disulfiram has been researched along with Cataract, Membranous in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "We attempted to develop anti-cataract eye drops using disulfiram (DSF) and low-substituted methylcellulose (MC), and evaluated their anti-cataract effect in terms of the lens opacification vs." | 7.78 | Pharmacokinetic and pharmacodynamic evaluation of the anti-cataract effect of eye drops containing disulfiram and low-substituted methylcellulose using ICR/f rats as a hereditary cataract model. ( Ito, Y; Nagai, N; Takeuchi, N, 2012) |
| "We found a new pharmacological effect of disulfiram (DSF) against rat pups with cataract induced by selenite injection." | 7.70 | Correlation between prevention of cataract development by disulfiram and fates of selenium in selenite-treated rats. ( Cai, H; Ito, Y; Koizumi, Y; Nakao, M; Terao, M, 1999) |
| "We previously demonstrated that topical treatment with disulfiram (DSF) prevented the development of cataracts in sodium selenite-injected rat pups." | 7.70 | Effects of lipid composition on the transcorneal penetration of liposomes containing disulfiram, a potential anti-cataract agent, in the rabbit. ( Cai, H; Hori, R; Ito, Y; Kimura, T; Koizumi, Y; Takagi, S; Terao, M; Tomohiro, M, 2000) |
| " This system increases both the drug solubility in aqueous eye drops and the permeability of drug into the rabbit eye, by the formation of a drug-cyclodextrin inclusion complex, and so enhances the ocular bioavailability and anti-cataract effect of DSF." | 5.32 | Bioavailability and anticataract effects of a topical ocular drug delivery system containing disulfiram and hydroxypropyl-beta-cyclodextrin on selenite-treated rats. ( Ito, Y; Li, D; Nabekura, T; Wang, S; Wu, C; Zhang, J, 2004) |
| "We attempted to develop anti-cataract eye drops using disulfiram (DSF) and low-substituted methylcellulose (MC), and evaluated their anti-cataract effect in terms of the lens opacification vs." | 3.78 | Pharmacokinetic and pharmacodynamic evaluation of the anti-cataract effect of eye drops containing disulfiram and low-substituted methylcellulose using ICR/f rats as a hereditary cataract model. ( Ito, Y; Nagai, N; Takeuchi, N, 2012) |
| "We found a new pharmacological effect of disulfiram (DSF) against rat pups with cataract induced by selenite injection." | 3.70 | Correlation between prevention of cataract development by disulfiram and fates of selenium in selenite-treated rats. ( Cai, H; Ito, Y; Koizumi, Y; Nakao, M; Terao, M, 1999) |
| "We previously demonstrated that topical treatment with disulfiram (DSF) prevented the development of cataracts in sodium selenite-injected rat pups." | 3.70 | Effects of lipid composition on the transcorneal penetration of liposomes containing disulfiram, a potential anti-cataract agent, in the rabbit. ( Cai, H; Hori, R; Ito, Y; Kimura, T; Koizumi, Y; Takagi, S; Terao, M; Tomohiro, M, 2000) |
| "Disulfiram, a dimer of diethyldithiocarbamate (DDC) which is a strong radical scavenger, is known to prevent cataract development." | 3.70 | Preparation and in vivo ocular absorption studies of disulfiram solid dispersion. ( Cai, H; Hori, R; Ito, Y; Nabekura, T; Terao, M, 2000) |
| " This system increases both the drug solubility in aqueous eye drops and the permeability of drug into the rabbit eye, by the formation of a drug-cyclodextrin inclusion complex, and so enhances the ocular bioavailability and anti-cataract effect of DSF." | 1.32 | Bioavailability and anticataract effects of a topical ocular drug delivery system containing disulfiram and hydroxypropyl-beta-cyclodextrin on selenite-treated rats. ( Ito, Y; Li, D; Nabekura, T; Wang, S; Wu, C; Zhang, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fursova, AZ | 1 |
| Rumyantseva, YV | 1 |
| Kolosova, NG | 1 |
| Kedik, SA | 1 |
| Panov, AV | 1 |
| Tyukova, VC | 1 |
| Liu, C | 1 |
| Lan, Q | 1 |
| He, W | 1 |
| Nie, C | 1 |
| Zhang, C | 1 |
| Xu, T | 1 |
| Jiang, T | 1 |
| Wang, S | 3 |
| Nagai, N | 6 |
| Ito, Y | 12 |
| Sternberg, K | 1 |
| Terwee, T | 1 |
| Stachs, O | 1 |
| Guthoff, R | 1 |
| Löbler, M | 1 |
| Schmitz, KP | 1 |
| Takeuchi, N | 3 |
| Nabekura, T | 4 |
| Koizumi, Y | 3 |
| Nakao, M | 2 |
| Tomohiro, M | 3 |
| Inomata, M | 1 |
| Kitagawa, S | 1 |
| Li, D | 1 |
| Zhang, J | 1 |
| Wu, C | 1 |
| Takeda, M | 1 |
| Kamei, A | 1 |
| Jiang, TY | 1 |
| Wang, SL | 1 |
| Liu, Y | 1 |
| Nie, SF | 1 |
| Wu, CF | 1 |
| Cai, H | 3 |
| Terao, M | 3 |
| Hori, R | 2 |
| Kimura, T | 1 |
| Takagi, S | 1 |
15 other studies available for disulfiram and Cataract, Membranous
| Article | Year |
|---|---|
[Disulfiram inhibites the development of cataract in OXYS rats].
Topics: Animals; Cataract; Disulfiram; Humans; Lens, Crystalline; Rats | 2016 |
Octa-arginine modified lipid emulsions as a potential ocular delivery system for disulfiram: A study of the corneal permeation, transcorneal mechanism and anti-cataract effect.
Topics: Animals; Cataract; Cornea; Coumarins; Disulfiram; Drug Delivery Systems; Emulsions; Fluorescent Dyes | 2017 |
Excessive hydrogen peroxide enhances the attachment of amyloid β1-42 in the lens epithelium of UPL rats, a hereditary model for cataracts.
Topics: Age Factors; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secret | 2014 |
Drug-induced secondary cataract prevention: experimental ex vivo and in vivo results with disulfiram, methotrexate and actinomycin D.
Topics: Animals; Capsulorhexis; Cataract; Cell Count; Cell Culture Techniques; Cell Proliferation; Dactinomy | 2010 |
Pharmacokinetic and pharmacodynamic evaluation of the anti-cataract effect of eye drops containing disulfiram and low-substituted methylcellulose using ICR/f rats as a hereditary cataract model.
Topics: Animals; Antioxidants; Cataract; Disease Models, Animal; Disulfiram; Drug Carriers; Hypromellose Der | 2012 |
Delay of cataract development in hereditary cataract UPL rats by disulfiram and aminoguanidine.
Topics: Aging; Animals; Antioxidants; Calcium; Cataract; Crystallins; Disulfiram; Enzyme Inhibitors; Eye Dis | 2003 |
Changes in plasma membrane Ca2+ -ATPase expression and ATP content in lenses of hereditary cataract UPL rats.
Topics: Adenosine Triphosphate; Animals; Calcium-Transporting ATPases; Cataract; Cell Membrane; Disease Mode | 2004 |
Bioavailability and anticataract effects of a topical ocular drug delivery system containing disulfiram and hydroxypropyl-beta-cyclodextrin on selenite-treated rats.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Topical; Animals; Aqueous Humor; beta-Cyclodextri | 2004 |
Delay in ICR/f rat lens opacification by the instillation of eye drops containing disulfiram and hydroxypropyl-beta-cyclodextrin inclusion complex.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; beta-Cyclodextrins; Cataract; Cornea; Disulfiram; Ditioc | 2007 |
Adverse effects of excessive nitric oxide on cytochrome c oxidase in lenses of hereditary cataract UPL rats.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Cataract; Disease Models, Animal; Disulfiram; | 2007 |
In vitro cell culture model for anti-cataract drug penetration studies.
Topics: Aldehyde Dehydrogenase; Animals; Cataract; Cell Line; Cell Membrane Permeability; Collagen Type IV; | 2007 |
Effect of disulfiram eye drops on lipid peroxide formation via excessive nitric oxide in lenses of hereditary cataract ICR/f rats.
Topics: Alcohol Deterrents; Animals; Calcium; Calcium-Transporting ATPases; Cataract; Cyclodextrins; Disulfi | 2008 |
Correlation between prevention of cataract development by disulfiram and fates of selenium in selenite-treated rats.
Topics: Administration, Intranasal; Animals; Cataract; Disulfiram; Ditiocarb; Drug Carriers; Female; Liposom | 1999 |
Effects of lipid composition on the transcorneal penetration of liposomes containing disulfiram, a potential anti-cataract agent, in the rabbit.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Antioxidants; Calorimetry, Differential Scanning; Catar | 2000 |
Preparation and in vivo ocular absorption studies of disulfiram solid dispersion.
Topics: Absorption; Animals; Cataract; Dimerization; Disulfiram; Ditiocarb; Drug Carriers; Drug Compounding; | 2000 |