;

1985