disulfiram has been researched along with Cancer of Ovary in 7 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among gynecological cancers, ovarian cancer has a high mortality rate." | 1.91 | Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Antitumor Activity of Disulfiram and Cisplatin in Ovarian Cancer. ( Deng, Q; Ding, C; Du, R; Hong, B; Li, K; Nie, J; Qi, J; Sun, F; Sun, Q; Wang, H; Wang, W; Zhong, W, 2023) |
| " A synergistic treatment with drug supporting activity could maximize the cytotoxic effects of chemotherapeutic agents on tumor cells while decreasing the dosage of each drug to potentially reduce toxicity." | 1.72 | Blockade of ALDH in Cisplatin-Resistant Ovarian Cancer Stem Cells In Vitro Synergistically Enhances Chemotherapy-Induced Cell Death. ( Guo, F; Kaufmann, AM; Sehouli, J; Yang, Z, 2022) |
| "Disulfiram (DSF) is a drug used for treatment of alcoholism that has also displayed promising anti-cancer activity." | 1.51 | Inhibitory effect on ovarian cancer ALDH+ stem-like cells by Disulfiram and Copper treatment through ALDH and ROS modulation. ( Albers, AE; Guo, F; Kaufmann, AM; Kulbe, H; Sehouli, J; Yang, Z, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, F | 2 |
| Yang, Z | 2 |
| Sehouli, J | 2 |
| Kaufmann, AM | 2 |
| Du, R | 1 |
| Sun, F | 1 |
| Li, K | 1 |
| Qi, J | 1 |
| Zhong, W | 1 |
| Wang, W | 1 |
| Sun, Q | 1 |
| Deng, Q | 1 |
| Wang, H | 1 |
| Nie, J | 1 |
| Ding, C | 1 |
| Hong, B | 1 |
| Gan, Y | 1 |
| Liu, T | 1 |
| Feng, W | 1 |
| Wang, L | 1 |
| Li, LI | 1 |
| Ning, Y | 1 |
| Kulbe, H | 1 |
| Albers, AE | 1 |
| Torralba, M | 1 |
| Farra, R | 1 |
| Maddaloni, M | 1 |
| Grassi, M | 1 |
| Dapas, B | 1 |
| Grassi, G | 1 |
| Jiao, Y | 1 |
| Hannafon, BN | 1 |
| Zhang, RR | 1 |
| Fung, KM | 1 |
| Ding, WQ | 1 |
| O'Brien, A | 1 |
| Barber, JE | 1 |
| Reid, S | 1 |
| Niknejad, N | 1 |
| Dimitroulakos, J | 1 |
7 other studies available for disulfiram and Cancer of Ovary
| Article | Year |
|---|---|
Blockade of ALDH in Cisplatin-Resistant Ovarian Cancer Stem Cells In Vitro Synergistically Enhances Chemotherapy-Induced Cell Death.
Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Disulfiram; Female; Humans; Necrosis; Neoplastic Stem C | 2022 |
Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Antitumor Activity of Disulfiram and Cisplatin in Ovarian Cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cisplatin; Disulfir | 2023 |
Drug repositioning of disulfiram induces endometrioid epithelial ovarian cancer cell death via the both apoptosis and cuproptosis pathways.
Topics: Animals; Apoptosis; Carcinoma, Ovarian Epithelial; Cell Death; Copper; Disulfiram; Drug Repositionin | 2023 |
Inhibitory effect on ovarian cancer ALDH+ stem-like cells by Disulfiram and Copper treatment through ALDH and ROS modulation.
Topics: Aldehyde Dehydrogenase; Apoptosis; Cell Cycle; Cell Line, Tumor; Cisplatin; Copper; Disulfiram; Fema | 2019 |
Drugs Repurposing in High-Grade Serous Ovarian Cancer.
Topics: Antineoplastic Agents; Disulfiram; Drug Repositioning; Female; Humans; Ovarian Neoplasms; Pharmaceut | 2020 |
Docosahexaenoic acid and disulfiram act in concert to kill cancer cells: a mutual enhancement of their anticancer actions.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Disulfiram; D | 2017 |
Enhancement of cisplatin cytotoxicity by disulfiram involves activating transcription factor 3.
Topics: Activating Transcription Factor 3; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; C | 2012 |