Page last updated: 2024-10-26

disulfiram and Bipolar Disorder

disulfiram has been researched along with Bipolar Disorder in 18 studies

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Although disulfiram and naltrexone have been approved by the Food and Drug Administration for the treatment of alcoholism, no medications have been approved for individuals with alcohol dependence and comorbid psychiatric disorders."5.12Naltrexone and disulfiram in patients with alcohol dependence and current depression. ( Carroll, K; Levinson, C; Nich, C; Petrakis, I; Poling, J; Ralevski, E; Rounsaville, B, 2007)
"Disulfiram-potentiation was significant in constantly depressed patients, and in questionable controls due to possible subclinical depression or somatic factors which may cause 'false-positive' results."2.67Can disulfiram potentiate the dexamethasone suppression test in depressive patients? ( Bergsholm, P; Holsten, F; Myking, O; Oulie, D, 1993)
"Rates of alcohol and other substance abuse or dependence disorders are substantially higher in persons with bipolar disorders than in the general population, reaching approximately 61% in patients with bipolar I disorder."2.43Management of comorbid bipolar disorder and substance abuse. ( Brown, ES, 2006)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's3 (16.67)18.2507
2000's5 (27.78)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amireche, N1
Petit, JS1
Bankole, E1
Fournet-Fayard, A1
Appriou, M1
Leon, A1
OSTENFELD, I1
Petrakis, IL1
Nich, C2
Ralevski, E2
Brown, ES1
Petrakis, I1
Levinson, C1
Carroll, K1
Poling, J1
Rounsaville, B1
Ceylan, ME1
Turkcan, A1
Mutlu, E1
Onal, O1
Li, MY1
Shen, YC1
Lacoursiere, RB1
Swatek, R1
Auriol, B1
Bardou, E1
Lambic, C1
Bergsholm, P1
Oulie, D1
Holsten, F1
Myking, O1
Iruela, LM1
IbaƱez-Rojo, V1
Caballero, L1
Baca, E1
Simon, LT1
Hsu, B1
Adornato, BT1
Nunes, E1
Quitkin, F1
Bakish, D1
Lapierre, YD1
Goldstein, M1
Danielczyk, W1
Manz, F1
Takahashi, R1
Nagao, Y1
Tsuchiya, K1
Takamizawa, M1
Kobayashi, T1
Toru, M1
Kobayashi, K1
Kariya, T1

Reviews

2 reviews available for disulfiram and Bipolar Disorder

ArticleYear
Management of comorbid bipolar disorder and substance abuse.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Comorbidity; Controlled

2006
Brain research and violent behavior. A summary and evaluation of the status of biomedical research on brain and aggressive violent behavior.
    Archives of neurology, 1974, Volume: 30, Issue:1

    Topics: Aggression; Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Bipolar Disorder; Bra

1974

Trials

3 trials available for disulfiram and Bipolar Disorder

ArticleYear
Psychotic spectrum disorders and alcohol abuse: a review of pharmacotherapeutic strategies and a report on the effectiveness of naltrexone and disulfiram.
    Schizophrenia bulletin, 2006, Volume: 32, Issue:4

    Topics: Adult; Alcohol Deterrents; Alcoholism; Bipolar Disorder; Combined Modality Therapy; Comorbidity; Dia

2006
Naltrexone and disulfiram in patients with alcohol dependence and current depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Alcohol Deterrents; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Comorbidity; Connecticu

2007
Can disulfiram potentiate the dexamethasone suppression test in depressive patients?
    Journal of affective disorders, 1993, Volume: 28, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Bipolar Disorder; Depressive Disorder; Dexamethasone; Disul

1993

Other Studies

13 other studies available for disulfiram and Bipolar Disorder

ArticleYear
[A serious "acetaldehyde syndrome" compounded by dopamine].
    Annales francaises d'anesthesie et de reanimation, 2011, Volume: 30, Issue:2

    Topics: Acetaldehyde; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Anti-Anxiety Agents; Antidepre

2011
[Exogenous mania following antabuse medication].
    Nordisk medicin, 1951, Jul-04, Volume: 46, Issue:27

    Topics: Bipolar Disorder; Disulfiram; Humans; Mental Disorders; Psychotic Disorders

1951
Manic episode with psychotic symptoms associated with high dose of disulfiram: a case report.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Alcohol Deterrents; Alcoholism; Bipolar Disorder; Disulfiram; Dose-Response Relationship, Dru

2007
Manic episode with psychosis following a lower than recommended dosage regimen of disulfiram.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Jan-01, Volume: 32, Issue:1

    Topics: Adult; Alcoholism; Bipolar Disorder; Disulfiram; Enzyme Inhibitors; Humans; Male; Psychotic Disorder

2008
Adverse interaction between disulfiram and marijuana: a case report.
    The American journal of psychiatry, 1983, Volume: 140, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Alcoholism; Bipolar Disorder; Disulfiram; Dronabinol; Drug In

1983
Control experiment in man on the sedative effect of disulfiram, an inhibitor of dopamine-beta-hydroxylase.
    Biological psychiatry, 1980, Volume: 15, Issue:4

    Topics: Bipolar Disorder; Disulfiram; Dopamine beta-Hydroxylase; Humans; Norepinephrine; Psychomotor Agitati

1980
Buspirone-induced mania: possible interaction with disulfiram.
    The British journal of psychiatry : the journal of mental science, 1991, Volume: 159

    Topics: Alcoholism; Bipolar Disorder; Buspirone; Disulfiram; Drug Therapy, Combination; Humans

1991
Carbamazepine-induced aseptic meningitis.
    Annals of internal medicine, 1990, Apr-15, Volume: 112, Issue:8

    Topics: Alcoholism; Bipolar Disorder; Carbamazepine; Disulfiram; Drug Interactions; Humans; Male; Meningitis

1990
Disulfiram and bipolar affective disorder.
    Journal of clinical psychopharmacology, 1987, Volume: 7, Issue:4

    Topics: Adult; Alcoholism; Bipolar Disorder; Disulfiram; Female; Humans

1987
Disulfiram and bipolar affective disorder: a case report.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:3

    Topics: Bipolar Disorder; Disulfiram; Drug Interactions; Ethanol; Humans; Male; Middle Aged

1986
[Sequellae of a disulfiram psychosis].
    Der Nervenarzt, 1969, Volume: 40, Issue:4

    Topics: Adult; Bipolar Disorder; Child, Preschool; Disulfiram; Family; Female; Forensic Medicine; Homicide;

1969
[Neurotoxic side-effects of disulfiram (Antabus) overdosage].
    Der Nervenarzt, 1970, Volume: 41, Issue:2

    Topics: Adult; Alcoholism; Beer; Bipolar Disorder; Brain; Central Nervous System; Disulfiram; Drug Antagonis

1970
Catecholamine metabolism of manic-depressive illness.
    Journal of psychiatric research, 1968, Volume: 6, Issue:3

    Topics: Antidepressive Agents; Bipolar Disorder; Calcium; Catecholamines; Creatinine; Disulfiram; Dopamine;

1968