disopyramide has been researched along with Thrombocytopenia in 2 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Thrombocytopenia: A subnormal level of BLOOD PLATELETS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This case report shows that disopyramide can have the serious side effect of hepatocellular toxicity and provides evidence of the association of hepatocellular damage and disseminated intravascular coagulation." | 5.26 | Disopyramide hepatotoxicity and disseminated intravascular coagulation. ( Doody, PT, 1982) |
| "Amrubicin is a novel synthetic 9-aminoanthracycline derivative and is converted enzymatically to its C-13 hydroxy metabolite, amrubicinol, whose cytotoxic activity is 10-100 times that of amrubicin." | 2.72 | Phase I and pharmacokinetic study of amrubicin, a synthetic 9-aminoanthracycline, in patients with refractory or relapsed lung cancer. ( Fujii, S; Hamada, A; Kishi, H; Matsunaga, Y; Mori, I; Okamoto, I; Saito, H; Sasaki, J; Semba, H; Uramoto, H; Yamagata, H, 2006) |
| " This case report shows that disopyramide can have the serious side effect of hepatocellular toxicity and provides evidence of the association of hepatocellular damage and disseminated intravascular coagulation." | 1.26 | Disopyramide hepatotoxicity and disseminated intravascular coagulation. ( Doody, PT, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okamoto, I | 1 |
| Hamada, A | 1 |
| Matsunaga, Y | 1 |
| Sasaki, J | 1 |
| Fujii, S | 1 |
| Uramoto, H | 1 |
| Yamagata, H | 1 |
| Mori, I | 1 |
| Kishi, H | 1 |
| Semba, H | 1 |
| Saito, H | 1 |
| Doody, PT | 1 |
1 trial available for disopyramide and Thrombocytopenia
| Article | Year |
|---|---|
Phase I and pharmacokinetic study of amrubicin, a synthetic 9-aminoanthracycline, in patients with refractory or relapsed lung cancer.
Topics: Aged; Anthracyclines; Antineoplastic Agents; Area Under Curve; Atrial Fibrillation; Carcinoma, Non-S | 2006 |
1 other study available for disopyramide and Thrombocytopenia
| Article | Year |
|---|---|
Disopyramide hepatotoxicity and disseminated intravascular coagulation.
Topics: Chemical and Drug Induced Liver Injury; Disopyramide; Disseminated Intravascular Coagulation; Female | 1982 |