disopyramide has been researched along with Ventricular Fibrillation in 67 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral disopyramide given prophylactically following myocardial infarction has been compared with placebo in a double-blind trial using continuous-tape monoriting of the electocardiogram." | 9.04 | Oral disopyramide in prophylaxis of arrhythmias following myocardial infarction. ( Besterman, EM; Jennings, G; Jones, MS; Kidner, PH; Model, DG; Turner, PP, 1976) |
| "Patients with acute myocardial infarction admitted to open wards of three hospitals were given either oral disopyramide (100 mg four times daily) or matching placebo, prophylactically, for seven days." | 9.04 | Oral disopyramide for the prevention of arrhythmias in patients with acute myocardial infarction admitted to open wards. ( Besterman, EM; Carmichael, DJ; Gillham, AD; Griffiths, JW; Kidner, PH; Summers, GD; Zainal, N, 1977) |
| "Intraindividual comparison of the acute response to intravenous quinidine and to intravenous disopyramide was performed in 27 patients with sustained ventricular tachycardia (VT) who underwent serial electrophysiological studies." | 7.67 | Effects of intravenous disopyramide and quinidine on normal myocardium and on the characteristics of arrhythmias: intraindividual comparison in patients with sustained ventricular tachycardia. ( Brachmann, J; Kübler, W; Lengfelder, W; Rizos, I; Schmitt, C; Senges, J; von Olshausen, K, 1987) |
| "The effect of disopyramide phosphate (DP) infusion (1 mg/Kg and 2 mg/Kg BW) on ventricular fibrillation threshold (VFT) was studied in anesthetized dogs." | 7.66 | The effect of disopyramide phosphate on ventricular fibrillation threshold of normal and ischemic ventricles. ( Dohi, Y; Tajima, T, 1983) |
| "The efficacy of disopyramide in the management of sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) was evaluated in 50 patients by programmed ventricular stimulation: 38 patients had coronary artery disease (16 with left ventricular aneurysm), 8 had other cardiac diseases, and 4 had no apparent heart disease." | 7.66 | Disopyramide: evaluation of electrophysiologic effects and clinical efficacy in patients with sustained ventricular tachycardia or ventricular fibrillation. ( Buxton, AE; Josephson, ME; Lerman, BB; Waxman, HL, 1983) |
| "The effects of intravenous doses of Org 6001 and disopyramide (10 mg/kg) known to confer protection against early postligation-induced arrhythmias in the anaesthetized rat when given prophylactically, were assessed following postligation administration." | 7.66 | The effects of postligation administration of ORG 6001 and disopyramide on early ischaemia-induced arrhythmias in the anaesthetized rat. ( Marshall, RJ; Muir, AW; Winslow, E, 1982) |
| "Two patients with atrial arrhythmias are described who developed ventricular tachyarrhythmias shortly after starting disopyramide therapy." | 7.66 | Ventricular tachyarrhythmias induced by disopyramide and other similar anti-arrhythmic drugs. ( Croft, CH; Kennelly, BM, 1981) |
| "This study was performed to investigate the prophylactic effect of disopyramide phosphate on ventricular fibrillation in acute myocardial infarction." | 7.66 | Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine. ( Fukuzaki, H; Hatani, M; Hori, Y; Imai, N; Nadai, T; Okamoto, R; Takano, S; Toh, H, 1981) |
| "Three cases are described with documented ventricular fibrillation shortly after the patients received disopyramide in moderate dosage." | 7.66 | Disopyramide-induced ventricular fibrillation. ( Gracey, JG; Knoch, HR; Martin, CE; Nicholson, WJ, 1979) |
| "Since its approval by the FDA six years ago, oral disopyramide has earned a recognized role in the treatment of ventricular arrhythmias." | 6.15 | Disopyramide: six years' experience. ( Wallace, AG; Wilson, RR, 1983) |
| "Oral disopyramide given prophylactically following myocardial infarction has been compared with placebo in a double-blind trial using continuous-tape monoriting of the electocardiogram." | 5.04 | Oral disopyramide in prophylaxis of arrhythmias following myocardial infarction. ( Besterman, EM; Jennings, G; Jones, MS; Kidner, PH; Model, DG; Turner, PP, 1976) |
| "Patients with acute myocardial infarction admitted to open wards of three hospitals were given either oral disopyramide (100 mg four times daily) or matching placebo, prophylactically, for seven days." | 5.04 | Oral disopyramide for the prevention of arrhythmias in patients with acute myocardial infarction admitted to open wards. ( Besterman, EM; Carmichael, DJ; Gillham, AD; Griffiths, JW; Kidner, PH; Summers, GD; Zainal, N, 1977) |
| "Since disopyramide was introduced 5 years ago, the therapeutic spectrum of this drug in treating patients with ventricular and atrial arrhythmias has been found to be similar to that of the other type I antiarrhythmic drugs, quinidine and procainamide." | 4.76 | Disopyramide. ( Desai, J; Morady, F; Scheinman, MM, 1982) |
| " Twenty-six of these patients, who had ventricular fibrillation during single-drug therapy with quinidine, procainamide, or disopyramide, were compared with a control group of 62 patients who had been treated similarly for ventricular arrhythmias but did not have ventricular fibrillation during treatment." | 3.67 | Clinical characteristics of patients with ventricular fibrillation during antiarrhythmic drug therapy. ( Heger, JJ; Miles, WM; Minardo, JD; Prystowsky, EN; Zipes, DP, 1988) |
| "Intraindividual comparison of the acute response to intravenous quinidine and to intravenous disopyramide was performed in 27 patients with sustained ventricular tachycardia (VT) who underwent serial electrophysiological studies." | 3.67 | Effects of intravenous disopyramide and quinidine on normal myocardium and on the characteristics of arrhythmias: intraindividual comparison in patients with sustained ventricular tachycardia. ( Brachmann, J; Kübler, W; Lengfelder, W; Rizos, I; Schmitt, C; Senges, J; von Olshausen, K, 1987) |
| "The effect of disopyramide phosphate (DP) infusion (1 mg/Kg and 2 mg/Kg BW) on ventricular fibrillation threshold (VFT) was studied in anesthetized dogs." | 3.66 | The effect of disopyramide phosphate on ventricular fibrillation threshold of normal and ischemic ventricles. ( Dohi, Y; Tajima, T, 1983) |
| "The efficacy of disopyramide in the management of sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) was evaluated in 50 patients by programmed ventricular stimulation: 38 patients had coronary artery disease (16 with left ventricular aneurysm), 8 had other cardiac diseases, and 4 had no apparent heart disease." | 3.66 | Disopyramide: evaluation of electrophysiologic effects and clinical efficacy in patients with sustained ventricular tachycardia or ventricular fibrillation. ( Buxton, AE; Josephson, ME; Lerman, BB; Waxman, HL, 1983) |
| "The effects of intravenous doses of Org 6001 and disopyramide (10 mg/kg) known to confer protection against early postligation-induced arrhythmias in the anaesthetized rat when given prophylactically, were assessed following postligation administration." | 3.66 | The effects of postligation administration of ORG 6001 and disopyramide on early ischaemia-induced arrhythmias in the anaesthetized rat. ( Marshall, RJ; Muir, AW; Winslow, E, 1982) |
| "Two patients with atrial arrhythmias are described who developed ventricular tachyarrhythmias shortly after starting disopyramide therapy." | 3.66 | Ventricular tachyarrhythmias induced by disopyramide and other similar anti-arrhythmic drugs. ( Croft, CH; Kennelly, BM, 1981) |
| "This study was performed to investigate the prophylactic effect of disopyramide phosphate on ventricular fibrillation in acute myocardial infarction." | 3.66 | Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine. ( Fukuzaki, H; Hatani, M; Hori, Y; Imai, N; Nadai, T; Okamoto, R; Takano, S; Toh, H, 1981) |
| "Three cases are described with documented ventricular fibrillation shortly after the patients received disopyramide in moderate dosage." | 3.66 | Disopyramide-induced ventricular fibrillation. ( Gracey, JG; Knoch, HR; Martin, CE; Nicholson, WJ, 1979) |
| "Brugada syndrome is characterized by an ST segment elevation in leads V1-V3 and a high incidence of ventricular fibrillation (VF)." | 2.69 | Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. ( Aihara, N; Antzelevitch, C; Kamakura, S; Kurita, T; Shimizu, W; Sunagawa, K; Suyama, K; Taguchi, A; Takaki, H, 2000) |
| "A 67-year-old man who had cardiopulmonary arrest (CPA) at home was admitted to our institution." | 1.42 | Early-Morning Type Ventricular Fibrillation With J Wave. ( Fujino, T; Ikeda, T; Tsubota, T; Yamazaki, Y, 2015) |
| "When examined on premature beats, AT was delayed, depending on the coupling interval and the fiber direction when saline, flecainide or lidocaine was infused." | 1.30 | Electrophysiologic effects of sodium channel blockade on anisotropic conduction and conduction block in canine myocardium: preferential slowing of longitudinal conduction by flecainide versus disopyramide or lidocaine. ( Kondo, T; Kubota, I; Tachibana, H; Tomoike, H; Yamaki, M, 1997) |
| "Mexiletine tended to increase DFT [from 4." | 1.29 | Prolongation of intraventricular conduction time associated with fatal [correction of fetal] impairment of defibrillation efficiency during treatment with class I antiarrhythmic agents. ( Ajiki, K; Inoue, H; Kuo, TT; Murakawa, Y; Nakajima, T; Oikawa, N; Sezaki, K; Sugimoto, T; Usui, M; Yamashita, T, 1995) |
| "Ventricular fibrillation was induced by endocardial electrical stimulation in pigs anaesthetised with pentobarbitone sodium (30 mg/kg intravenously)." | 1.29 | Effects of blockade of fast and slow inward current channels on ventricular fibrillation in the pig heart. ( Adgey, AA; Allen, JD; Devine, AB; Stewart, AJ, 1996) |
| " The latter, however, was taking antiarrhythmic drugs at a dosage less than that proved to be effective during electropharmacological testing." | 1.27 | [Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation]. ( Delise, P; Di Pede, F; Piccolo, E; Raviele, A, 1984) |
| "Mexiletine was combined with a conventional type IA antiarrhythmic agent in 25 patients (49%)." | 1.27 | Intolerance and ineffectiveness of mexiletine in patients with serious ventricular arrhythmias. ( Bardy, GH; Fahrenbruch, CE; Graham, EL; Greene, HL; Poole, JE; Pulaski, WP; Werner, JA, 1986) |
| "Amiodarone was without effect." | 1.26 | Comparative antidysrhythmic profiles of bepridil, amiodarone and disopyramide in the guinea-pig and dog. ( Basiez, M; Beaughard, M; Duchene-Marullaz, P; Labrid, C; Leinot, M, 1981) |
| "Disopyramide has the advantage of being available both as an oral and an intravenous preparation and is a useful drug to be added to the list of more conventional anti-dysrhythmic agents." | 1.26 | Disopyramide--an effective treatment for lignocaine resistant ventricular dysrhythmias. ( Green, AG, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (70.15) | 18.7374 |
| 1990's | 12 (17.91) | 18.2507 |
| 2000's | 5 (7.46) | 29.6817 |
| 2010's | 2 (2.99) | 24.3611 |
| 2020's | 1 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Ruenitz, PC | 1 |
| Mokler, CM | 1 |
| Vlok, N | 1 |
| Hedding, KA | 1 |
| Van Dyk, MA | 1 |
| Fujino, T | 1 |
| Yamazaki, Y | 1 |
| Tsubota, T | 1 |
| Ikeda, T | 1 |
| Sumi, S | 1 |
| Maruyama, S | 1 |
| Shiga, Y | 1 |
| Kodama, S | 1 |
| Miyoshi, K | 1 |
| Tojou, H | 1 |
| Yamanouchi, Y | 1 |
| Urata, H | 1 |
| Sugao, M | 1 |
| Fujiki, A | 1 |
| Nishida, K | 1 |
| Sakabe, M | 1 |
| Tsuneda, T | 1 |
| Iwamoto, J | 1 |
| Mizumaki, K | 1 |
| Inoue, H | 2 |
| Lüderitz, B | 1 |
| Manz, M | 1 |
| Steinbeck, G | 1 |
| Wilson, RR | 1 |
| Wallace, AG | 1 |
| Tajima, T | 1 |
| Dohi, Y | 1 |
| Allen-Narker, RA | 1 |
| Roberts, CJ | 1 |
| Marshall, AJ | 1 |
| Jordan, SC | 1 |
| Barritt, DW | 1 |
| Goodfellow, RM | 1 |
| Raviele, A | 1 |
| Di Pede, F | 1 |
| Delise, P | 1 |
| Piccolo, E | 1 |
| Bergey, JL | 1 |
| Sulkowski, T | 1 |
| Much, DR | 1 |
| Wendt, RL | 1 |
| Lerman, BB | 1 |
| Waxman, HL | 1 |
| Buxton, AE | 1 |
| Josephson, ME | 1 |
| Labrid, C | 1 |
| Leinot, M | 1 |
| Beaughard, M | 1 |
| Basiez, M | 1 |
| Duchene-Marullaz, P | 1 |
| Silberschmidt, U | 1 |
| Breithardt, G | 2 |
| Seipel, L | 2 |
| Abendroth, RR | 1 |
| Loogen, F | 1 |
| Morady, F | 1 |
| Scheinman, MM | 1 |
| Desai, J | 1 |
| Marshall, RJ | 2 |
| Muir, AW | 2 |
| Winslow, E | 2 |
| Ko, PT | 1 |
| Gulamhusein, S | 1 |
| Kostuk, WJ | 1 |
| Klein, GJ | 1 |
| Croft, CH | 1 |
| Kennelly, BM | 1 |
| Hori, Y | 1 |
| Okamoto, R | 1 |
| Hatani, M | 1 |
| Imai, N | 1 |
| Toh, H | 1 |
| Takano, S | 1 |
| Nadai, T | 1 |
| Fukuzaki, H | 1 |
| Edhag, O | 1 |
| Forssell, G | 1 |
| Schenck-Gustafsson, K | 1 |
| Rothman, MT | 1 |
| Warrington, SJ | 1 |
| Hamer, J | 1 |
| Haerten, K | 1 |
| Crijns, HJ | 1 |
| Wiesfeld, AC | 1 |
| Posma, JL | 1 |
| Lie, KI | 1 |
| Komori, S | 2 |
| Sano, S | 1 |
| Li, BH | 1 |
| Matsumura, K | 1 |
| Naitoh, A | 1 |
| Mochizuki, S | 1 |
| Ishihara, T | 1 |
| Watanabe, A | 1 |
| Umetani, K | 1 |
| Ijiri, H | 1 |
| Murakawa, Y | 2 |
| Kuo, TT | 1 |
| Sezaki, K | 1 |
| Nakajima, T | 1 |
| Usui, M | 1 |
| Yamashita, T | 1 |
| Ajiki, K | 1 |
| Oikawa, N | 1 |
| Sugimoto, T | 2 |
| Sawanobori, T | 1 |
| Tamura, K | 1 |
| Kane, KA | 1 |
| Parratt, JR | 1 |
| Miyanuma, H | 1 |
| Sakurai, M | 1 |
| Odaka, H | 1 |
| Yamazaki, T | 1 |
| Mitobe, H | 1 |
| Muraguti, I | 1 |
| Iwama, N | 1 |
| Stewart, AJ | 1 |
| Allen, JD | 1 |
| Devine, AB | 1 |
| Adgey, AA | 1 |
| Paar, D | 1 |
| Terjung, B | 1 |
| Sauerbruch, T | 1 |
| Aupetit, JF | 1 |
| Loufoua-Moundanga, J | 1 |
| Faucon, G | 1 |
| Timour, Q | 1 |
| Chinushi, M | 1 |
| Aizawa, Y | 1 |
| Ogawa, Y | 1 |
| Shiba, M | 1 |
| Takahashi, K | 1 |
| Kondo, T | 1 |
| Yamaki, M | 3 |
| Kubota, I | 3 |
| Tachibana, H | 3 |
| Tomoike, H | 3 |
| Watanabe, T | 2 |
| Yamauchi, S | 2 |
| Ruskin, JN | 1 |
| Shimizu, W | 3 |
| Matsuo, K | 1 |
| Takagi, M | 2 |
| Tanabe, Y | 1 |
| Aiba, T | 1 |
| Taguchi, A | 3 |
| Suyama, K | 3 |
| Kurita, T | 3 |
| Aihara, N | 3 |
| Kamakura, S | 3 |
| Takaki, H | 2 |
| Antzelevitch, C | 1 |
| Sunagawa, K | 1 |
| Spurrell, RA | 1 |
| Thorburn, CW | 1 |
| Camm, J | 1 |
| Sowton, E | 1 |
| Deuchar, DC | 1 |
| Jennings, G | 1 |
| Jones, MS | 1 |
| Besterman, EM | 2 |
| Model, DG | 1 |
| Turner, PP | 1 |
| Kidner, PH | 3 |
| Perroni, GB | 1 |
| Briguglio, FS | 1 |
| Oddo, A | 1 |
| Trovato, G | 1 |
| Zainal, N | 1 |
| Carmichael, DJ | 1 |
| Griffiths, JW | 1 |
| Gillham, AD | 1 |
| Summers, GD | 1 |
| Green, AG | 1 |
| Koch-Weser, J | 1 |
| Nicholson, WJ | 1 |
| Martin, CE | 1 |
| Gracey, JG | 1 |
| Knoch, HR | 1 |
| Forester, D | 1 |
| Frieden, J | 1 |
| de Lanerolle, TD | 2 |
| Harner, RH | 1 |
| Boyd, RB | 1 |
| Edmunds, V | 1 |
| Wilcox, AH | 1 |
| Atukorale, DP | 1 |
| Kim, SG | 1 |
| Seiden, SW | 1 |
| Matos, JA | 1 |
| Waspe, LE | 1 |
| Fisher, JD | 1 |
| Somberg, JC | 1 |
| Miura, D | 1 |
| Keefe, DL | 1 |
| Toda, I | 1 |
| Nozaki, A | 1 |
| Kawakubo, K | 1 |
| Ellsworth, AJ | 1 |
| Horn, JR | 1 |
| Raisys, VA | 1 |
| Miyagawa, LA | 1 |
| Bell, JL | 1 |
| Minardo, JD | 1 |
| Heger, JJ | 1 |
| Miles, WM | 1 |
| Zipes, DP | 1 |
| Prystowsky, EN | 1 |
| Wyse, DG | 1 |
| Mitchell, LB | 1 |
| Duff, HJ | 1 |
| Rizos, I | 1 |
| Brachmann, J | 1 |
| Lengfelder, W | 1 |
| Schmitt, C | 1 |
| von Olshausen, K | 1 |
| Kübler, W | 1 |
| Senges, J | 1 |
| Poole, JE | 1 |
| Werner, JA | 1 |
| Bardy, GH | 1 |
| Graham, EL | 1 |
| Pulaski, WP | 1 |
| Fahrenbruch, CE | 1 |
| Greene, HL | 1 |
| Belhassen, B | 1 |
| Shapira, I | 1 |
| Shoshani, D | 1 |
| Paredes, A | 1 |
| Miller, H | 1 |
| Laniado, S | 1 |
| Yen, CH | 1 |
| Lowrie, HS | 1 |
| Dean, RR | 1 |
| Casagrande, C | 1 |
| Galli, A | 1 |
| Ferrini, R | 1 |
| Miragoli, G | 1 |
| Ferrari, G | 1 |
5 reviews available for disopyramide and Ventricular Fibrillation
| Article | Year |
|---|---|
Disopyramide: six years' experience.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Humans; Parasympa | 1983 |
[Disopyramide poisoning].
Topics: Acid-Base Equilibrium; Arrhythmias, Cardiac; Disopyramide; Heart Ventricles; Hemoperfusion; Humans; | 1981 |
Disopyramide.
Topics: Arrhythmias, Cardiac; Disopyramide; Drug Interactions; Electrophysiology; Heart; Heart Block; Humans | 1982 |
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, | 1978 |
The treatment of ventricular rhythm disturbances.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premat | 1986 |
9 trials available for disopyramide and Ventricular Fibrillation
| Article | Year |
|---|---|
Disopyramide: six years' experience.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Humans; Parasympa | 1983 |
Prophylaxis against ventricular arrhythmias in suspected acute myocardial infarction: a comparison of tocainide and disopyramide.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Female; Humans; Lidocaine; Male; Middle | 1984 |
Serial electrophysiological testing of antiarrhythmic drug efficacy in patients with recurrent ventricular tachycardia.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Coronary | 1980 |
Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Disopyramide; Electrocardiography; Flecain | 2000 |
Oral disopyramide in prophylaxis of arrhythmias following myocardial infarction.
Topics: Administration, Oral; Arrhythmias, Cardiac; Atrial Fibrillation; Clinical Trials as Topic; Disopyram | 1976 |
Oral disopyramide for the prevention of arrhythmias in patients with acute myocardial infarction admitted to open wards.
Topics: Acute Disease; Administration, Oral; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyram | 1977 |
Anti-dysrhythmic treatment in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind | 1979 |
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, | 1978 |
Discordance between ambulatory monitoring and programmed stimulation in assessing efficacy of class IA antiarrhythmic agents in patients with ventricular tachycardia.
Topics: Aged; Ambulatory Care; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artific | 1985 |
55 other studies available for disopyramide and Ventricular Fibrillation
| Article | Year |
|---|---|
Antiarrhythmic activity of some N-alkylbispidinebenzamides.
Topics: Animals; Anti-Arrhythmia Agents; Benzamides; Disopyramide; Female; Heart Rate; In Vitro Techniques; | 1979 |
Saved by the pump: Two successful resuscitations utilising emergency department-initiated extracorporeal cardiopulmonary resuscitation in South Africa.
Topics: Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Cardiotoxicity; Disopyramide; Extracorporeal | 2021 |
Early-Morning Type Ventricular Fibrillation With J Wave.
Topics: Aged; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Defibrillators, Implantable; Disopyrami | 2015 |
High efficacy of disopyramide in the management of ventricular fibrillation storms in a patient with Brugada syndrome.
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillators, Implantable; Disopyramide; Electrocardiogr | 2010 |
Repolarization dynamics in patients with idiopathic ventricular fibrillation: pharmacological therapy with bepridil and disopyramide.
Topics: Adult; Bepridil; Disopyramide; Drug Therapy, Combination; Heart Rate; Humans; Male; Middle Aged; Ven | 2005 |
[Sudden heart death in ventricular heart rhythm disorders: possibilities and limits of long-term therapy].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden; Disopyramide; German | 1984 |
The effect of disopyramide phosphate on ventricular fibrillation threshold of normal and ischemic ventricles.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Disease; Disopyramide; Dogs; Electric Stim | 1983 |
[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation].
Topics: Adult; Aged; Amiodarone; Death, Sudden; Disopyramide; Drug Therapy, Combination; Electrocardiography | 1984 |
Antiarrhythmic, hemodynamic and cardiac electrophysiological evaluation of N-(2,6-dimethylphenyl)-N'-[3-(1-methylethylamino)propyl]urea (Wy-42,362).
Topics: Aconitine; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Coronary Vessels; Disopyramide; Dogs | 1983 |
Disopyramide: evaluation of electrophysiologic effects and clinical efficacy in patients with sustained ventricular tachycardia or ventricular fibrillation.
Topics: Adult; Aged; Cardiac Pacing, Artificial; Disopyramide; Electrocardiography; Female; Heart Ventricles | 1983 |
Comparative antidysrhythmic profiles of bepridil, amiodarone and disopyramide in the guinea-pig and dog.
Topics: Aconitine; Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Bepridil; Disopyramide; Dogs; F | 1981 |
The effects of postligation administration of ORG 6001 and disopyramide on early ischaemia-induced arrhythmias in the anaesthetized rat.
Topics: Androstanols; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cor | 1982 |
Torsades de pointes, a common arrhythmia, induced by medication.
Topics: Aged; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Female; Humans; Male; Middle Aged; | 1982 |
Ventricular tachyarrhythmias induced by disopyramide and other similar anti-arrhythmic drugs.
Topics: Aged; Disopyramide; Electrocardiography; Female; Follow-Up Studies; Heart Ventricles; Humans; Male; | 1981 |
Development of a severe model of early coronary artery ligation-induced dysrhythmias in the anaesthetized rat.
Topics: Androstanols; Angiotensin II; Animals; Arrhythmias, Cardiac; Atropine; Catecholamines; Coronary Vess | 1981 |
Studies on the preventive method of lowered ventricular fibrillation threshold during experimental acute myocardial infarctions. A comparison between disopyramide phosphate and lidocaine.
Topics: Animals; Disease Models, Animal; Disopyramide; Dogs; Dose-Response Relationship, Drug; Injections, I | 1981 |
[Ventricular fibrillation during disopyramide treatment].
Topics: Aged; Disopyramide; Electrocardiography; Female; Humans; Male; Middle Aged; Pyridines; Tachycardia; | 1981 |
Prolonged QT interval, atrioventricular block, and torsade de pointes after antiarrhythmic therapy.
Topics: Aged; Disopyramide; Electrocardiography; Female; Heart; Heart Block; Humans; Lidocaine; Pyridines; T | 1980 |
Some cardiovascular problems with disopyramide.
Topics: Adult; Aged; Arrhythmia, Sinus; Bundle-Branch Block; Cardiovascular Diseases; Disopyramide; Female; | 1980 |
[Paradoxic response to disopyramide and quinidine (author's transl)].
Topics: Adult; Aged; Disopyramide; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Mitral Valve; Py | 1980 |
Favourable outcome in idiopathic ventricular fibrillation with treatment aimed at prevention of high sympathetic tone and suppression of inducible arrhythmias.
Topics: Adult; Anti-Arrhythmia Agents; Clinical Protocols; Combined Modality Therapy; Defibrillators, Implan | 1995 |
Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Complexes, Premature; Coronary Disease; Dis | 1995 |
Prolongation of intraventricular conduction time associated with fatal [correction of fetal] impairment of defibrillation efficiency during treatment with class I antiarrhythmic agents.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Defibrillators, Implantable; Disopyramide; Do | 1995 |
Effects of NS-2, a new class 1 antiarrhythmic agent, and AFD-19, its active metabolite, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats: comparison with disopyramide and mexiletine.
Topics: Amino Alcohols; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Coronary Dise | 1994 |
[Two cases of idiopathic ventricular fibrillation with interesting electrocardiographic findings].
Topics: Adult; Death, Sudden, Cardiac; Disopyramide; Electric Stimulation; Electrocardiography; Humans; Male | 1993 |
Effects of blockade of fast and slow inward current channels on ventricular fibrillation in the pig heart.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Flecai | 1996 |
Life-threatening interaction between clarithromycin and disopyramide.
Topics: Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Disopyramide | 1997 |
Ischaemia-induced loss or reversal of the effects of the class I antiarrhythmic drugs on vulnerability to fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Vessels; Disopyramide; Electric Stimulatio | 1997 |
Discrepant drug action of disopyramide on ECG abnormalities and induction of ventricular arrhythmias in a patient with Brugada syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Dose-Response Relationship, | 1997 |
Electrophysiologic effects of sodium channel blockade on anisotropic conduction and conduction block in canine myocardium: preferential slowing of longitudinal conduction by flecainide versus disopyramide or lidocaine.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Dogs; Electric Conducti | 1997 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyrami | 1999 |
Idiopathic ventricular fibrillation: is there a role for electrophysiologic-guided antiarrhythmic drug therapy?
Topics: Anti-Arrhythmia Agents; Disopyramide; Echocardiography; Humans; Procainamide; Quinidine; Ventricular | 1999 |
Body surface distribution and response to drugs of ST segment elevation in Brugada syndrome: clinical implication of eighty-seven-lead body surface potential mapping and its application to twelve-lead electrocardiograms.
Topics: Action Potentials; Adolescent; Adrenergic beta-Agonists; Adult; Aged; Anti-Arrhythmia Agents; Body S | 2000 |
Clinical characteristics of patients with spontaneous or inducible ventricular fibrillation without apparent heart disease presenting with J wave and ST segment elevation in inferior leads.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Defibrillators, Implantable; Disopyrami | 2000 |
Anisotropic effects of sodium channel blockers on the wavelength for ventricular excitation in dogs.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Dogs; Electr | 2000 |
Effects of disopyramide on electrophysiological properties of specialized conduction system in man and on accessory atrioventricular pathway in Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adult; Atrial Fibrillation; Atrioventricular Node; Cardiac Complexes, Premature; Child; | 1975 |
[Data on disopyridamide therapy of some arrhythmias].
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Disopyramid | 1977 |
Disopyramide--an effective treatment for lignocaine resistant ventricular dysrhythmias.
Topics: Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Female; Humans; Lidocaine; Male; M | 1979 |
Disopyramide-induced ventricular fibrillation.
Topics: Administration, Oral; Aged; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Female; Heart B | 1979 |
Treatment of arrhythmias in the Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Atrial Fibrillation; Disopyramide; Humans; Injections, Intravenous; Lidocaine; | 1979 |
Quinidine effects due to disopyramide.
Topics: Aged; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Female; Heart; Humans; Pyridines; Ven | 1978 |
Disopyramide in ventricular fibrillation.
Topics: Disopyramide; Humans; Pyridines; Ventricular Fibrillation | 1977 |
Resistant ventricular tachycardias and recurrent cardiac arrests. 96 episodes.
Topics: Aged; Disopyramide; Electric Countershock; Heart Aneurysm; Humans; Male; Myocardial Infarction; Prop | 1977 |
Prevention of ventricular arrhythmias after myocardial infarction.
Topics: Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Propranolol; Quini | 1977 |
Disopyramide in a case of recurrent ventricular fibrillation.
Topics: Aged; Disopyramide; Humans; Lidocaine; Male; Pyridines; Recurrence; Ventricular Fibrillation | 1976 |
Disopyramide in ventricular fibrillation.
Topics: Anti-Arrhythmia Agents; Disopyramide; Humans; Male; Middle Aged; Pyridines; Ventricular Fibrillation | 1976 |
Effects of antiarrhythmic drugs on the repetitive extrasystole threshold and the ventricular fibrillation threshold.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Disopyram | 1989 |
Disopyramide and N-monodesalkyl disopyramide in serum and breast milk.
Topics: Adult; Disopyramide; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Hu | 1989 |
Clinical characteristics of patients with ventricular fibrillation during antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Disopyramide; Diuretics; Drug Th | 1988 |
Procainamide, disopyramide and quinidine: discordant antiarrhythmic effects during crossover comparison in patients with inducible ventricular tachycardia.
Topics: Adult; Aged; Disopyramide; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Ma | 1987 |
Effects of intravenous disopyramide and quinidine on normal myocardium and on the characteristics of arrhythmias: intraindividual comparison in patients with sustained ventricular tachycardia.
Topics: Adult; Aged; Aged, 80 and over; Cardiac Pacing, Artificial; Coronary Disease; Disopyramide; Electroc | 1987 |
Intolerance and ineffectiveness of mexiletine in patients with serious ventricular arrhythmias.
Topics: Cardiac Pacing, Artificial; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophy | 1986 |
Idiopathic ventricular fibrillation: inducibility and beneficial effects of class I antiarrhythmic agents.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac Pacing, Artificial; Disopyramide; Dr | 1987 |
Compounds related to 4-disopropylamino-2-phenyl-2(2-pyridyl)butyramide. Their synthesis and antiarrhythmic activity.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Vessels; Disopyramide; Dogs; Heart Rate; Ligation; Ouabain | 1974 |
Synthesis and antiarrhythmic activity of 5,5-disubstituted-3-aminoalkylhydantions and some heterocyclic and noncyclic analogues.
Topics: Alkylation; Amides; Animals; Arrhythmias, Cardiac; Diethylamines; Dimethylamines; Disopyramide; Hete | 1974 |