disulfiram has been researched along with Alcoholic Intoxication in 40 studies
Alcoholic Intoxication: An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of a 42-year-old woman who presented with intractable hypotension and non-ST-elevation myocardial infarction as a result of a disulfiram-ethanol reaction." | 7.78 | Intractable hypotension and myocardial ischaemia induced by co-ingestion of ethanol and disulfiram. ( Desmet, W; Moreels, S; Neyrinck, A, 2012) |
| "We report a case of a 42-year-old woman who presented with intractable hypotension and non-ST-elevation myocardial infarction as a result of a disulfiram-ethanol reaction." | 3.78 | Intractable hypotension and myocardial ischaemia induced by co-ingestion of ethanol and disulfiram. ( Desmet, W; Moreels, S; Neyrinck, A, 2012) |
| "Severe hypotension resulting from a disulphiram-ethanol reaction was treated with adrenaline, the maximum dosage being 170 micrograms/kg/hour." | 1.28 | [High-dose adrenaline in the treatment of severe hypotensive crisis caused by a disulfiram-ethanol reaction]. ( Møller, LM; Pedersen, B, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (90.00) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 2 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amireche, N | 1 |
| Petit, JS | 1 |
| Bankole, E | 1 |
| Fournet-Fayard, A | 1 |
| Appriou, M | 1 |
| Leon, A | 1 |
| Moreels, S | 1 |
| Neyrinck, A | 1 |
| Desmet, W | 1 |
| MISSENARD, A | 1 |
| COIRAULT, R | 1 |
| JOLIVET, B | 1 |
| MARTENSEN-LARSEN, O | 1 |
| BERKA, V | 1 |
| KRATKY, A | 1 |
| ALHA, AR | 1 |
| HJELT, E | 1 |
| TAMMINEN, V | 1 |
| WINSHIP, GM | 1 |
| CASIER, H | 2 |
| MERLEVEDE, E | 2 |
| BRUNDIN, T | 1 |
| GREEN, W | 1 |
| PERMAN, ES | 2 |
| KAMIANOV, IM | 1 |
| LECOQ, R | 1 |
| CHAUCHARD, P | 1 |
| MAZOUE, H | 1 |
| McGregor, NR | 1 |
| Guerri, C | 1 |
| Grisolía, S | 1 |
| Chan, AW | 1 |
| Rimailho, A | 1 |
| Riou, B | 1 |
| Richard, C | 1 |
| Auzépy, P | 1 |
| Grange, JF | 1 |
| Parantainen, J | 1 |
| Olson, E | 1 |
| McEnrue, J | 1 |
| Greenbaum, DM | 1 |
| Tennant, FS | 1 |
| Bueno, F | 1 |
| Mezey, E | 1 |
| Seixas, FA | 1 |
| Møller, LM | 1 |
| Pedersen, B | 1 |
| Liskow, BI | 1 |
| Goodwin, DW | 1 |
| Kirubakaran, V | 1 |
| Faiman, MD | 1 |
| Liskow, B | 1 |
| Mayfield, D | 1 |
| Böhme, K | 1 |
| Piltz, E | 1 |
| Kissin, B | 1 |
| Gross, MM | 1 |
| Graveleau, J | 1 |
| Battegay, R | 1 |
| Rauchfleisch, U | 1 |
| Lereboullet, J | 1 |
| Blum, K | 1 |
| Calhoun, W | 1 |
| Merritt, J | 1 |
| Wallace, JE | 1 |
| Ezrielev, GI | 1 |
| Rosenberg, CM | 1 |
| Chaftez, ME | 1 |
| Cahill, CA | 1 |
| Pogády, J | 1 |
| Turcek, M | 1 |
| Cerven, J | 1 |
| Hudáková, G | 1 |
| Müncnerová, L | 1 |
| Breen, KJ | 1 |
| Shaw, J | 1 |
| Levinson, JD | 1 |
| Schenker, S | 1 |
| Shpinetskiĭ, RV | 1 |
| Wolański, A | 1 |
| Kowalski, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acamprosate for Central Nervous System Hyperexcitability and Neuroadaptation in Alcohol Withdrawal[NCT00106106] | Phase 2 | 56 participants (Actual) | Interventional | 2005-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 25
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.350375 |
| Acamprosate | 1.166667 |
The ratio of glutamate to creatine was determined using magnetic resonance spectroscopy (MRS), a technique that complements magnetic resonance imaging (MRI). MRS is used to determine the concentration of brain metabolites, such as glutamate, in brain tissue. MRS utilizes a magnetic field to look at magnetic nuclei, which absorb and re-emit electromagnetic energy in the presence of the magnetic field. By looking at the peaks in the resultant spectra the structure and concentration of metabolites can be determined. (NCT00106106)
Timeframe: Day 4
| Intervention | Ratio of glutamate to creatine (Mean) |
|---|---|
| Placebo | 1.256772 |
| Acamprosate | 1.294178 |
6 reviews available for disulfiram and Alcoholic Intoxication
| Article | Year |
|---|---|
Pueraria lobata (Kudzu root) hangover remedies and acetaldehyde-associated neoplasm risk.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Aldehyd | 2007 |
Effects of combined alcohol and benzodiazepine: a review.
Topics: Abnormalities, Drug-Induced; Accidents, Traffic; Adolescent; Adult; Age Factors; Alcohol Drinking; A | 1984 |
Prostaglandins in alcohol intolerance and hangover.
Topics: Alcoholic Intoxication; Animals; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Humans; Mig | 1983 |
Pharmacological treatment of alcohol intoxication, withdrawal and dependence: a critical review.
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Antidepressive Agents, Tricyclic; Bromocript | 1987 |
[Pathogenesis and therapy of alcoholism].
Topics: Adolescent; Adult; Affective Symptoms; Age Factors; Alcoholic Intoxication; Alcoholism; Disulfiram; | 1973 |
Drugs in the treatment of alcoholism.
Topics: Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Amitriptyline; Antidepressive Agents; Chlord | 1967 |
1 trial available for disulfiram and Alcoholic Intoxication
| Article | Year |
|---|---|
Drug maintenance in the outpatient treatment of chronic alcoholism.
Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Automobile Driving; Boston; Chlordiazep | 1974 |
33 other studies available for disulfiram and Alcoholic Intoxication
| Article | Year |
|---|---|
[A serious "acetaldehyde syndrome" compounded by dopamine].
Topics: Acetaldehyde; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Anti-Anxiety Agents; Antidepre | 2011 |
Intractable hypotension and myocardial ischaemia induced by co-ingestion of ethanol and disulfiram.
Topics: Adult; Alcohol Deterrents; Alcoholic Intoxication; Alcoholism; Disulfiram; Electrocardiography; Fema | 2012 |
[Complication of disulfiram therapy of alcoholic intoxication].
Topics: Alcoholic Intoxication; Disulfiram; Humans; Mental Disorders | 1955 |
The treatment of acute alcohol intoxication with antihistamine, disulfiram, fructose (honey) and vitamin B6.
Topics: Alcoholic Intoxication; Alcoholism; Anti-Allergic Agents; Disulfiram; Fructose; Histamine H1 Antagon | 1956 |
[Antabuse and the level of volatile substances in blood].
Topics: Alcoholic Intoxication; Disulfiram; Ethanol; Humans | 1957 |
Disulfiram-alcohol intoxication; investigation of five fatal cases and the chemical determination of disulfiram and blood acetaldehyde.
Topics: Acetaldehyde; Alcoholic Intoxication; Disulfiram; Humans | 1957 |
Disulfiram as an aid to psychotherapy in the case of an impulsive drinker.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Disulfiram; Humans; Psychotherapy | 1957 |
[On the mechanism of the disulfiram-ethanol intoxication symptoms].
Topics: Alcoholic Intoxication; Disulfiram; Ethanol; Humans | 1962 |
Decrease in plasma potassium during the disulfiram-ethanol reaction in rabbits.
Topics: Alcoholic Intoxication; Animals; Disulfiram; Ethanol; Lagomorpha; Potassium; Rabbits | 1962 |
On the mechanism of the disulfiram-ethanol intoxication symptoms.
Topics: Alcoholic Intoxication; Disulfiram; Ethanol; Humans | 1962 |
[THE USE OF SODIUM NICOTINATE FOR IMITATION OF THE ANTABUSE-ALCOHOLIC TEST DURING TREATMENT OF PATIENTS WITH CHRONIC ALCOHOLISM].
Topics: Alcoholic Intoxication; Alcoholism; Anions; Disulfiram; Humans; Ions; Niacin; Nicotinic Acids; Sodiu | 1963 |
[Chronaximetric study of the experimental behavior of some psycholeptic agents on the effects of alcohol (with and without associated action of disulfiram)].
Topics: Alcoholic Intoxication; Disulfiram; Ethanol; Tranquilizing Agents | 1962 |
Studies on the antabuse--alcohol reaction in rabbits.
Topics: Alcoholic Intoxication; Animals; Disulfiram; Ethanol; Lagomorpha; Rabbits | 1962 |
Changes in glutathione in acute and chronic alcohol intoxication.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Disulfiram; gamma-Glutamyltransferase; Glutathione; Hum | 1980 |
[Myocardial infarction after voluntary poisoning with disulfiram and alcohol].
Topics: Adult; Alcoholic Intoxication; Coronary Vasospasm; Disulfiram; Humans; Male; Myocardial Infarction | 1984 |
[Nursing care and supervision of alcoholics in the institutional environment].
Topics: Alcoholic Intoxication; Alcoholism; Disulfiram; Hospitals, Psychiatric; Humans; Hypnotics and Sedati | 1980 |
Clinical aspects of drug intoxication: alcohols and miscellaneous agents.
Topics: 1-Propanol; Alcoholic Intoxication; Cocaine; Disulfiram; Ethanol; Ethylene Glycols; Humans; Lithium; | 1983 |
Use of a pocket-size breath analyzer in the detection and treatment of alcohol misuse.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Ambulatory Care; Breath Tests; Disulfiram; Eth | 1979 |
[Therapy of alcoholism].
Topics: Acute Disease; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcoholism; Avitaminosis; Chroni | 1976 |
Alcohol and its drug interactions.
Topics: Alcoholic Intoxication; Alcoholism; Barbiturates; Brain; Depression, Chemical; Disulfiram; Dose-Resp | 1975 |
[High-dose adrenaline in the treatment of severe hypotensive crisis caused by a disulfiram-ethanol reaction].
Topics: Alcoholic Intoxication; Disulfiram; Epinephrine; Female; Humans; Hypotension; Middle Aged; Shock; Su | 1990 |
Plasma measurements of disulfiram and its metabolites in a case of severe disulfiram-ethanol reaction.
Topics: Adult; Alcoholic Intoxication; Disulfiram; Drug Interactions; Humans; Male | 1986 |
[Is disulfiram treatment still indicated today? (author's transl)].
Topics: Adolescent; Adult; Age Factors; Aged; Alcoholic Intoxication; Alcoholism; Disulfiram; Drug Tolerance | 1974 |
Drug therapy in alcoholism.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Antidepressive Agents; Anxiety; Carbamates; Chlordiazepox | 1970 |
[Peripheral neuropathies caused by disulfiram (antabuse)].
Topics: Alcoholic Intoxication; Deglutition Disorders; Disulfiram; Ethanol; Facial Paralysis; Female; Humans | 1972 |
[Adverse effects of disulfiram. Undetected disulfiram-alcohol reactions].
Topics: Adult; Alcoholic Intoxication; Alcoholism; Cognition Disorders; Disulfiram; Drug Interactions; Ethan | 1972 |
L-DOPA: effect on ethanol narcosis and brain biogenic amines in mice.
Topics: Alcoholic Intoxication; Animals; Biogenic Amines; Brain Chemistry; Dihydroxyphenylalanine; Disulfira | 1973 |
[Acetaldehyde and alcoholism. The pharmacogenesis of the teturam-alcohol reaction and its control by way of binding acetaldehyde with sodium metabisulfite].
Topics: Acetaldehyde; Adult; Alcoholic Intoxication; Alcoholism; Animals; Disulfiram; Humans; Mice; Sulfites | 1973 |
Safety of disulfiram.
Topics: Alcoholic Intoxication; Alcoholism; Disulfiram; Female; Humans; Male; Middle Aged | 1972 |
[Etiopathogenesis of disulfiram-induced psychoses].
Topics: Acidosis; Alcoholic Intoxication; Disulfiram; Humans | 1971 |
The acute effect of alcohol on hepatic coenzyme A and acetyl CoA concentrations.
Topics: Alcoholic Intoxication; Animals; Carboxy-Lyases; Chemical and Drug Induced Liver Injury; Coenzyme A; | 1971 |
[Some symptoms of Antabuse poisoning and Antabuse-alcoholic intoxication and emergency medical measures in these cases].
Topics: Alcoholic Intoxication; Disulfiram; First Aid; Humans; Nursing | 1966 |
[Antabuse-like effects of chloropropamide].
Topics: Adult; Aged; Alcoholic Intoxication; Chlorpropamide; Diabetes Mellitus; Disulfiram; Drug Synergism; | 1966 |