disulfiram has been researched along with Alzheimer Disease in 1 studies
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reinhardt, S | 1 |
| Stoye, N | 1 |
| Luderer, M | 1 |
| Kiefer, F | 1 |
| Schmitt, U | 1 |
| Lieb, K | 1 |
| Endres, K | 1 |
1 trial available for disulfiram and Alzheimer Disease
| Article | Year |
|---|---|
Identification of disulfiram as a secretase-modulating compound with beneficial effects on Alzheimer's disease hallmarks.
Topics: ADAM10 Protein; Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Cell Line, Tumor; | 2018 |