distigmine has been researched along with MELAS Syndrome in 1 studies
distigmine : A carbamate ester resulting from the formal condensation of both carboxy groups of hexane-1,6-diylbis(methylcarbamic acid) with the hydroxy group of 3-hydroxy-1-methylpyridinium.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 34-year-old man with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) showed chronic intestinal pseudo-obstruction (CIPO), which was improved by the administration of distigmine bromide." | 7.74 | [Distigmine bromide improves chronic intestinal pseudo-obstruction in a case of MELAS]. ( Hakii, Y; Kishida, H; Koyano, S; Kuroiwa, Y; Nakae, Y; Suzuki, Y, 2007) |
| "A 34-year-old man with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) showed chronic intestinal pseudo-obstruction (CIPO), which was improved by the administration of distigmine bromide." | 3.74 | [Distigmine bromide improves chronic intestinal pseudo-obstruction in a case of MELAS]. ( Hakii, Y; Kishida, H; Koyano, S; Kuroiwa, Y; Nakae, Y; Suzuki, Y, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakae, Y | 1 |
| Kishida, H | 1 |
| Hakii, Y | 1 |
| Koyano, S | 1 |
| Suzuki, Y | 1 |
| Kuroiwa, Y | 1 |
1 other study available for distigmine and MELAS Syndrome
| Article | Year |
|---|---|
[Distigmine bromide improves chronic intestinal pseudo-obstruction in a case of MELAS].
Topics: Adult; Chronic Disease; Humans; Intestinal Pseudo-Obstruction; Male; MELAS Syndrome; Pyridinium Comp | 2007 |