disulfiram has been researched along with Chronic Disease in 22 studies
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the current study, by utilizing a small molecule covalent compounds library screening, we found that disulfiram (DSF), an FDA-approved chronic alcoholism drug, is a potent DJ-1 inhibitor." | 8.12 | Identifying chronic alcoholism drug disulfiram as a potent DJ-1 inhibitor for cancer therapeutics. ( Cao, J; He, P; He, Q; Jiang, L; Wen, Y; Wu, Q; Yang, B; Yuan, M; Zhang, M, 2022) |
| "Disulfiram is an effective therapeutic agent in the treatment of chronic alcoholism as long as certain conditions are maintained; the patient realises that he is ill, the patient is motivated to be treated and that alcohol withdrawal be maintained chiefly during the first year where there is periodic uneasiness." | 7.65 | [Evaluation of disulfiram treatment in chronic alcoholism]. ( Acke, J, 1975) |
| " In the current study, by utilizing a small molecule covalent compounds library screening, we found that disulfiram (DSF), an FDA-approved chronic alcoholism drug, is a potent DJ-1 inhibitor." | 4.12 | Identifying chronic alcoholism drug disulfiram as a potent DJ-1 inhibitor for cancer therapeutics. ( Cao, J; He, P; He, Q; Jiang, L; Wen, Y; Wu, Q; Yang, B; Yuan, M; Zhang, M, 2022) |
| "Disulfiram is an effective therapeutic agent in the treatment of chronic alcoholism as long as certain conditions are maintained; the patient realises that he is ill, the patient is motivated to be treated and that alcohol withdrawal be maintained chiefly during the first year where there is periodic uneasiness." | 3.65 | [Evaluation of disulfiram treatment in chronic alcoholism]. ( Acke, J, 1975) |
| "Alcohol dependence is a chronic condition impacting millions of individuals worldwide." | 3.30 | Low rates of prescribing alcohol relapse prevention medicines in Australian Aboriginal Community Controlled Health Services. ( Conigrave, JH; Conigrave, KM; Lee, KSK; Purcell-Khodr, G; Vnuk, J, 2023) |
| "Alcohol appears to interact with many drugs in many different and complicated ways." | 1.26 | [Alcohol and drug interactions]. ( Mombelli, G, 1978) |
| "Following chronic administration of disulfiram to rats, changes of the brain were examined electron-microscopically." | 1.26 | Electron microscopic studies on the cerebral lesions of rats in experimental chronic disulfiram poisoning. ( Fujieda, T; Miyagishi, T; Takahata, N; Ueno, T, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, Q | 1 |
| Zhang, M | 1 |
| Wen, Y | 1 |
| He, P | 1 |
| He, Q | 1 |
| Yang, B | 1 |
| Jiang, L | 1 |
| Yuan, M | 1 |
| Cao, J | 1 |
| Purcell-Khodr, G | 1 |
| Conigrave, JH | 1 |
| Lee, KSK | 1 |
| Vnuk, J | 1 |
| Conigrave, KM | 1 |
| Frankl, S | 1 |
| Hadar, PN | 1 |
| Yakhkind, A | 1 |
| Lang, AE | 1 |
| Sandsmark, DK | 1 |
| Kalabukha, VA | 1 |
| Kalabukha, AV | 1 |
| De Sèze, J | 1 |
| Caparros-Lefebvre, D | 1 |
| Nkenjuo, JB | 1 |
| Hurtevent, JF | 1 |
| Petit, H | 1 |
| Kick, SD | 1 |
| Kissin, B | 2 |
| Mombelli, G | 1 |
| Bueno, F | 1 |
| Mezey, E | 1 |
| Sytinsky, IA | 1 |
| Gurevitch, ZP | 1 |
| Ueno, T | 1 |
| Miyagishi, T | 1 |
| Takahata, N | 1 |
| Fujieda, T | 1 |
| Fructuoso, PA | 1 |
| Kolenda, KD | 1 |
| Acke, J | 1 |
| Gross, MM | 1 |
| Feuerlein, W | 1 |
| Kaskevich, LM | 1 |
| Bezuglyĭ, VP | 1 |
| Rosenberg, CM | 1 |
| Gorecki, T | 1 |
| Konarska, L | 1 |
| Ewing, JA | 1 |
| Reimer, F | 1 |
| Pilipenko, VZ | 1 |
| Chistov, AG | 1 |
| Trubinkov, AM | 1 |
2 reviews available for disulfiram and Chronic Disease
| Article | Year |
|---|---|
Modern methods in treatment of chronic alcoholism: a review of the Soviet literature.
Topics: Alcoholism; Aversive Therapy; Chronic Disease; Conditioning, Classical; Disulfiram; Electronarcosis; | 1976 |
[Chronic alcoholism. Development conditions and therapy].
Topics: Alcohol Oxidoreductases; Alcoholism; Autogenic Training; Chlormethiazole; Chronic Disease; Condition | 1972 |
2 trials available for disulfiram and Chronic Disease
| Article | Year |
|---|---|
Low rates of prescribing alcohol relapse prevention medicines in Australian Aboriginal Community Controlled Health Services.
Topics: Acamprosate; Adult; Alcoholism; Australia; Australian Aboriginal and Torres Strait Islander Peoples; | 2023 |
Drug maintenance in the outpatient treatment of chronic alcoholism.
Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Automobile Driving; Boston; Chlordiazep | 1974 |
18 other studies available for disulfiram and Chronic Disease
| Article | Year |
|---|---|
Identifying chronic alcoholism drug disulfiram as a potent DJ-1 inhibitor for cancer therapeutics.
Topics: Alcohol Deterrents; Alcoholism; Antineoplastic Agents; Cell Line, Tumor; Chronic Disease; Copper; Di | 2022 |
Devastating Neurological Injury as a Result of Treatment of "Chronic Lyme Disease".
Topics: Acetaldehyde Dehydrogenase Inhibitors; Acidosis; Anti-Bacterial Agents; Brain; Chronic Disease; Clin | 2021 |
[Use of teturam in treating chronic alcoholism in pulmonary tuberculosis patients].
Topics: Adult; Alcoholism; Chronic Disease; Disulfiram; Drug Evaluation; Female; Humans; Male; Middle Aged; | 1983 |
[Acute and reversible myoclonic encephalopathy, extrapyramidal syndrome, polyneuropathy caused by chronic disulfiram poisoning].
Topics: Acute Disease; Adult; Alcohol Deterrents; Basal Ganglia Diseases; Chronic Disease; Disulfiram; Femal | 1995 |
Evaluation and management of chronic alcohol abuse.
Topics: Alcohol Deterrents; Alcoholism; Behavior Therapy; Chronic Disease; Disulfiram; Humans; United States | 1999 |
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Ch | 1975 |
[Alcohol and drug interactions].
Topics: Alcoholism; Biotransformation; Chronic Disease; Disulfiram; Drug Interactions; Drug Therapy; Ethanol | 1978 |
[Therapy of alcoholism].
Topics: Acute Disease; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcoholism; Avitaminosis; Chroni | 1976 |
Electron microscopic studies on the cerebral lesions of rats in experimental chronic disulfiram poisoning.
Topics: Animals; Brain; Capillaries; Cerebral Cortex; Chronic Disease; Disease Models, Animal; Disulfiram; H | 1977 |
[Subcutaneous implantation of disulfiram in the treatment of chronic alcoholism].
Topics: Adult; Aged; Alcoholism; Chronic Disease; Disulfiram; Drug Evaluation; Humans; Injections, Subcutane | 1976 |
[Interaction between alcohol and drugs (author's transl)].
Topics: Acetaldehyde; Acute Disease; Alcohol Oxidoreductases; Alcoholism; Aldehyde Oxidoreductases; Analgesi | 1975 |
[Evaluation of disulfiram treatment in chronic alcoholism].
Topics: Alcoholism; Chronic Disease; Disulfiram; Drug Evaluation; Humans; Patient Compliance; Personality; P | 1975 |
Drug therapy in alcoholism.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox | 1970 |
[Clinical aspects of chronic intoxications induced by TMTD].
Topics: Chronic Disease; Disulfiram; Humans; Poisoning | 1973 |
[Effect of withdrawal therapy on urinary excretion of 17-ketosteroids in male patients with chronic alcoholism].
Topics: 17-Ketosteroids; Adult; Alcohol Drinking; Alcoholism; Chronic Disease; Disulfiram; Humans; Insulin; | 1972 |
How to help the chronic alcoholic.
Topics: Alcohol Drinking; Alcoholism; Antidepressive Agents; Chronic Disease; Disulfiram; Humans; Metronidaz | 1972 |
[Disulfiram-like action of Embran. Preliminary report].
Topics: Alcoholism; Chronic Disease; Disulfiram; Drug Antagonism; Ethanol; Humans; Muscles; Tissue Extracts | 1970 |
[Various indices of the blood clotting and anti-clotting systems in chronic alcohlism and theirsynamics during Antbuse therapy].
Topics: Adult; Alcoholism; Blood Coagulation; Calcium; Chronic Disease; Disulfiram; Fibrinogen; Fibrinolysis | 1971 |