disulfiram has been researched along with Colitis, Ulcerative in 4 studies
Colitis, Ulcerative: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxidative stress, cell pyroptosis and inflammation are considered as important pathogenic factors for ulcerative colitis (UC) development, and the traditional anti-alcoholism drug disulfiram (DSF) has recently been reported to exert its regulating effects on all the above cellular functions, which makes DSF as ideal therapeutic agent for UC treatment, but this issue has not been fully studied." | 8.12 | The anti-alcoholism drug disulfiram effectively ameliorates ulcerative colitis through suppressing oxidative stresses-associated pyroptotic cell death and cellular inflammation in colonic cells. ( Chi, F; Du, F; Li, R; Lin, Z; Ren, N; Shi, X; Zhang, C; Zhang, G; Zhang, J; Zheng, X; Zhu, Y, 2022) |
| " The effect of disulfiram and A-64077 on leukotriene B4 biosynthesis was investigated using human polymorphonuclear leukocyte preparations and an in vivo rat pleurisy assay." | 7.68 | Inhibition of leukotriene B4 biosynthesis by disulfiram and A-64077 during carrageenan-induced pleurisy in the rat. ( Chan, CC; Foster, A; Guay, J; Riendeau, D; Wolfe, S, 1991) |
| "Oxidative stress, cell pyroptosis and inflammation are considered as important pathogenic factors for ulcerative colitis (UC) development, and the traditional anti-alcoholism drug disulfiram (DSF) has recently been reported to exert its regulating effects on all the above cellular functions, which makes DSF as ideal therapeutic agent for UC treatment, but this issue has not been fully studied." | 4.12 | The anti-alcoholism drug disulfiram effectively ameliorates ulcerative colitis through suppressing oxidative stresses-associated pyroptotic cell death and cellular inflammation in colonic cells. ( Chi, F; Du, F; Li, R; Lin, Z; Ren, N; Shi, X; Zhang, C; Zhang, G; Zhang, J; Zheng, X; Zhu, Y, 2022) |
| " The effect of disulfiram and A-64077 on leukotriene B4 biosynthesis was investigated using human polymorphonuclear leukocyte preparations and an in vivo rat pleurisy assay." | 3.68 | Inhibition of leukotriene B4 biosynthesis by disulfiram and A-64077 during carrageenan-induced pleurisy in the rat. ( Chan, CC; Foster, A; Guay, J; Riendeau, D; Wolfe, S, 1991) |
| "Lactoferrin (LF) is a multifunctional glycoprotein with potent antibacterial and anti-inflammatory activities that acts by neutralizing circulating endotoxins and activating cellular responses." | 1.62 | Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases. ( Fang, YF; Huang, YZ; Ou, AT; Tang, XP; Wang, R; Zhang, JX; Zhang, M; Zhao, PF; Zhao, YG, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ou, AT | 1 |
| Zhang, JX | 1 |
| Fang, YF | 1 |
| Wang, R | 1 |
| Tang, XP | 1 |
| Zhao, PF | 1 |
| Zhao, YG | 1 |
| Zhang, M | 1 |
| Huang, YZ | 1 |
| Chi, F | 1 |
| Zhang, G | 1 |
| Ren, N | 1 |
| Zhang, J | 1 |
| Du, F | 1 |
| Zheng, X | 1 |
| Zhang, C | 1 |
| Lin, Z | 1 |
| Li, R | 1 |
| Shi, X | 1 |
| Zhu, Y | 1 |
| Zhou, W | 1 |
| Zhang, H | 1 |
| Huang, L | 1 |
| Sun, C | 1 |
| Yue, Y | 1 |
| Cao, X | 1 |
| Jia, H | 1 |
| Wang, C | 1 |
| Gao, Y | 1 |
| Riendeau, D | 1 |
| Guay, J | 1 |
| Foster, A | 1 |
| Wolfe, S | 1 |
| Chan, CC | 1 |
4 other studies available for disulfiram and Colitis, Ulcerative
| Article | Year |
|---|---|
Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases.
Topics: Acetaldehyde Dehydrogenase Inhibitors; Animals; Anti-Inflammatory Agents; Biomimetic Materials; Coli | 2021 |
The anti-alcoholism drug disulfiram effectively ameliorates ulcerative colitis through suppressing oxidative stresses-associated pyroptotic cell death and cellular inflammation in colonic cells.
Topics: Animals; Caco-2 Cells; Colitis, Ulcerative; Dextran Sulfate; Disulfiram; Glycogen Synthase Kinase 3 | 2022 |
Disulfiram with Cu
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Mod | 2023 |
Inhibition of leukotriene B4 biosynthesis by disulfiram and A-64077 during carrageenan-induced pleurisy in the rat.
Topics: Aldehyde Dehydrogenase; Animals; Carrageenan; Colitis, Ulcerative; Disulfiram; Exudates and Transuda | 1991 |