Page last updated: 2024-10-26

disulfiram and Depressive Disorder, Major

disulfiram has been researched along with Depressive Disorder, Major in 4 studies

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research Excerpts

ExcerptRelevanceReference
"Although disulfiram and naltrexone have been approved by the Food and Drug Administration for the treatment of alcoholism, no medications have been approved for individuals with alcohol dependence and comorbid psychiatric disorders."5.12Naltrexone and disulfiram in patients with alcohol dependence and current depression. ( Carroll, K; Levinson, C; Nich, C; Petrakis, I; Poling, J; Ralevski, E; Rounsaville, B, 2007)
"Anxiety is common among persons with alcohol use disorder during early abstinence from alcohol."2.82Coadministration of disulfiram and lorazepam in the treatment of alcohol dependence and co-occurring anxiety disorder: an open-label pilot study. ( Bhatt, S; Bogenschutz, MP; Bohan, J; Foster, B; Romo, P; Tonigan, JS; Wilcox, CE, 2016)
"2."1.51Dispensing of medication for alcohol use disorder; an examination of large databases in a New Zealand context. ( Beaglehole, B; Boden, JM; Foulds, J; Mulder, RT, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beaglehole, B1
Foulds, J1
Mulder, RT1
Boden, JM1
Helton, SG1
Lohoff, FW1
Bogenschutz, MP1
Bhatt, S1
Bohan, J1
Foster, B1
Romo, P1
Wilcox, CE1
Tonigan, JS1
Petrakis, I1
Ralevski, E1
Nich, C1
Levinson, C1
Carroll, K1
Poling, J1
Rounsaville, B1

Reviews

1 review available for disulfiram and Depressive Disorder, Major

ArticleYear
Pharmacogenetics of alcohol use disorders and comorbid psychiatric disorders.
    Psychiatry research, 2015, Dec-15, Volume: 230, Issue:2

    Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Anxiety Disorders; Comorbidity; Depressi

2015

Trials

2 trials available for disulfiram and Depressive Disorder, Major

ArticleYear
Coadministration of disulfiram and lorazepam in the treatment of alcohol dependence and co-occurring anxiety disorder: an open-label pilot study.
    The American journal of drug and alcohol abuse, 2016, Volume: 42, Issue:5

    Topics: Adult; Alcoholism; Anxiety Disorders; Craving; Depressive Disorder, Major; Disulfiram; Drug Therapy,

2016
Naltrexone and disulfiram in patients with alcohol dependence and current depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Alcohol Deterrents; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Comorbidity; Connecticu

2007

Other Studies

1 other study available for disulfiram and Depressive Disorder, Major

ArticleYear
Dispensing of medication for alcohol use disorder; an examination of large databases in a New Zealand context.
    The New Zealand medical journal, 2019, 05-17, Volume: 132, Issue:1495

    Topics: Alcohol Deterrents; Alcoholism; Antidepressive Agents; Depressive Disorder, Major; Disulfiram; Femal

2019