disulfiram has been researched along with Body Weight in 30 studies
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was to explore the influence of treatment with disulfiram, a small molecule inhibitor to gasdermin D, on the formation and progression of experimental abdominal aortic aneurysms (AAA)." | 8.31 | Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms. ( Ge, Y; Guo, J; Ikezoe, T; Li, Z; Qin, M; Shi, J; Shoji, T; Wang, Y; Xu, B, 2023) |
| "Obesity is a top public health concern, and a molecule that safely treats obesity is urgently needed." | 5.56 | Disulfiram Treatment Normalizes Body Weight in Obese Mice. ( Ali, A; Aon, MA; Becker, KG; Bernier, M; Cai, H; Cogger, VC; Cuervo, AM; de Cabo, R; Di Francesco, A; Di Germanio, C; Diaz, A; Egan, JM; Enamorado, IN; Fernandez-Hernando, C; Fishbein, K; Gao, B; Guiterrez, V; Harney, D; Kaiser, T; Kim, EY; Koay, YC; Lakatta, EG; Larance, M; LeCouteur, DG; Mach, J; Mitchell, SJ; O'Sullivan, J; Petr, MA; Price, NL; Pulpitel, T; Seo, W; Singh, A; Spencer, RG; Wahl, D; Wang, M; Wang, Y; Warren, A; Zhang, J; Zhang, L, 2020) |
| " This study was to explore the influence of treatment with disulfiram, a small molecule inhibitor to gasdermin D, on the formation and progression of experimental abdominal aortic aneurysms (AAA)." | 4.31 | Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms. ( Ge, Y; Guo, J; Ikezoe, T; Li, Z; Qin, M; Shi, J; Shoji, T; Wang, Y; Xu, B, 2023) |
| " The objective of this study was to determine if disulfiram would inhibit the induction of bladder cancer in rats given BCPN, as reported for BHBN (Cancer Res." | 3.66 | The effect of disulfiram on the carcinogenicity of N-butyl-N-(3-carboxypropyl)nitrosamine in the rat. ( Daniel, DS; Irving, CC; Murphy, WM, 1983) |
| "Obesity is a top public health concern, and a molecule that safely treats obesity is urgently needed." | 1.56 | Disulfiram Treatment Normalizes Body Weight in Obese Mice. ( Ali, A; Aon, MA; Becker, KG; Bernier, M; Cai, H; Cogger, VC; Cuervo, AM; de Cabo, R; Di Francesco, A; Di Germanio, C; Diaz, A; Egan, JM; Enamorado, IN; Fernandez-Hernando, C; Fishbein, K; Gao, B; Guiterrez, V; Harney, D; Kaiser, T; Kim, EY; Koay, YC; Lakatta, EG; Larance, M; LeCouteur, DG; Mach, J; Mitchell, SJ; O'Sullivan, J; Petr, MA; Price, NL; Pulpitel, T; Seo, W; Singh, A; Spencer, RG; Wahl, D; Wang, M; Wang, Y; Warren, A; Zhang, J; Zhang, L, 2020) |
| "In disulfiram-treated rats, only 35 to 36% of the administered 14C was eliminated in the urine with 41 to 55% as unchanged EDC in the breath." | 1.28 | Ethylene dichloride: the influence of disulfiram or ethanol on oncogenicity, metabolism, and DNA covalent binding in rats. ( Cheever, KL; Cholakis, JM; el-Hawari, AM; Kovatch, RM; Weisburger, EK, 1990) |
| "Benzyl isothiocyanate was most effective in these "portal of entry" organs but less effective than bisethylxanthogen in the other extrahepatic organs examined." | 1.27 | Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs. ( Barretto, PB; Benson, AM, 1985) |
| "In phenobarbital-treated rats disulfiram 100 mg/kg did not alter the induction response as indicated by the cytochrome P-450 content, but inhibited the p-nitroanisole activity to control levels." | 1.26 | Effect of long-term disulfiram administration on rat liver. ( Andreasen, PB; Milandri, M; Poulsen, HE; Ranek, L, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (70.00) | 18.7374 |
| 1990's | 5 (16.67) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, J | 1 |
| Shi, J | 1 |
| Qin, M | 1 |
| Wang, Y | 2 |
| Li, Z | 1 |
| Shoji, T | 1 |
| Ikezoe, T | 1 |
| Ge, Y | 1 |
| Xu, B | 1 |
| Bernier, M | 1 |
| Mitchell, SJ | 1 |
| Wahl, D | 1 |
| Diaz, A | 1 |
| Singh, A | 1 |
| Seo, W | 1 |
| Wang, M | 1 |
| Ali, A | 1 |
| Kaiser, T | 1 |
| Price, NL | 1 |
| Aon, MA | 1 |
| Kim, EY | 1 |
| Petr, MA | 1 |
| Cai, H | 1 |
| Warren, A | 1 |
| Di Germanio, C | 1 |
| Di Francesco, A | 1 |
| Fishbein, K | 1 |
| Guiterrez, V | 1 |
| Harney, D | 1 |
| Koay, YC | 1 |
| Mach, J | 1 |
| Enamorado, IN | 1 |
| Pulpitel, T | 1 |
| Zhang, J | 1 |
| Zhang, L | 1 |
| Spencer, RG | 1 |
| Becker, KG | 1 |
| Egan, JM | 1 |
| Lakatta, EG | 1 |
| O'Sullivan, J | 1 |
| Larance, M | 1 |
| LeCouteur, DG | 1 |
| Cogger, VC | 1 |
| Gao, B | 1 |
| Fernandez-Hernando, C | 1 |
| Cuervo, AM | 1 |
| de Cabo, R | 1 |
| He, H | 1 |
| Markoutsa, E | 1 |
| Li, J | 1 |
| Xu, P | 1 |
| Nagai, N | 1 |
| Murao, T | 1 |
| Okamoto, N | 1 |
| Ito, Y | 1 |
| HEATH, RG | 1 |
| NESSELHOF, W | 1 |
| BISHOP, MP | 1 |
| BYERS, LW | 1 |
| Savolainen, K | 1 |
| Hervonen, H | 1 |
| Lehto, VP | 1 |
| Mattila, MJ | 1 |
| Derévenco, P | 1 |
| Stoica, N | 1 |
| Vaida, A | 1 |
| Perier, C | 1 |
| Janin, J | 1 |
| Pierre-Louis, S | 1 |
| Frey, J | 1 |
| Irving, CC | 1 |
| Daniel, DS | 1 |
| Murphy, WM | 1 |
| Malejka-Giganti, D | 1 |
| McIver, RC | 1 |
| Rydell, RE | 1 |
| Wong, LC | 1 |
| Winston, JM | 1 |
| Hong, CB | 1 |
| Plotnick, H | 1 |
| Bertram, B | 1 |
| Schuhmacher, J | 1 |
| Frei, E | 1 |
| Frank, N | 1 |
| Wiessler, M | 1 |
| Milandri, M | 1 |
| Poulsen, HE | 1 |
| Ranek, L | 1 |
| Andreasen, PB | 1 |
| Rahman, MA | 1 |
| Grunberg, NE | 1 |
| Mueller, GP | 1 |
| Rogers, WK | 1 |
| Benowitz, NL | 1 |
| Wilson, KM | 1 |
| Abbott, JA | 1 |
| Roe, DA | 1 |
| Hoover, DM | 1 |
| Hoyt, JA | 1 |
| Seyler, DE | 1 |
| Abbott, DL | 1 |
| Hoffman, WP | 1 |
| Buening, MK | 1 |
| Luthman, J | 1 |
| Olson, L | 2 |
| Björklund, H | 2 |
| Henschen, A | 1 |
| Hoffer, B | 2 |
| Oskarsson, A | 3 |
| McLellan, E | 1 |
| Bird, RP | 1 |
| Cheever, KL | 1 |
| Cholakis, JM | 1 |
| el-Hawari, AM | 1 |
| Kovatch, RM | 1 |
| Weisburger, EK | 1 |
| Edwards, HM | 1 |
| Benson, AM | 1 |
| Barretto, PB | 1 |
| Igwe, OJ | 2 |
| Que Hee, SS | 1 |
| Wagner, WD | 2 |
| Palmer, MR | 1 |
| Lind, B | 1 |
| Hee, SS | 1 |
| Royer, RJ | 1 |
| Marquis, P | 1 |
| Morrot, MJ | 1 |
| Alexandre, P | 1 |
| Holck, HG | 1 |
| Lish, PM | 1 |
| Sjogren, DW | 1 |
| Westerfeld, WW | 1 |
| Malone, MH | 1 |
| Gjessing, LR | 1 |
| Millard, SA | 1 |
| Roggeveen, AE | 1 |
| Geyer, SJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Body Weight Response With Disulfiram in Humans. Concept Testing Study[NCT05162001] | Early Phase 1 | 10 participants (Anticipated) | Interventional | 2021-11-21 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for disulfiram and Body Weight
| Article | Year |
|---|---|
Interactions between drugs and nutrients.
Topics: Adult; Animals; Appetite; Body Weight; Cheese; Child; Disulfiram; Eating; Ethanol; Food; Humans; Hyp | 1979 |
29 other studies available for disulfiram and Body Weight
| Article | Year |
|---|---|
Pharmacological Inhibition of Gasdermin D Suppresses Angiotensin II-Induced Experimental Abdominal Aortic Aneurysms.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Body Weight; Disease Models, Animal; Disulfiram | 2023 |
Disulfiram Treatment Normalizes Body Weight in Obese Mice.
Topics: Animals; Anti-Obesity Agents; Body Weight; Diet; Disulfiram; Female; Male; Mice; Mice, Inbred C57BL; | 2020 |
Repurposing disulfiram for cancer therapy via targeted nanotechnology through enhanced tumor mass penetration and disassembly.
Topics: Acrylates; Animals; Body Weight; Cell Line, Tumor; Cell Proliferation; Disulfiram; Drug Repositionin | 2018 |
Disulfiram reduces elevated blood glucose levels in Otsuka Long-Evans Tokushima Fatty (OLETF) rats, a model of type 2 diabetes.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Disulfiram; | 2009 |
BEHAVIORAL AND METABOLIC CHANGES ASSOCIATED WITH ADMINISTRATION OF TETRAETHYLTHIURAM DISULFIDE (ANTABUSE).
Topics: Autonomic Nervous System; Blood Chemical Analysis; Body Weight; Disulfiram; Electroencephalography; | 1965 |
Neurotoxic effects of disulfiram on autonomic nervous system in rat.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Autonomic Nervous System; Body Weight; Disulfiram; His | 1984 |
Other effects of monoaminergic inhibition with 6-hydroxydopamine and of disulfiram on the response to exercise in rats.
Topics: Animals; Animals, Newborn; Biogenic Amines; Body Weight; Disulfiram; Female; Hydroxydopamines; Male; | 1981 |
Reversal of changes in lipoprotein A and lipoprotein B cholesterol during and for a year after a detoxication treatment program in chronic alcoholism.
Topics: Adult; Aged; Alcoholism; Apolipoproteins; Body Weight; Cholesterol; Disulfiram; Female; Follow-Up St | 1983 |
The effect of disulfiram on the carcinogenicity of N-butyl-N-(3-carboxypropyl)nitrosamine in the rat.
Topics: Animals; Body Weight; Carcinogens; Disulfiram; Male; Neoplasms, Experimental; Nitrosamines; Rats; Ra | 1983 |
Inhibitory effect of disulfiram on rat mammary tumor induction by N-2-fluorenylacetamide and on its metabolic conversion to N-hydroxy-N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; Adenocarcinoma; Adenofibroma; Adenoma; Animals; Biotransformation; Body Weigh | 1980 |
Carcinogenicity and toxicity of 1,2-dibromoethane in the rat.
Topics: Animals; Blood; Body Weight; Disulfiram; Eating; Ethylene Dibromide; Female; Hydrocarbons, Brominate | 1982 |
Effects of disulfiram on mixed function oxidase system and trace element concentration in the liver of rats.
Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Disulfiram; Kinetics; Liver; Male; Microsomes, | 1982 |
Effect of long-term disulfiram administration on rat liver.
Topics: Animals; Body Weight; Cytochrome P-450 Enzyme System; Disulfiram; Female; Glutathione; Liver; Micros | 1980 |
Disulfiram causes sustained behavioral and biochemical effects in rats.
Topics: Alcohol Deterrents; alpha-MSH; Analysis of Variance; Animals; Body Weight; Disulfiram; Drug Evaluati | 1997 |
Effect of disulfiram on adrenergic function.
Topics: Adult; Blood Pressure; Body Weight; Catecholamines; Disulfiram; Heart Rate; Humans; Male; Nitroglyce | 1979 |
Comparative effects of disulfiram and N-methyltetrazolethiol on spermatogenic development in young CD rats.
Topics: Aldehyde Dehydrogenase; Animals; Animals, Newborn; Body Weight; Disulfiram; Flow Cytometry; Male; Or | 1991 |
Combined lead acetate and disulfiram treatment-induced alterations of glial fibrillary acidic protein (GFA) immunoreactive astrocytes in brain smears.
Topics: Animals; Animals, Suckling; Astrocytes; Body Weight; Cerebellar Cortex; Disulfiram; Drug Interaction | 1991 |
Effect of disulfiram on 1,2-dimethylhydrazine- and azoxymethane-induced aberrant crypt foci.
Topics: 1,2-Dimethylhydrazine; Animals; Azoxymethane; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Di | 1991 |
Ethylene dichloride: the influence of disulfiram or ethanol on oncogenicity, metabolism, and DNA covalent binding in rats.
Topics: Animals; Body Weight; Carcinogens; Disulfiram; DNA; Drinking; Drug Synergism; Eating; Ethanol; Ethyl | 1990 |
The effect of dietary cholecalciferol, 25-hydroxycholecalciferol and 1,25-dihydroxycholecalciferol on the development of tibial dyschondroplasia in broiler chickens in the absence and presence of disulfiram.
Topics: Animals; Body Weight; Bone and Bones; Calcifediol; Calcitriol; Calcium; Chickens; Cholecalciferol; D | 1989 |
Effects of perinatal treatment with lead and disulfiram on ALAD activity in blood, liver and kidney and urinary ALA excretion in rats.
Topics: Aminolevulinic Acid; Animals; Body Weight; Disulfiram; Drinking; Female; Hematocrit; Kidney; Lead; L | 1989 |
Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs.
Topics: Animals; Body Weight; Crystallization; Disulfides; Disulfiram; Ditiocarb; Female; Glutathione Transf | 1985 |
Interaction between 1,2-dichloroethane and disulfiram. I. Toxicologic effects.
Topics: Aerosols; Animals; Body Weight; Disulfiram; Drug Interactions; Ethylene Dichlorides; Hydrocarbons, C | 1986 |
Increased lead concentration in brain and potentiation of lead-induced neuronal depression in rats after combined treatment with lead and disulfiram.
Topics: Animals; Body Weight; Brain; Disulfiram; Drug Synergism; Female; Heart Conduction System; Lead; Neur | 1986 |
Interaction between 1,2-dichloroethane and tetraethylthiuram disulfide (disulfiram). II. Hepatotoxic manifestations with possible mechanism of action.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Disulf | 1986 |
[Thrombopenic efect of disulfiram in the rabbit].
Topics: Administration, Oral; Animals; Autoanalysis; Blood Cell Count; Blood Platelets; Body Weight; Disulfi | 1974 |
Effects of disulfiram on growth, longevity, and reproduction of the albino rat.
Topics: Age Factors; Animals; Ascorbic Acid; Blood Cell Count; Body Weight; Diet; Disulfiram; Female; Growth | 1970 |
Effect of thyroxine, pyridoxine, orphenadrine-HCl, resperine and disulfiram in periodic catatonia.
Topics: Basal Metabolism; Body Temperature; Body Weight; Catatonia; Catecholamines; Disulfiram; Humans; Inje | 1967 |
Biochemical effects due to interaction of lithium ions and disulfiram in rats.
Topics: Animals; Body Weight; Brain; Disulfiram; Lithium; Male; Mixed Function Oxygenases; Mortality; Muscle | 1969 |