disulfiram has been researched along with Alcohol Drinking in 110 studies
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
Excerpt | Relevance | Reference |
---|---|---|
"We conducted a controlled, blinded, multicenter study of disulfiram treatment of alcoholism in 605 men randomly assigned to 250 mg of disulfiram (202 men); 1 mg of disulfiram (204 men), a control for the threat of the disulfiram-ethanol reaction; or no disulfiram (199 men), a control for the counseling that all received." | 9.06 | Disulfiram treatment of alcoholism. A Veterans Administration cooperative study. ( Branchey, L; Brightwell, DR; Derman, RM; Emrick, CD; Fuller, RK; Iber, FL; James, KE; Lacoursiere, RB; Lee, KK; Lowenstam, I, 1986) |
"To describe the potential use of disulfiram in treating acetonitrile poisoning in a human clinical case and to further study its effect in human liver microsomes in vitro." | 7.83 | Disulfiram inhibition of cyanide formation after acetonitrile poisoning. ( Benoit, D; Boussery, K; Buylaert, W; Colin, P; De Paepe, P; De Smet, J; Decavele, AS; Depuydt, P; Stove, C; Van Bocxlaer, J; Verstraete, A, 2016) |
"Of 60 depressed alcoholics who completed an open trial of imipramine, 27 (45%) responded with improvement in both mood and drinking behavior, and eight (13%) responded after further dosage increases or treatment with disulfiram." | 6.67 | Imipramine treatment of alcoholism with comorbid depression. ( Harrison, W; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Stewart, JP; Tricamo, E, 1993) |
"The Disulfiram Assurance treatment resulted in almost total sobriety for married or (cohabitating) clients but had little benefit for the single ones." | 5.26 | Alcoholism treatment by disulfiram and community reinforcement therapy. ( Azrin, NH; Godley, M; Meyers, R; Sisson, RW, 1982) |
"We conducted a controlled, blinded, multicenter study of disulfiram treatment of alcoholism in 605 men randomly assigned to 250 mg of disulfiram (202 men); 1 mg of disulfiram (204 men), a control for the threat of the disulfiram-ethanol reaction; or no disulfiram (199 men), a control for the counseling that all received." | 5.06 | Disulfiram treatment of alcoholism. A Veterans Administration cooperative study. ( Branchey, L; Brightwell, DR; Derman, RM; Emrick, CD; Fuller, RK; Iber, FL; James, KE; Lacoursiere, RB; Lee, KK; Lowenstam, I, 1986) |
" Specific prenatal exposures were identified at different times in the first trimester of pregnancy: crack cocaine, marijuana, disulfiram, heavy ethanol exposure, and cigarettes." | 4.79 | Prenatal exposure to disulfiram implicated in the cause of malformations in discordant monozygotic twins. ( Aylsworth, AS; Callanan, NP; Farber, RA; Reitnauer, PJ, 1997) |
"To describe the potential use of disulfiram in treating acetonitrile poisoning in a human clinical case and to further study its effect in human liver microsomes in vitro." | 3.83 | Disulfiram inhibition of cyanide formation after acetonitrile poisoning. ( Benoit, D; Boussery, K; Buylaert, W; Colin, P; De Paepe, P; De Smet, J; Decavele, AS; Depuydt, P; Stove, C; Van Bocxlaer, J; Verstraete, A, 2016) |
"We investigated the effect of direct administration of acetaldehyde on behavioral measures of anxiety and on hormonal markers of stress in mice." | 3.78 | Anxiogenic and stress-inducing effects of peripherally administered acetaldehyde in mice: similarities with the disulfiram-ethanol reaction. ( Aragon, CM; Correa, M; Escrig, MA; Pardo, M, 2012) |
"Disulfiram, an inhibitor of aldehyde dehydrogenase used in the treatment of alcoholism, is an effective medication when its intake is supervised by a third person." | 3.74 | Tolerance to disulfiram induced by chronic alcohol intake in the rat. ( Israel, Y; Quintanilla, ME; Tampier, L, 2008) |
"Disulfiram has been widely used as an adjunct in the treatment of alcoholism and has relatively few side effects." | 3.67 | Disulfiram hepatotoxicity: case report. ( Black, JL; Richardson, JW, 1985) |
"A total of 348 consecutive primary alcoholics entering an alcoholism treatment program comprised Group 1 (172 men who were offered disulfiram and agreed to take it) and Group 2 (176 who were eligible to take the drug but refused)." | 3.67 | A one-year follow-up of men alcoholics given disulfiram. ( Schuckit, MA, 1985) |
"This paper discusses superego fixations and regressions that predispose to and are caused by alcoholism." | 3.65 | Superego factors in alcoholics. ( Frances, A; Gale, L, 1975) |
"Disulfiram (DSF) is a well-known anti-alcohol agent that inhibits aldehyde dehydrogenase and results in extreme 'hangover' symptoms when consumed with alcohol." | 2.72 | Advantages and disadvantages of disulfiram coadministered with popular addictive substances. ( Kleczkowska, P; Sulejczak, D; Zaremba, M, 2021) |
"Of 60 depressed alcoholics who completed an open trial of imipramine, 27 (45%) responded with improvement in both mood and drinking behavior, and eight (13%) responded after further dosage increases or treatment with disulfiram." | 2.67 | Imipramine treatment of alcoholism with comorbid depression. ( Harrison, W; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Stewart, JP; Tricamo, E, 1993) |
" Although all groups showed an increase in sobriety following implantation, there was no significant dose-response relationship." | 2.65 | Disulfiram implantation: a dose response trial. ( Blanchard, R; Davidson, W; Maini, K; McRae, L; Wilson, A, 1984) |
"Disulfiram was administered at a dosage of 125 mg/day for seven days and 250 mg/day thereafter for 36 weeks." | 2.65 | Use of disulfiram for alcoholics in methadone maintenance programs. A Veterans Administration Cooperative Study. ( Charuvastra, VC; Ling, W; O'Brien, CP; Weiss, DG, 1983) |
"Naltrexone is effective to treat alcohol dependence (decreased length and frequency of drinking bouts), but its severe side effects, including withdrawal symptoms, are difficult to overcome." | 2.50 | Alcohol use disorders and current pharmacological therapies: the role of GABA(A) receptors. ( Liang, J; Olsen, RW, 2014) |
"Disulfiram is an adjunct in the treatment of alcohol use disorders, but case reports indicate that disulfiram ethanol reactions are not always recognized in the emergency department." | 1.56 | Recognition of a disulfiram ethanol reaction in the emergency department is not always straightforward. ( Buylaert, W; Chys, S; De Paepe, P; Desmet, T; Huys, L; Segher, K; Steen, E, 2020) |
"Disulfiram acts as an ACD blocker." | 1.34 | Are disulfiram-like reactions associated with abacavir-containing antiretroviral regimens in clinical practice? ( Barber, TJ; Mackie, NE; Marett, B; Portsmouth, S; Waldron, S; Weston, R; Winston, A, 2007) |
"Daidzin treatment (150 mg/kg per day i." | 1.29 | Daidzin suppresses ethanol consumption by Syrian golden hamsters without blocking acetaldehyde metabolism. ( Keung, WM; Kunze, L; Lazo, O; Vallee, BL, 1995) |
"Daidzein was less potent and a higher dose (230 mg/kg/day) was required to produce similar effect." | 1.29 | Therapeutic lessons from traditional Oriental medicine to contemporary Occidental pharmacology. ( Keung, WM; Vallee, BL, 1994) |
" Long-term use was significantly related to a favourable drinking outcome during 2 years subsequent to treatment compared with short-term use." | 1.28 | Long-term use of aversive drugs in outpatient alcoholism treatment. ( Berglund, M; Ojehagen, A; Skjaerris, A, 1991) |
"The Disulfiram Assurance treatment resulted in almost total sobriety for married or (cohabitating) clients but had little benefit for the single ones." | 1.26 | Alcoholism treatment by disulfiram and community reinforcement therapy. ( Azrin, NH; Godley, M; Meyers, R; Sisson, RW, 1982) |
"Moderate withdrawal symptoms in susceptible patients require substitution medication which can be monitored on an outpatient basis." | 1.26 | Ambulatory management in alcoholism. ( Bort, RF, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 70 (63.64) | 18.7374 |
1990's | 14 (12.73) | 18.2507 |
2000's | 12 (10.91) | 29.6817 |
2010's | 10 (9.09) | 24.3611 |
2020's | 4 (3.64) | 2.80 |
Authors | Studies |
---|---|
Antonelli, M | 1 |
Sestito, L | 1 |
Tarli, C | 1 |
Addolorato, G | 1 |
Hyland, CJ | 1 |
McDowell, MJ | 1 |
Bain, PA | 1 |
Huskamp, HA | 1 |
Busch, AB | 1 |
Segher, K | 1 |
Huys, L | 1 |
Desmet, T | 1 |
Steen, E | 1 |
Chys, S | 1 |
Buylaert, W | 2 |
De Paepe, P | 2 |
Kleczkowska, P | 1 |
Sulejczak, D | 1 |
Zaremba, M | 1 |
Liu, L | 1 |
Huang, C | 1 |
Bian, Y | 1 |
Miao, L | 1 |
An, S | 1 |
Li, X | 1 |
Tang, M | 1 |
Yan, S | 1 |
Yang, F | 1 |
Zhu, X | 1 |
Chen, Z | 1 |
Liu, Q | 1 |
O'Malley, SS | 1 |
O'Connor, PG | 1 |
Liang, J | 1 |
Olsen, RW | 1 |
Colin, P | 1 |
Depuydt, P | 1 |
Decavele, AS | 1 |
De Smet, J | 1 |
Boussery, K | 1 |
Stove, C | 1 |
Benoit, D | 1 |
Verstraete, A | 1 |
Van Bocxlaer, J | 1 |
Garbutt, JC | 1 |
de Haro, L | 1 |
Skinner, MD | 1 |
Coudert, M | 1 |
Berlin, I | 1 |
Passeri, E | 1 |
Michel, L | 1 |
Aubin, HJ | 1 |
Oliveto, A | 1 |
Poling, J | 1 |
Mancino, MJ | 1 |
Feldman, Z | 1 |
Cubells, JF | 1 |
Pruzinsky, R | 1 |
Gonsai, K | 1 |
Cargile, C | 1 |
Sofuoglu, M | 1 |
Chopra, MP | 1 |
Gonzalez-Haddad, G | 1 |
Carroll, KM | 2 |
Kosten, TR | 1 |
Escrig, MA | 1 |
Pardo, M | 1 |
Aragon, CM | 1 |
Correa, M | 1 |
Nich, C | 1 |
Shi, JM | 1 |
Eagan, D | 1 |
Ball, SA | 1 |
Tampier, L | 3 |
Quintanilla, ME | 3 |
WINSHIP, GM | 1 |
Lee, TH | 1 |
Kenna, GA | 1 |
McGeary, JE | 1 |
Swift, RM | 1 |
Morales-Molina, JA | 1 |
Mateu-de Antonio, J | 1 |
Grau, S | 1 |
Ferrández, O | 1 |
Bilbeny, N | 1 |
Contreras, S | 1 |
Font, M | 1 |
Paeile, C | 1 |
García, H | 1 |
Batel, P | 1 |
Balester-Mouret, S | 1 |
Nava, F | 1 |
Premi, S | 1 |
Manzato, E | 1 |
Lucchini, A | 1 |
Barber, TJ | 1 |
Marett, B | 1 |
Waldron, S | 1 |
Portsmouth, S | 1 |
Mackie, NE | 1 |
Weston, R | 1 |
Winston, A | 1 |
Israel, Y | 1 |
Reeves, DS | 1 |
Davies, AJ | 1 |
MacGregor, GA | 1 |
Gluud, C | 1 |
Andersen, I | 1 |
Dietrichson, O | 1 |
Gluud, B | 1 |
Jacobsen, A | 1 |
Juhl, E | 1 |
Chan, AW | 1 |
Wilson, A | 3 |
Blanchard, R | 1 |
Davidson, W | 1 |
McRae, L | 1 |
Maini, K | 1 |
Smith, BR | 1 |
LeFrock, JL | 1 |
Fuller, R | 1 |
Roth, H | 1 |
Long, S | 1 |
Brien, JF | 1 |
Loomis, CW | 1 |
Ling, W | 1 |
Weiss, DG | 1 |
Charuvastra, VC | 1 |
O'Brien, CP | 1 |
O'Farrell, TJ | 3 |
Cutter, HS | 1 |
Poikolainen, K | 1 |
Nirenberg, TD | 1 |
Sobell, LC | 1 |
Ersner-Hershfield, S | 1 |
Cellucci, AJ | 1 |
Kuribara, H | 1 |
Higashida, A | 1 |
Tadokoro, S | 1 |
Lyons, JP | 1 |
Welte, JW | 1 |
Brown, J | 1 |
Sokolow, L | 1 |
Hynes, G | 1 |
Phillips, S | 1 |
Cragg, B | 1 |
Veech, RL | 1 |
Felver, ME | 1 |
Lakshmanan, MR | 1 |
Huang, MT | 1 |
Wolf, S | 1 |
Sellers, EM | 2 |
Naranjo, CA | 2 |
Peachey, JE | 1 |
Azrin, NH | 1 |
Sisson, RW | 1 |
Meyers, R | 1 |
Godley, M | 1 |
Plouvier, B | 1 |
Lemoine, X | 1 |
De Coninck, P | 1 |
Baclet, JL | 1 |
François, M | 1 |
Keung, WM | 2 |
Lazo, O | 1 |
Kunze, L | 1 |
Vallee, BL | 2 |
Becker, J | 1 |
Desel, H | 1 |
Schuster, HP | 1 |
Kahl, GF | 1 |
Nunes, EV | 1 |
McGrath, PJ | 1 |
Quitkin, FM | 1 |
Stewart, JP | 1 |
Harrison, W | 1 |
Tricamo, E | 1 |
Ocepek-Welikson, K | 1 |
Chick, J | 1 |
He, XX | 1 |
Nebert, DW | 1 |
Vasiliou, V | 1 |
Zhu, H | 1 |
Shertzer, HG | 1 |
Reitnauer, PJ | 1 |
Callanan, NP | 1 |
Farber, RA | 1 |
Aylsworth, AS | 1 |
Bort, RF | 1 |
Ritson, EB | 1 |
Kitson, TM | 1 |
Kwentus, J | 1 |
Major, LF | 1 |
Tennant, FS | 1 |
Davidson, WJ | 1 |
White, J | 1 |
Lewison, EF | 1 |
Bigelow, G | 2 |
Strickler, D | 1 |
Liebson, I | 2 |
Griffiths, R | 1 |
Amit, Z | 2 |
Levitan, DE | 1 |
Lindros, KO | 1 |
Meade, RG | 1 |
Corcoran, ME | 1 |
Gale, L | 1 |
Frances, A | 1 |
Tønnesen, H | 1 |
Kaiser, AH | 1 |
Nielsen, BB | 1 |
Pedersen, AE | 1 |
Johnsen, J | 2 |
Mørland, J | 1 |
Ojehagen, A | 1 |
Skjaerris, A | 1 |
Berglund, M | 1 |
Marcon, G | 1 |
Spolaor, A | 1 |
Scevola, M | 1 |
Zolli, M | 1 |
Carlassara, GB | 1 |
Kranzler, HR | 1 |
Dolinsky, Z | 1 |
Kaplan, RF | 1 |
Liskow, B | 1 |
Nickel, E | 1 |
Tunley, N | 1 |
Powell, BJ | 2 |
Penick, EC | 2 |
Dahlgren, L | 1 |
Willander, A | 1 |
Preskorn, SH | 1 |
Goodwin, DW | 1 |
Read, MR | 1 |
Ludwig, AM | 2 |
Lawrin, MO | 1 |
Chick, JD | 1 |
Critchfield, GC | 1 |
Eddy, DM | 1 |
Langenbucher, J | 1 |
Fuller, RK | 1 |
Branchey, L | 1 |
Brightwell, DR | 1 |
Derman, RM | 1 |
Emrick, CD | 1 |
Iber, FL | 1 |
James, KE | 1 |
Lacoursiere, RB | 1 |
Lee, KK | 1 |
Lowenstam, I | 1 |
Duckert, F | 1 |
Foy, A | 1 |
Bayog, RD | 1 |
Mardones, J | 1 |
Algar, EM | 1 |
Holmes, RS | 1 |
Black, JL | 1 |
Richardson, JW | 1 |
Schuckit, MA | 1 |
Bean-Bayog, M | 1 |
Ewing, JA | 2 |
Mottin, JL | 1 |
Kraemer, RJ | 1 |
Deitrich, RA | 1 |
Roos, BE | 1 |
Wilson, CW | 1 |
Flamer, R | 1 |
Choi, SY | 1 |
Kline, JA | 1 |
Roberts, AC | 1 |
Rosenberg, CM | 2 |
von Keyserlingk, H | 1 |
Gorecki, T | 1 |
Konarska, L | 1 |
Merry, J | 1 |
Hussain, MZ | 1 |
Harinath, M | 1 |
Shore, JH | 1 |
Von Fumetti, B | 1 |
Mayer, J | 1 |
Myerson, DJ | 1 |
Kimmel, ME | 1 |
Lubetkin, BS | 1 |
Rivers, PC | 1 |
Ritson, B | 1 |
Savard, RJ | 1 |
Ludwig, A | 1 |
Levine, J | 1 |
Stark, L | 1 |
Lazar, R | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Does the Threat of an Aversive Reaction Affect Craving of Alcohol During Cue Exposure in Alcohol Dependent Patients?[NCT00372749] | 30 participants (Actual) | Interventional | 2006-10-31 | Completed | |||
Maximizing the Efficacy of Cognitive Behavioral Therapy With Medication and Contingency Management[NCT00350870] | Phase 1 | 181 participants (Actual) | Interventional | 2005-04-30 | Completed | ||
Alcohol Based Hand Sanitizer: Can Frequent Use Cause an Elevated Blood Alcohol Level?[NCT00297908] | 5 participants | Observational | 2006-02-28 | Completed | |||
Phase II Open Labeled Trial of Disulfiram With Copper in Metastatic Breast Cancer[NCT03323346] | Phase 2 | 150 participants (Anticipated) | Interventional | 2017-09-29 | Recruiting | ||
Piloting Deposit Contracts to Increase Accessibility of a Contingency Management Intervention to Reduce Problematic Drinking[NCT05837611] | 80 participants (Anticipated) | Interventional | 2022-06-10 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Self-reports of substance use will be documented at each contact via the Substance Use Calendar. Similar to the Form-90 and the Time Line Follow-Back, which have been shown to be reliable and valid instruments for monitoring substance use and other outcomes in longitudinal studies202-204, the Substance Use Calendar allows a flexible, continuous evaluation of substance use on a daily basis. (NCT00350870)
Timeframe: 12 weeks
Intervention | percentage of days abstinent (Mean) |
---|---|
Placebo | 72.2 |
Disulfiram | 79.2 |
Placebo Plus Contingency Management | 91.1 |
Disulfiram Plus Contingency Management | 69.6 |
We will use the Roche onsite TESTCUP system for detection of cocaine, methamphetamine, THC, benzodiazepenes, and opioids. (NCT00350870)
Timeframe: 12 weeks
Intervention | percentage of negative urines (Mean) |
---|---|
Placebo | 17.9 |
Disulfiram | 30.1 |
Placebo Plus Contingency Management | 53 |
Disulfiram Plus Contingency Management | 42.6 |
17 reviews available for disulfiram and Alcohol Drinking
Article | Year |
---|---|
Perspectives on the pharmacological management of alcohol use disorder: Are the approved medications effective?
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Disulfiram; Humans; Naltrexone | 2022 |
Integration of pharmacotherapy for alcohol use disorder treatment in primary care settings: A scoping review.
Topics: Acamprosate; Adolescent; Alcohol Drinking; Alcoholism; Disulfiram; Humans; Naltrexone; Primary Healt | 2023 |
Advantages and disadvantages of disulfiram coadministered with popular addictive substances.
Topics: Acetaldehyde Dehydrogenase Inhibitors; Alcohol Drinking; Alcoholism; Animals; Disulfiram; Drug Inter | 2021 |
Medications for unhealthy alcohol use: across the spectrum.
Topics: Acamprosate; Alcohol Drinking; Alcoholism; Animals; Disulfiram; Dopamine Agents; Fructose; Humans; N | 2011 |
Alcohol use disorders and current pharmacological therapies: the role of GABA(A) receptors.
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Benzodiazepines; Disulfiram; | 2014 |
The state of pharmacotherapy for the treatment of alcohol dependence.
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Baclofen; Delayed-Action Preparations | 2009 |
Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, part 1.
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Animals; Clinical Tria | 2004 |
Effects of combined alcohol and benzodiazepine: a review.
Topics: Abnormalities, Drug-Induced; Accidents, Traffic; Adolescent; Adult; Age Factors; Alcohol Drinking; A | 1984 |
Pharmacology of acetaldehyde.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Behavior; Biogenic Amines; Biotransformation; Brain; Brain | 1983 |
Drug therapy: Drugs to decrease alcohol consumption.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Antidepressive Agents; Benzodiazepin | 1981 |
Prenatal exposure to disulfiram implicated in the cause of malformations in discordant monozygotic twins.
Topics: Abnormalities, Drug-Induced; Adult; Alcohol Deterrents; Alcohol Drinking; Cleft Palate; Disulfiram; | 1997 |
The disulfiram--ethanol reaction: a review.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Disulfiram; Dopamine beta-Hydroxylase; Enzyme I | 1977 |
Disulfiram in the treatment of alcoholism; a review.
Topics: Alcohol Drinking; Alcoholism; Biotransformation; Brain; Disulfiram; Dose-Response Relationship, Drug | 1979 |
The lateral hypothalamus, catecholamines and ethanol self-administration in rats.
Topics: Alcohol Drinking; Aldehydes; Animals; Catecholamines; Cyanides; Disulfiram; Dopamine beta-Hydroxylas | 1975 |
Modulation of ethanol intake by serotonin uptake inhibitors.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Brain; Citalopram; Disulfiram; Dopamine; Humans | 1986 |
Drug-induced attenuation of alcohol consumption. A review and evaluation of claimed, potential or current therapies.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Aversive Therapy; Conditioning, Classical; Conditi | 1973 |
The pharmacological actions of alcohol in relation to nutrition.
Topics: Absorption; Adult; Alcohol Drinking; Animals; Barbiturates; Behavior, Animal; Diffusion; Disulfiram; | 1972 |
15 trials available for disulfiram and Alcohol Drinking
Article | Year |
---|---|
Effect of the threat of a disulfiram-ethanol reaction on cue reactivity in alcoholics.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Autonomic Nervous System; Blood Pressure; Conditioning, P | 2010 |
Randomized, double blind, placebo-controlled trial of disulfiram for the treatment of cocaine dependence in methadone-stabilized patients.
Topics: Adult; Alcohol Drinking; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Disulfira | 2011 |
Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial.
Topics: Adult; Alcohol Deterrents; Alcohol Drinking; Cocaine-Related Disorders; Counseling; Demography; Diag | 2012 |
Comparing treatments of alcoholism on craving and biochemical measures of alcohol consumptionst.
Topics: Adult; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Biomarkers; Disulfiram; Female; Humans; Mal | 2006 |
Disulfiram implantation: a dose response trial.
Topics: Adult; Alcohol Drinking; Alcoholism; Disulfiram; Dose-Response Relationship, Drug; Drug Implants; Dr | 1984 |
Compliance with disulfiram treatment of alcoholism.
Topics: Adult; Alcohol Drinking; Alcoholism; Clinical Trials as Topic; Disulfiram; Follow-Up Studies; Humans | 1983 |
Use of disulfiram for alcoholics in methadone maintenance programs. A Veterans Administration Cooperative Study.
Topics: Adult; Alcohol Drinking; Alcoholism; Clinical Trials as Topic; Disulfiram; Double-Blind Method; Drug | 1983 |
Imipramine treatment of alcoholism with comorbid depression.
Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Comorbidity; Depressive Disorder; Disulfiram; Dose-Resp | 1993 |
Patient management in disulfiram implant therapy.
Topics: Acetaldehyde; Administration, Oral; Alcohol Drinking; Alcoholism; Disulfiram; Drug Implants; Humans; | 1979 |
Disulfiram implantation: placebo, psychological deterrent, and pharmacological deterrent effects.
Topics: Alcohol Drinking; Alcoholism; Clinical Trials as Topic; Disulfiram; Drug Implants; Ethanol; Gastroin | 1976 |
Disulfiram implant: a double-blind placebo controlled follow-up on treatment outcome.
Topics: Acetaldehyde; Adult; Aged; Alcohol Drinking; Alcoholism; Disulfiram; Double-Blind Method; Drug Impla | 1991 |
Comparison of three outpatient treatment interventions: a twelve-month follow-up of men alcoholics.
Topics: Adult; Aftercare; Alcohol Drinking; Alcoholism; Ambulatory Care; Combined Modality Therapy; Disulfir | 1985 |
A confidence profile analysis of the effectiveness of disulfiram in the treatment of chronic alcoholism.
Topics: Alcohol Drinking; Alcoholism; Clinical Trials as Topic; Data Interpretation, Statistical; Disulfiram | 1987 |
Disulfiram treatment of alcoholism. A Veterans Administration cooperative study.
Topics: Actuarial Analysis; Alcohol Drinking; Alcoholism; Clinical Trials as Topic; Combined Modality Therap | 1986 |
Drug maintenance in the outpatient treatment of chronic alcoholism.
Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Automobile Driving; Boston; Chlordiazep | 1974 |
78 other studies available for disulfiram and Alcohol Drinking
Article | Year |
---|---|
Recognition of a disulfiram ethanol reaction in the emergency department is not always straightforward.
Topics: Acetaldehyde; Adult; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Disulfiram; Drug Interactions | 2020 |
GC-MS based metabolomics of CSF and blood serum: Metabolic phenotype for a rat model of cefoperazone-induced disulfiram-like reaction.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Anti-Bacterial Agents; Cefoperazone; Disulfiram; Etha | 2017 |
Functional duality of ethanol on cancer.
Topics: Acetic Acid; Acids; Alcohol Drinking; Alcoholism; Calcium Oxalate; Disulfiram; Ethanol; Humans; Hydr | 2019 |
KASL clinical practice guidelines: management of alcoholic liver disease.
Topics: Alcohol Abstinence; Alcohol Drinking; Alcohol-Related Disorders; Baclofen; Disulfiram; Fatty Liver, | 2013 |
Disulfiram inhibition of cyanide formation after acetonitrile poisoning.
Topics: Acetonitriles; Acidosis, Lactic; Adult; Alcohol Drinking; Aldicarb; Biomarkers; Blood Alcohol Conten | 2016 |
Disulfiram-like syndrome after hydrogen cyanamide professional skin exposure: two case reports in France.
Topics: Actinidia; Agriculture; Alcohol Drinking; Cyanamide; Disulfiram; Drug Interactions; Flushing; France | 2009 |
Alcohol dependence: after the withdrawal phase. Long-term abstinence: better health and psychosocial status. Psychosocial support for a chronic disorder. Some drugs are useful adjuncts to medical support.
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcohol-Related Disorders; Alcoholics; Alcoholism | 2009 |
Anxiogenic and stress-inducing effects of peripherally administered acetaldehyde in mice: similarities with the disulfiram-ethanol reaction.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Anxiety; Behavi | 2012 |
Involvement of brain ethanol metabolism on acute tolerance development and on ethanol consumption in alcohol-drinker (UChB) and non-drinker (UChA) rats.
Topics: Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Brain; Catalase; Disulfiram; | 2003 |
Disulfiram as an aid to psychotherapy in the case of an impulsive drinker.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Disulfiram; Humans; Psychotherapy | 1957 |
Ask the doctor. I need to quit drinking, but don't think I can do it on my own. Can I use a drug like Antabuse even though I have heart disease?
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Contraindications; Disulfiram; Heart Diseases; Hu | 2004 |
Alcohol ingestion and topical tacrolimus: a disulfiram-like interaction?
Topics: Administration, Topical; Adult; Alcohol Drinking; Disulfiram; Drug Interactions; Female; Humans; Tac | 2005 |
Effect of natural and synthetic polyamines on ethanol intake in UChB drinker rats.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Animals; Biogenic Polyamines; Cyclohexanes; Disu | 2005 |
[Maintaining abstinence after alcohol detoxification].
Topics: Acamprosate; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Ambulatory Care; Behavior Therapy; Cl | 2006 |
Are disulfiram-like reactions associated with abacavir-containing antiretroviral regimens in clinical practice?
Topics: Adult; Alcohol Drinking; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dideoxynucleosides; | 2007 |
Tolerance to disulfiram induced by chronic alcohol intake in the rat.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Cyan | 2008 |
Antabuse effect with cephalosporins.
Topics: Alcohol Drinking; Cefoperazone; Cephalosporins; Disulfiram; Drug Interactions; Ethanol; Humans | 1980 |
Burning off the antabuse.
Topics: Adult; Alcohol Drinking; Alcoholism; Disulfiram; Humans; Male | 1981 |
Gamma-glutamyltransferase, aspartate aminotransferase and alkaline phosphatase as markers of alcohol consumption in out-patient alcoholics.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Alkaline Phosphatase; Ambulatory Care; Aspartate Aminotra | 1981 |
Disulfiram-like reaction to cefmenoxime.
Topics: Adult; Alcohol Drinking; Cefmenoxime; Cefotaxime; Disulfiram; Humans; Male | 1984 |
Behavioral marital therapy couples groups for male alcoholics and their wives.
Topics: Alcohol Drinking; Alcoholism; Behavior Therapy; Combined Modality Therapy; Communication; Disulfiram | 1984 |
Survival methods in the evaluation of the outcome of alcoholism treatment.
Topics: Alcohol Drinking; Alcoholism; Disulfiram; Humans; Male; Prognosis | 1983 |
Can disulfiram use precipitate urges to drink alcohol?
Topics: Alcohol Drinking; Alcoholism; Disulfiram; Humans | 1983 |
Selective suppression of schedule-induced ethanol drinking by antialcoholic drugs in rats.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Conditioning, Operant; Cyanamide; Disulfiram; Male; R | 1984 |
Variation in alcoholism treatment orientation: differential impact upon specific subpopulations.
Topics: Alcohol Drinking; Alcoholism; Behavior Therapy; Disulfiram; Female; Humans; Male; New York; Outcome | 1982 |
Does consumption of alcohol in the presence of disulfiram cause brain damage?
Topics: Acetaldehyde; Alcohol Drinking; Animals; Brain Diseases; Disulfiram; Ethanol; Male; Nerve Degenerati | 1983 |
Control of a secondary pathway of ethanol metabolism by differences in redox state: a story of the failure to arrest the Krebs cycle for drunkenness.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alcohol Drinking; Alcohol Oxidoreductases; Alcoholism | 1981 |
Alcoholism treatment by disulfiram and community reinforcement therapy.
Topics: Adult; Alcohol Drinking; Alcoholism; Ambulatory Care; Behavior Therapy; Community Mental Health Serv | 1982 |
[Antabuse effect during the administration of a topical drug based on monosulfiram].
Topics: Administration, Topical; Adult; Alcohol Drinking; Disulfiram; Humans; Male | 1982 |
Daidzin suppresses ethanol consumption by Syrian golden hamsters without blocking acetaldehyde metabolism.
Topics: Acetaldehyde; Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Behavior, Anima | 1995 |
[Ethanol ingestion following Antabus overdose: acetaldehyde-induced cardiological emergency].
Topics: Acetaldehyde; Adult; Alcohol Drinking; Chest Pain; Chromatography, High Pressure Liquid; Coronary Di | 1995 |
Therapeutic lessons from traditional Oriental medicine to contemporary Occidental pharmacology.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Drinking; Animals; Choice Behavior; Cricetinae; Disulfi | 1994 |
[Metronidazole, alcohol and rosacea].
Topics: Administration, Topical; Alcohol Drinking; Disulfiram; Drug Synergism; Ethanol; Humans; Metronidazol | 1993 |
The efficacy of treatments in reducing alcohol consumption: a meta-analysis.
Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Disulfiram; Humans; Randomized Controlled Trials a | 1996 |
Genetic differences in alcohol drinking preference between inbred strains of mice.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Alcohol Deterrents; Alcohol Drinking; Amitrole; Animals; Brain; | 1997 |
Ambulatory management in alcoholism.
Topics: Alcohol Drinking; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; Antidepressive Agents; Benzodiaz | 1977 |
Psychological medicine. Treatment of alcoholism.
Topics: Adolescent; Adult; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholics Anonymous; Alcoholism; | 1975 |
Use of a pocket-size breath analyzer in the detection and treatment of alcohol misuse.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Ambulatory Care; Breath Tests; Disulfiram; Eth | 1979 |
Spontaneous regression of breast cancer.
Topics: Adult; Alcohol Drinking; Breast Neoplasms; Disulfiram; Female; Goiter; Humans; Malaria; Male; Middle | 1977 |
Maintaining disulfiram ingestion among outpatient alcoholics: a security-deposit contingency contracting procedure.
Topics: Adult; Alcohol Drinking; Alcoholism; Ambulatory Care; Conditioning, Operant; Disulfiram; Evaluation | 1976 |
Suppression of ethanol intake following administration of dopamine-beta-hydroxylase inhibitors in rats.
Topics: Acetaldehyde; Alcohol Drinking; Amines; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfid | 1976 |
Superego factors in alcoholics.
Topics: Alcohol Drinking; Alcoholics Anonymous; Alcoholism; Antisocial Personality Disorder; Disulfiram; Ego | 1975 |
Reversibility of alcohol-induced immune depression.
Topics: Adult; Alcohol Drinking; Alcoholism; Ambulatory Care; Disulfiram; Humans; Immune Tolerance; Immunity | 1992 |
Long-term use of aversive drugs in outpatient alcoholism treatment.
Topics: Adult; Alcohol Drinking; Alcoholism; Ambulatory Care; Aversive Therapy; Disulfiram; Female; Follow-U | 1991 |
[Disulfiram-like effect of cefonicid: first observation].
Topics: Aged; Alcohol Drinking; Cefonicid; Disulfiram; Drug Interactions; Ethanol; Humans; Male | 1990 |
Giving ethanol to alcoholics in a research setting: its effect on compliance with disulfiram treatment.
Topics: Adult; Alcohol Drinking; Alcoholism; Disulfiram; Follow-Up Studies; Humans; Male; Middle Aged; Patie | 1990 |
Alcoholics' attitudes toward and experiences with disulfiram.
Topics: Adult; Alcohol Drinking; Alcoholism; Attitude to Health; Disulfiram; Follow-Up Studies; Humans; Male | 1990 |
Are special treatment facilities for female alcoholics needed? A controlled 2-year follow-up study from a specialized female unit (EWA) versus a mixed male/female treatment facility.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Alcoholism; Combined Modality Therapy; Disulfiram; Female | 1989 |
Medical management of the depressed alcoholic patient.
Topics: Alcohol Drinking; Alcoholism; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Arousal; Depre | 1987 |
Disulfiram reaction during sexual intercourse.
Topics: Adult; Alcohol Drinking; Disulfiram; Drug Interactions; Female; Humans; Sexual Dysfunction, Physiolo | 1988 |
Inpatient treatment of alcoholism: a behavioral approach.
Topics: Alcohol Drinking; Alcoholism; Aversive Therapy; Behavior Therapy; Disulfiram; Female; Humans; Male; | 1987 |
Behavioral use of disulfiram in the treatment of problem drinking.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Behavior Therapy; Combined Modality Therapy; Disulfiram; | 1987 |
Management of alcoholism.
Topics: Alcohol Drinking; Alcoholics Anonymous; Alcoholism; Counseling; Disulfiram; Humans | 1986 |
Antabuse contracts for married alcoholics and their spouses: a method to maintain antabuse ingestion and decrease conflict about drinking.
Topics: Adaptation, Psychological; Adult; Alcohol Drinking; Alcoholism; Behavior Therapy; Combined Modality | 1986 |
Effects of diets decreasing ethanol consumption on acetaldehyde metabolism in UChA and UChB rats.
Topics: Acetaldehyde; Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Brain; Disulfiram; Ethanol; Female; | 1985 |
Liver cytosolic aldehyde dehydrogenases from "alcohol-drinking" and "alcohol-avoiding" mouse strains: purification and molecular properties.
Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Animals; Cytosol; Disulfiram; Histocytochemistry; Hydrogen | 1986 |
Disulfiram hepatotoxicity: case report.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Chemical and Drug Induced Liver Injury; Disulfiram; Drug | 1985 |
A one-year follow-up of men alcoholics given disulfiram.
Topics: Alcohol Drinking; Alcoholism; Disulfiram; Follow-Up Studies; Hospitalization; Humans; Male; Middle A | 1985 |
Alcoholism treatment as an alternative to psychiatric hospitalization.
Topics: Alcohol Drinking; Alcoholics Anonymous; Alcoholism; Combined Modality Therapy; Counseling; Disulfira | 1985 |
Behavioral approaches for problems with alcohol.
Topics: Alcohol Drinking; Alcoholism; Antipsychotic Agents; Aversive Therapy; Behavior Therapy; Disulfiram; | 1974 |
Isolation and characterization of human liver aldehyde dehydrogenase.
Topics: Acetaldehyde; Alcohol Drinking; Aldehydes; Chloral Hydrate; Chloromercuribenzoates; Chromatography, | 1968 |
[Psychopharmacologic drugs in the treatment of alcoholics].
Topics: Alcohol Drinking; Alcoholism; Anticonvulsants; Disulfiram; Humans; Psychoses, Alcoholic; Tranquilizi | 1974 |
Alcoholism among methadone patients: a specific treatment method.
Topics: Alcohol Drinking; Alcoholism; Disulfiram; Heroin; Heroin Dependence; Hospitalization; Humans; Methad | 1973 |
Dreams as a prognostic factor in alcoholism.
Topics: Adult; Age Factors; Alcohol Drinking; Alcoholism; Ambulatory Care; Disulfiram; Dreams; Educational S | 1973 |
A residential alcoholism treatment program for American Indians.
Topics: Adolescent; Adult; Alcohol Drinking; Alcoholism; California; Disulfiram; Female; Group Processes; He | 1973 |
[Treatment of chronic alcoholism and other addictions].
Topics: Alcohol Drinking; Alcoholism; Behavior Therapy; Combined Modality Therapy; Disulfiram; Hospitalizati | 1966 |
[Effect of withdrawal therapy on urinary excretion of 17-ketosteroids in male patients with chronic alcoholism].
Topics: 17-Ketosteroids; Adult; Alcohol Drinking; Alcoholism; Chronic Disease; Disulfiram; Humans; Insulin; | 1972 |
Controlled drinking for alcoholism.
Topics: Alcohol Drinking; Alcoholism; Depression; Disulfiram; Humans; Recurrence | 1972 |
How to help the chronic alcoholic.
Topics: Alcohol Drinking; Alcoholism; Antidepressive Agents; Chronic Disease; Disulfiram; Humans; Metronidaz | 1972 |
Helping alcoholics abstain: an implantable substance.
Topics: Alcohol Drinking; Alcoholism; Cannabis; Delayed-Action Preparations; Disulfiram; Heroin; Humans; Met | 1972 |
On and off the wagon. Reasons for drinking and abstaining by alcoholics.
Topics: Adult; Alcohol Drinking; Alcoholism; Attitude to Health; Disulfiram; Ethanol; Follow-Up Studies; Hos | 1972 |
Three alcohol programs for American Indians.
Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Alcoholism; Culture; Disulfiram; Female; Fin | 1972 |
Outpatient treatment of alcoholics. Effects of status, stability and nature of treatment.
Topics: Adult; Age Factors; Alcohol Drinking; Alcoholism; Attitude; Disulfiram; Educational Status; Emotions | 1971 |
Antabuse in a clinic program.
Topics: Alcohol Drinking; Alcoholism; Disulfiram; Humans; Mental Health Services | 1971 |
Difficulties of disulfiram therapy with alcoholics.
Topics: Alcohol Drinking; Alcoholism; Appointments and Schedules; Disulfiram; Hospitals, Psychiatric; Humans | 1971 |
The prognosis of alcohol addicts treated by a specialized unit.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Alcoholism; Disulfiram; Hospitalization; Humans; Male; M | 1968 |
Effects of disulfiram therapy on relationships within the Navaho drinking group.
Topics: Alcohol Drinking; Alcoholism; Culture; Disulfiram; Group Structure; Humans; Indians, North American; | 1968 |
A clinical study of LSD treatment in alcoholism.
Topics: Adult; Alcohol Drinking; Alcoholism; Disulfiram; Ethanol; Follow-Up Studies; Humans; Hypnosis; Lyser | 1969 |