Page last updated: 2024-10-26

disopyramide and Ventricular Dysfunction, Left

disopyramide has been researched along with Ventricular Dysfunction, Left in 5 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.

Research Excerpts

ExcerptRelevanceReference

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamada, M1
Ikeda, S1
Shigematsu, Y1
Sinclair, RC1
Danjoux, GR1
Kajimoto, K1
Imai, T1
Minami, Y1
Kasanuki, H1
Takada, Y1
Isobe, S1
Okada, M1
Ando, A1
Nonokawa, M1
Inden, Y1
Tomita, Y1
Suzuki, A1
Hirai, M1
Murohara, T1
Sakai, Y1
Hayashi, Y1
Tomobuchi, Y1
Hano, T1
Nishio, I1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy-- a Multicenter Randomized Control Trial[NCT02948998]Phase 4260 participants (Anticipated)Interventional2018-05-14Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for disopyramide and Ventricular Dysfunction, Left

ArticleYear
Advances in medical treatment of hypertrophic cardiomyopathy.
    Journal of cardiology, 2014, Volume: 64, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Calcium Channel Blocke

2014

Trials

1 trial available for disopyramide and Ventricular Dysfunction, Left

ArticleYear
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
    Annals of nuclear medicine, 2004, Volume: 18, Issue:3

    Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart V

2004

Other Studies

3 other studies available for disopyramide and Ventricular Dysfunction, Left

ArticleYear
Cardiopulmonary exercise testing diagnosis of myocardial suppression.
    Anaesthesia, 2009, Volume: 64, Issue:7

    Topics: Aged; Aneurysm; Anti-Arrhythmia Agents; Disopyramide; Exercise Test; Humans; Male; Preoperative Care

2009
Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline.
    The American journal of cardiology, 2010, Nov-01, Volume: 106, Issue:9

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography, D

2010
Dynamic outflow obstruction due to the transient extensive left ventricular wall motion abnormalities caused by acute myocarditis in a patient with hypertrophic cardiomyopathy: reduction in ventricular afterload by disopyramide.
    Japanese circulation journal, 1999, Volume: 63, Issue:8

    Topics: Acute Disease; Aged; Cardiomyopathy, Hypertrophic; Coronary Angiography; Disopyramide; Echocardiogra

1999