disulfiram has been researched along with Cancer of Pancreas in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatic cancer cell lines with mutated ras underwent an alternative form of cell death (aponecrosis) when treated concomitantly with clinically achievable concentrations of arsenic trioxide, ascorbic acid, and disulfiram (Antabuse; AAA)." | 3.79 | Redirecting apoptosis to aponecrosis induces selective cytotoxicity to pancreatic cancer cells through increased ROS, decline in ATP levels, and VDAC. ( Brandt-Rauf, P; Cassai, N; Dinnen, RD; Fine, RL; Mao, Y; Nichols, G; Qiu, W; Slavkovich, VN; Su, GH, 2013) |
| "Disulfiram (DSF), which is an inhibitor of aldehyde dehydrogenase (ALDH) and approved by the FDA for the treatment of alcoholism previously, has been repurposed for use as a cancer treatment because of its potent effect in preclinical studies." | 1.72 | Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells. ( Chang, X; Feng, Z; Gao, J; Li, X; Liu, F; Wang, Y; Xiao, L; Yao, Z; Zhang, X, 2022) |
| "Desmoplasia in human pancreatic cancer (PC) promotes cancer progression and hinders effective drug delivery." | 1.43 | Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia. ( Ali, SA; Batra, SK; Chakraborty, S; Das, B; Dash, P; Jain, S; Mohanty, AK; Panda, SK; Senapati, S; Suklabaidya, S; Swaminathan, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Z | 1 |
| Xie, X | 1 |
| Tan, G | 1 |
| Xie, F | 1 |
| Liu, N | 1 |
| Li, W | 1 |
| Sun, X | 1 |
| Yao, Z | 1 |
| Li, X | 1 |
| Gao, J | 1 |
| Wang, Y | 2 |
| Xiao, L | 1 |
| Chang, X | 1 |
| Liu, F | 1 |
| Feng, Z | 1 |
| Zhang, X | 2 |
| Cong, J | 1 |
| Zhang, N | 1 |
| Liu, L | 2 |
| Soukup, K | 1 |
| Michelakos, T | 1 |
| Hong, T | 1 |
| DeLeo, A | 1 |
| Cai, L | 1 |
| Sabbatino, F | 1 |
| Ferrone, S | 1 |
| Lee, H | 1 |
| Levina, V | 1 |
| Fuchs, B | 1 |
| Tanabe, K | 1 |
| Lillemoe, K | 1 |
| Ferrone, C | 1 |
| Wang, X | 1 |
| Han, J | 1 |
| Yue, X | 1 |
| Chang, J | 1 |
| Shi, W | 1 |
| Hua, Y | 1 |
| Dinnen, RD | 1 |
| Mao, Y | 1 |
| Qiu, W | 1 |
| Cassai, N | 1 |
| Slavkovich, VN | 1 |
| Nichols, G | 1 |
| Su, GH | 1 |
| Brandt-Rauf, P | 1 |
| Fine, RL | 1 |
| Kim, SK | 1 |
| Kim, H | 2 |
| Lee, DH | 1 |
| Kim, TS | 1 |
| Kim, T | 1 |
| Chung, C | 1 |
| Koh, GY | 1 |
| Lim, DS | 1 |
| Suklabaidya, S | 1 |
| Das, B | 1 |
| Ali, SA | 1 |
| Jain, S | 1 |
| Swaminathan, S | 1 |
| Mohanty, AK | 1 |
| Panda, SK | 1 |
| Dash, P | 1 |
| Chakraborty, S | 1 |
| Batra, SK | 1 |
| Senapati, S | 1 |
7 other studies available for disulfiram and Cancer of Pancreas
| Article | Year |
|---|---|
Disulfiram Synergizes with SRC Inhibitors to Suppress the Growth of Pancreatic Ductal Adenocarcinoma Cells in Vitro and in Vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cell Line, Tu | 2021 |
Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Disulfiram; Humans; Pancreatic Neoplasms; Phosphatidylinosit | 2022 |
Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Disulfiram; Humans; Pancreatic Neoplasms; Phosphatidylinosit | 2022 |
Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Disulfiram; Humans; Pancreatic Neoplasms; Phosphatidylinosit | 2022 |
Transcription factor p8 regulates autophagy in response to disulfiram via PI3K/mTOR/p70S6K signaling pathway in pancreatic cancer cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Disulfiram; Humans; Pancreatic Neoplasms; Phosphatidylinosit | 2022 |
A novel chemoradiation targeting stem and nonstem pancreatic cancer cells by repurposing disulfiram.
Topics: Acetaldehyde Dehydrogenase Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Carc | 2017 |
A binuclear complex constituted by diethyldithiocarbamate and copper(I) functions as a proteasome activity inhibitor in pancreatic cancer cultures and xenografts.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cop | 2013 |
Redirecting apoptosis to aponecrosis induces selective cytotoxicity to pancreatic cancer cells through increased ROS, decline in ATP levels, and VDAC.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Asc | 2013 |
Reversing the intractable nature of pancreatic cancer by selectively targeting ALDH-high, therapy-resistant cancer cells.
Topics: Aldehyde Dehydrogenase; Analysis of Variance; Animals; Blotting, Western; Carcinoma, Pancreatic Duct | 2013 |
Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia.
Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disulfira | 2016 |