disulfiram has been researched along with Chemical and Drug Induced Liver Injury in 83 studies
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disulfiram-induced hepatotoxicity is a recognised entity despite the difficulty in determining its contribution to the damage when alcoholism itself is a frequent cause of liver disease." | 4.77 | Disulfiram hepatotoxicity: a consideration of its mechanism and clinical spectrum. ( Berlin, RG, 1989) |
| "Disulfiram is widely used in the treatment of chronic alcoholism." | 3.71 | Fulminant hepatitis and fatal toxic epidermal necrolysis (Lyell disease) coincident with clarithromycin administration in an alcoholic patient receiving disulfiram therapy. ( Borrás, J; Gutiérrez, F; Jimeno, A; Martín-Hidalgo, A; Masiá, M; Matarredona, J; Navarro, A, 2002) |
| "Disulfiram has been widely used as an adjunct in the treatment of alcoholism and has relatively few side effects." | 3.67 | Disulfiram hepatotoxicity: case report. ( Black, JL; Richardson, JW, 1985) |
| " Two of these had been treated with disulfiram and a drug aetiology could not be excluded, but in six patients no known cause of fulminant hepatitis could be determined and these patients were classified as having hepatitis type non-A non-B." | 3.66 | Hepatitis type A, B, and non-A non-B in fulminant hepatitis. ( Mathiesen, LR; Nielsen, JO; Purcell, RH; Ranek, L; Skinoj, P; Wong, D, 1980) |
| "Disulfiram is used commonly as reinforcement in the treatment of chronic alcoholism." | 3.66 | Fulminant hepatitis associated with disulfiram. Report of a case. ( Dekker, A; Gray, JA; Schade, RR; Shaffer, RD; Van Thiel, DH; Varma, RR, 1983) |
| "Disulfiram has been used as a popular adjunct in programs for alcohol rehabilitation." | 2.42 | Liver transplantation for disulfiram-induced fulminant hepatic failure. ( LaBrecque, DR; Layden, TJ; Mitros, FA; Mohanty, SR, 2004) |
| "Disulfiram is known to cause hepatitis, which is sometimes fatal." | 2.40 | Safety issues concerning the use of disulfiram in treating alcohol dependence. ( Chick, J, 1999) |
| "Disulfiram has been used safely in millions of people since 1948, and we have only few cases reports of severe toxicity." | 2.39 | [Disulfiram (Esperal) toxicity. Apropos of 3 original cases]. ( Boisson, D; Charles, N; Dupuy, O; Flechaire, A; Flocard, F; Rode, G; Vial, C, 1995) |
| "Female CD2F1 mice were dosed with 20 mg/kg BEN iv alone or 24 h after 300 mg/kg disulfiram ip." | 1.39 | Effects of the aldehyde dehydrogenase inhibitor disulfiram on the plasma pharmacokinetics, metabolism, and toxicity of benzaldehyde dimethane sulfonate (NSC281612, DMS612, BEN) in mice. ( Beumer, JH; Clausen, DM; Eiseman, JL; Gasparetto, M; Parise, RA; Rigatti, LH; Smith, CA; Ziegler, JA, 2013) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "Bilirubin was higher (P<0." | 1.33 | Clinical characteristics and prognostic markers in disulfiram-induced liver injury. ( Björnsson, E; Nordlinder, H; Olsson, R, 2006) |
| "When cyanamide-treated alcoholics relapse drinking, the combined effect of cyanamide and alcohol produce more severe portal inflammation along with the emergence of ground-glass inclusions." | 1.31 | Comparison of cyanamide and disulfiram in effects on liver function. ( Ishii, H; Maruyama, K; Okuyama, K; Suzuki, Y; Takahashi, H; Tamai, H; Yokoyama, A, 2000) |
| "The naproxen was the most probable cause of death, but it is impossible to exclude disulfiram as causative agent." | 1.28 | [Fulminating hepatitis after treatment with naproxen and/or disulfiram?]. ( Bell, H; Raknerud, N, 1991) |
| "Acute toxic hepatitis produced by disulphiram is a rare but serious side effect with a lethality about 40%." | 1.28 | [Fatal hepatitis caused by disulfiram]. ( Knudsen, TE; Nielsen-Kudsk, JE, 1990) |
| " Thus, this study shows that agents which sensitize or protect rats from the toxic effects of ANIT, correspondingly stimulate or inhibit the oxidative desulfuration of [35S]ANIT in vivo." | 1.27 | Effect of thiocarbonyl compounds on alpha-naphthylisothiocyanate-induced hepatotoxicity and the urinary excretion of [35S]alpha-naphthylisothiocyanate in the rat. ( Hanzlik, RP; Traiger, GJ; Vyas, KP, 1984) |
| "Disulfiram has been used as an adjunct to the treatment of chronic alcoholism since 1948." | 1.27 | Disulfiram-induced hepatitis--report of a case and review of the literature. ( Nässberger, L, 1984) |
| "Disulfiram pretreatment reduced 24 hour urinary excretion of acetaminophen-mercapturate and- cysteine while excretion of -sulfate and -glucuronide was unchanged." | 1.27 | Disulfiram prevents acetaminophen hepatotoxicity in rats. ( Jørgensen, L; Poulsen, HE; Thomsen, P, 1988) |
| "Disulfiram treatment reduced the acute lethal and hepatotoxic effects of inhaled VDC and reduced the levels of covalent bound radioactivity in the liver and kidney after the intraperitoneal administration of 14C-VDC." | 1.26 | Effect of various treatments on toxicity of inhaled vinylidene chloride. ( Lee, CC; Minor, JL; Seifter, J; Short, RD; Winston, JM, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (53.01) | 18.7374 |
| 1990's | 20 (24.10) | 18.2507 |
| 2000's | 8 (9.64) | 29.6817 |
| 2010's | 10 (12.05) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 3 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 2 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Celada-Sendino, M | 1 |
| Álvarez-Navascués, C | 1 |
| Rodríguez, M | 1 |
| Parise, RA | 1 |
| Beumer, JH | 1 |
| Clausen, DM | 1 |
| Rigatti, LH | 1 |
| Ziegler, JA | 1 |
| Gasparetto, M | 1 |
| Smith, CA | 1 |
| Eiseman, JL | 1 |
| Baekdal, M | 1 |
| Ytting, H | 1 |
| Skalshøi Kjær, M | 1 |
| Schmidt, LE | 1 |
| Wang, LP | 1 |
| Hansen, BA | 1 |
| Larsen, FS | 1 |
| Chick, J | 2 |
| Nakamura, Y | 1 |
| Yokoyama, H | 1 |
| Higuchi, S | 1 |
| Hara, S | 1 |
| Kato, S | 1 |
| Ishii, H | 2 |
| Mohanty, SR | 1 |
| LaBrecque, DR | 1 |
| Mitros, FA | 1 |
| Layden, TJ | 1 |
| Björnsson, E | 1 |
| Nordlinder, H | 1 |
| Olsson, R | 1 |
| Verge, C | 1 |
| Lucena, MI | 1 |
| López-Torres, E | 1 |
| Puche-Garcia, MJ | 1 |
| Fraga, E | 1 |
| Romero-Gomez, M | 1 |
| Andrade, RJ | 1 |
| Vázquez, JJ | 1 |
| Cervera, S | 1 |
| Traiger, GJ | 1 |
| Vyas, KP | 1 |
| Hanzlik, RP | 1 |
| Kristensen, ME | 1 |
| Nässberger, L | 3 |
| Sundkvist, T | 1 |
| Johansson, B | 1 |
| László, B | 1 |
| Kendrey, G | 2 |
| Mathiesen, LR | 1 |
| Skinoj, P | 1 |
| Nielsen, JO | 1 |
| Purcell, RH | 1 |
| Wong, D | 1 |
| Ranek, L | 2 |
| Schade, RR | 1 |
| Gray, JA | 1 |
| Dekker, A | 1 |
| Varma, RR | 1 |
| Shaffer, RD | 1 |
| Van Thiel, DH | 2 |
| Kobborg, N | 1 |
| Søgaard, PE | 1 |
| Kerkhof, SC | 1 |
| de Doelder, PF | 1 |
| Harinck, HI | 1 |
| Stricker, BH | 1 |
| Jørgensen, G | 1 |
| Dupuy, O | 1 |
| Flocard, F | 1 |
| Vial, C | 1 |
| Rode, G | 1 |
| Charles, N | 1 |
| Boisson, D | 1 |
| Flechaire, A | 1 |
| Forns, X | 1 |
| Caballería, J | 1 |
| Bruguera, M | 2 |
| Salmerón, JM | 1 |
| Vilella, A | 1 |
| Mas, A | 1 |
| Parés, A | 2 |
| Rodés, J | 2 |
| Hansen, J | 1 |
| Skausig, OB | 1 |
| Wright, C | 2 |
| Moore, RD | 1 |
| Grodin, DM | 1 |
| Spyker, DA | 1 |
| Gill, EV | 1 |
| Dilts, SL | 2 |
| Schmidt, D | 1 |
| Rabkin, JM | 1 |
| Corless, CL | 1 |
| Orloff, SL | 1 |
| Benner, KG | 1 |
| Flora, KD | 1 |
| Rosen, HR | 1 |
| Olyaei, AJ | 1 |
| Eliasson, E | 1 |
| Stål, P | 1 |
| Oksanen, A | 1 |
| Lytton, S | 1 |
| Tamai, H | 1 |
| Yokoyama, A | 1 |
| Okuyama, K | 1 |
| Takahashi, H | 1 |
| Maruyama, K | 1 |
| Suzuki, Y | 1 |
| Vuorinen, K | 1 |
| Mäkinen, J | 1 |
| Haapamäki, J | 1 |
| Pohjola-Sintonen, S | 1 |
| Masiá, M | 1 |
| Gutiérrez, F | 1 |
| Jimeno, A | 1 |
| Navarro, A | 1 |
| Borrás, J | 1 |
| Matarredona, J | 1 |
| Martín-Hidalgo, A | 1 |
| Haley, TJ | 1 |
| Morris, SJ | 1 |
| Kanner, R | 1 |
| Chiprut, RO | 1 |
| Schiff, ER | 1 |
| Jaeger, RJ | 1 |
| Murphy, SD | 1 |
| Reynolds, ES | 1 |
| Szabo, S | 1 |
| Moslen, MT | 1 |
| Goyer, PF | 1 |
| Major, LF | 1 |
| Skomedal, T | 1 |
| Short, RD | 1 |
| Winston, JM | 1 |
| Minor, JL | 1 |
| Seifter, J | 1 |
| Lee, CC | 1 |
| Buch Andreasen, P | 1 |
| Sziza, M | 1 |
| Fisher, AA | 1 |
| Eisen, HJ | 1 |
| Ginsberg, AL | 1 |
| Lauriault, VV | 1 |
| Khan, S | 1 |
| O'Brien, PJ | 1 |
| Enghusen Poulsen, H | 1 |
| Loft, S | 1 |
| Andersen, JR | 1 |
| Andersen, M | 1 |
| Bell, H | 1 |
| Raknerud, N | 1 |
| Kahn, S | 1 |
| Farnum, JB | 1 |
| Thomas, E | 1 |
| Phillips, M | 1 |
| Knudsen, TE | 1 |
| Nielsen-Kudsk, JE | 1 |
| Laufenburg, HF | 1 |
| Kordahl, H | 1 |
| Mosvold, J | 1 |
| Vanjak, D | 1 |
| Samuel, D | 1 |
| Gosset, F | 1 |
| Derrida, S | 1 |
| Moreau, R | 1 |
| Soupison, T | 1 |
| Soulier, A | 1 |
| Bismuth, H | 1 |
| Sicot, C | 1 |
| Cereda, JM | 1 |
| Bernuau, J | 1 |
| Degott, C | 1 |
| Rueff, B | 1 |
| Benhamou, JP | 1 |
| Berlin, RG | 1 |
| Mason, NA | 1 |
| Yapa, RS | 1 |
| Bartle, WR | 1 |
| Fisher, MM | 1 |
| Kerenyi, N | 1 |
| Vafier, JA | 1 |
| Lake, CR | 1 |
| Iber, FL | 1 |
| Lee, K | 1 |
| Lacoursiere, R | 1 |
| Fuller, R | 1 |
| Mach, T | 1 |
| Jørgensen, L | 2 |
| Thomsen, P | 2 |
| Poulsen, HE | 2 |
| Barth, R | 1 |
| Resnick, RH | 1 |
| Smoller, B | 1 |
| Heredia, D | 1 |
| Kolupaev, GP | 1 |
| Chibisov, VA | 1 |
| Iakovlev, VA | 1 |
| Lukomskiĭ, MI | 1 |
| Petrovich, AA | 1 |
| Igwe, OJ | 1 |
| Hee, SS | 1 |
| Wagner, WD | 1 |
| Nathan, RS | 1 |
| Hill, SY | 1 |
| Smith, L | 1 |
| Black, JL | 1 |
| Richardson, JW | 1 |
| Keeffe, EB | 1 |
| Smith, FW | 1 |
| Breen, KJ | 1 |
| Shaw, J | 1 |
| Levinson, JD | 1 |
| Schenker, S | 1 |
| Scholler, KL | 2 |
| Müller, E | 1 |
| von Plehwe, U | 1 |
12 reviews available for disulfiram and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Liver transplantation for disulfiram-induced fulminant hepatic failure.
Topics: Adolescent; Alcohol Deterrents; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Fema | 2004 |
Alcohol and its effect on endocrine functioning.
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Endocrine Glands; Ethanol; Growth Hormone; Human | 1980 |
[Liver damage attributed to the use of disulfiram].
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Fatal Outcome; Female; Hepatic Encephalop | 1995 |
[Disulfiram (Esperal) toxicity. Apropos of 3 original cases].
Topics: Adult; Brain Diseases; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Nervous S | 1995 |
Safety issues concerning the use of disulfiram in treating alcohol dependence.
Topics: Alcohol Deterrents; Alcoholism; Central Nervous System Diseases; Chemical and Drug Induced Liver Inj | 1999 |
Disulfiram (tetraethylthioperoxydicarbonic diamide): a reappraisal of its toxicity and therapeutic application.
Topics: Adult; Alcoholism; Carcinogens; Chemical and Drug Induced Liver Injury; Disulfiram; Drug Implants; H | 1979 |
Disulfiram-induced hepatitis.
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Male; Middle Aged | 1990 |
Fatal liver failure due to disulfiram.
Topics: Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Hepatic Encephalopat | 1989 |
Disulfiram hepatotoxicity: a consideration of its mechanism and clinical spectrum.
Topics: Alcoholism; Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Humans | 1989 |
Disulfiram-induced hepatitis: case report and review of the literature.
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Liver Function Tests | 1989 |
Disulfiram-induced fulminating hepatitis: guidelines for liver-panel monitoring.
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Liver; Liver | 1988 |
2 trials available for disulfiram and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Systemic hemodynamic effects of treatment with the molecular adsorbents recirculating system in patients with hyperacute liver failure: a prospective controlled trial.
Topics: Acetaminophen; Adult; Alcohol Deterrents; Analgesics, Non-Narcotic; Blood Pressure; Chemical and Dru | 2003 |
Liver toxicity encountered in the Veterans Administration trial of disulfiram in alcoholics.
Topics: Alcoholism; Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Dogs; Hepatitis, Alcoholic; | 1987 |
69 other studies available for disulfiram and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Disulfiram hepatotoxicity: Report of three cases.
Topics: Alcohol Deterrents; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Humans | 2022 |
Effects of the aldehyde dehydrogenase inhibitor disulfiram on the plasma pharmacokinetics, metabolism, and toxicity of benzaldehyde dimethane sulfonate (NSC281612, DMS612, BEN) in mice.
Topics: Aldehyde Dehydrogenase; Animals; Antineoplastic Agents; Area Under Curve; Benzaldehydes; Chemical an | 2013 |
Drug-induced liver injury: a cohort study on patients referred to the Danish transplant center over a five year period.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bilirubin; Chemical and Drug Indu | 2017 |
Disulfiram: cautions on liver function; how to supervise.
Topics: Alcohol Deterrents; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Patient Compliance | 2004 |
Acetaldehyde accumulation suppresses Kupffer cell release of TNF-Alpha and modifies acute hepatic inflammation in rats.
Topics: Acetaldehyde; Animals; Blotting, Northern; Cell Culture Techniques; Chemical and Drug Induced Liver | 2004 |
Clinical characteristics and prognostic markers in disulfiram-induced liver injury.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Alcohol Deterrents; Bilirubin; Biopsy; Causality; Ch | 2006 |
Adverse hepatic reactions associated with calcium carbimide and disulfiram therapy: is there still a role for these drugs?
Topics: Adult; Alcohol Deterrents; Chemical and Drug Induced Liver Injury; Cyanamide; Disulfiram; Drug Inter | 2006 |
Cyanamide-induced liver injury in alcoholics.
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Cyanamide; Cyanides; Disulfiram; Humans; | 1980 |
Effect of thiocarbonyl compounds on alpha-naphthylisothiocyanate-induced hepatotoxicity and the urinary excretion of [35S]alpha-naphthylisothiocyanate in the rat.
Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Ditiocarb; Et | 1984 |
Toxic hepatitis induced by disulfiram in a non-alcoholic.
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Eczema, Dyshidrotic; Female; Humans; Middle Aged | 1981 |
Disulfiram-induced hepatitis--report of a case and review of the literature.
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans | 1984 |
[Disulfiram-induced hepatitis].
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Male; Middle Aged | 1984 |
Hepatotoxicity due to disulfiram.
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Drug Hypersensitivity; Humans | 1984 |
[Acute liver damage during alcohol withdrawal therapy with Anthaethyl].
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Liver; Male | 1984 |
Hepatitis type A, B, and non-A non-B in fulminant hepatitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Chemical and Drug Induced Liver Injury; Disulfiram; Female; | 1980 |
Fulminant hepatitis associated with disulfiram. Report of a case.
Topics: Acute Disease; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Liver; | 1983 |
[Disulfiram hepatitis].
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans | 1981 |
[Effects of drugs on the liver. A review illustrated with 3 clinical cases].
Topics: Acetaminophen; Adult; Aged; Androgens; Chemical and Drug Induced Liver Injury; Denmark; Disulfiram; | 1994 |
Disulfiram-induced hepatitis. Report of four cases and review of the literature.
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Liver Functio | 1994 |
[Antabus in alcohol-induced liver damage].
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Liver Diseases, Alcoholic | 1994 |
Screening for disulfiram-induced liver test dysfunction in an inpatient alcoholism program.
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Enzymes; Female; Hospitalizat | 1993 |
Assessing liver function before initiating disulfiram therapy.
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Contraindications; Disulfiram; Hepatitis, Alcoho | 1996 |
[In the zone between drug insurance and patient insurance. A case of liver damage, requiring transplantation, caused by antabuse].
Topics: Alcohol Deterrents; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Insurance Claim Repo | 1996 |
Patients must be a virtue.
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Halothane; Humans; Liver; Oxidation-Reduction | 1996 |
Liver transplantation for disulfiram-induced hepatic failure.
Topics: Adult; Alcohol Deterrents; Chemical and Drug Induced Liver Injury; Disulfiram; Hepatic Encephalopath | 1998 |
Expression of autoantibodies to specific cytochromes P450 in a case of disulfiram hepatitis.
Topics: Adult; Alcohol Deterrents; Alcoholism; Animals; Autoantibodies; Autoimmunity; Chemical and Drug Indu | 1998 |
Comparison of cyanamide and disulfiram in effects on liver function.
Topics: Adult; Alanine Transaminase; Alcohol Deterrents; Alcoholism; Aspartate Aminotransferases; Chemical a | 2000 |
[A severe liver damage caused by disulfiram treatment].
Topics: Adult; Alcohol Deterrents; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Female; H | 1998 |
Fulminant hepatitis and fatal toxic epidermal necrolysis (Lyell disease) coincident with clarithromycin administration in an alcoholic patient receiving disulfiram therapy.
Topics: Alcohol Deterrents; Alcoholism; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Clari | 2002 |
Disulfiram hepatitis.
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Liver; Male; Middle Aged | 1978 |
Chemical modification of acute hepatotoxicity of vinyl chloride monomer in rats.
Topics: Animals; Aroclors; Chemical and Drug Induced Liver Injury; Disulfiram; Ethanol; Male; Maleates; Phen | 1977 |
Hepatotoxicity in disulfiram-treated patients.
Topics: Adult; Alanine Transaminase; Alcoholism; Alkaline Phosphatase; Chemical and Drug Induced Liver Injur | 1979 |
[Disulfiram induced liver damage].
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Humans | 1979 |
Effect of various treatments on toxicity of inhaled vinylidene chloride.
Topics: Amino Acids, Sulfur; Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Dichloroethylen | 1977 |
Disulfiram hepatotoxicity.
Topics: Adult; Aged; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Liver; | 1977 |
[Morphological studies on the hepatotoxic effect of Thiuram (tetramethylthiuram disulphide) in white rats].
Topics: Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Liver; Liver Cirrhosis; Rats | 1975 |
Letter: Disulfiram hypersensitivity hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Drug Hypersensitivity; Humans; Urticaria | 1975 |
Letter: Disulfiram hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Male; Middle Aged | 1975 |
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome | 1992 |
Disulfiram therapy--adverse drug reactions and interactions.
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Drug Interactions; Female; Hu | 1992 |
[Fulminating hepatitis after treatment with naproxen and/or disulfiram?].
Topics: Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Disulfiram; Drug Evaluation; Female | 1991 |
Disulfiram-induced fulminating hepatitis and monitoring guidelines.
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Liver; Predictive Value of Tests | 1990 |
[Fatal hepatitis caused by disulfiram].
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Male | 1990 |
Case report: negligent treatment with drugs.
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Male; Malpractice; Middle Ag | 1990 |
[Disulfiram and acute liver damage].
Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Liver; Middle Age | 1989 |
[Fulminant hepatitis induced by disulfiram in a patient with alcoholic cirrhosis. Survival after liver transplantation].
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Liver Cirrhosis, Alcoholic; Liver | 1989 |
Dangers of antabuse therapy.
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans; Middle Aged | 1989 |
Disulfiram-induced hepatitis. Report of two cases and review of the literature.
Topics: Adult; Alcoholism; Alkaline Phosphatase; Chemical and Drug Induced Liver Injury; Cyanamide; Disulfir | 1985 |
[Adverse reactions to disulfiram with special reference to hepatotoxicity].
Topics: Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Dyspepsia; Humans | 1988 |
Disulfiram prevents acetaminophen hepatotoxicity in rats.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; | 1988 |
Disulfiram and fulminant hepatitis.
Topics: Acute Disease; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans | 1987 |
Prevention of acetaminophen hepatotoxicity by disulfiram.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Liver; Liver Fun | 1987 |
Cyanamide hepatotoxicity. Incidence and clinico-pathological features.
Topics: Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Cyanamide; Cyanides; Disulfiram; Female; | 1987 |
[Effect of disulfiram on liver function].
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Middle Aged | 1986 |
Interaction between 1,2-dichloroethane and tetraethylthiuram disulfide (disulfiram). II. Hepatotoxic manifestations with possible mechanism of action.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Disulf | 1986 |
Disulfiram and hepatotoxicity.
Topics: Adult; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Humans | 1985 |
Disulfiram hepatotoxicity: case report.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Drug | 1985 |
[Liver injury due to disulfiram].
Topics: Chemical and Drug Induced Liver Injury; Disulfiram; Humans; Liver | 1985 |
Disulfiram hypersensitivity hepatitis.
Topics: Acute Disease; Adult; Alcoholism; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced | 1974 |
The acute effect of alcohol on hepatic coenzyme A and acetyl CoA concentrations.
Topics: Alcoholic Intoxication; Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Coenzyme A; | 1971 |
Modification of the effects of chloroform on the rat liver.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chloroform; Disulfiram; Enzyme Induction; Microsome | 1970 |
[Stimulation and depression of toxicity of chloroform for the liver by drugs].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 1970 |