Page last updated: 2024-10-26

disopyramide and Syndrome

disopyramide has been researched along with Syndrome in 10 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"Administration of disopyramide was effective in preventing syncope."4.02Frequent occurrence of postbreakfast syncope due to carotid sinus syndrome after surgery for hypopharyngeal cancer: A case report. ( Ando, Y; Fujita, N; Hashimoto, K; Obuchi, Y; Ono, Y; Sano, A; Tanaka, Y; Tatsushima, D; Tomifuji, M; Watanabe, S; Yanagawa, R, 2021)
"Brugada syndrome is characterized by an ST segment elevation in leads V1-V3 and a high incidence of ventricular fibrillation (VF)."2.69Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. ( Aihara, N; Antzelevitch, C; Kamakura, S; Kurita, T; Shimizu, W; Sunagawa, K; Suyama, K; Taguchi, A; Takaki, H, 2000)
"Disopyramide was given to 5 patients resulting in suppression of the arrhythmia and relief of symptoms."1.26Atrial bigeminy with block associated with bradycardia and paroxysmal atrial fibrillation -- an important variant of the tachycardia-bradycardia syndrome. ( Camm, AJ; Spurrell, RA; Ward, DE; Washington, HG, 1979)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's2 (20.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Ando, Y1
Hashimoto, K1
Sano, A1
Fujita, N1
Yanagawa, R1
Ono, Y1
Obuchi, Y1
Tatsushima, D1
Watanabe, S1
Tomifuji, M1
Tanaka, Y1
Mizobuchi, M1
Enjoji, Y1
Yamamoto, R1
Ono, T1
Funatsu, A1
Kambayashi, D1
Kobayashi, T1
Nakamura, S1
Takagi, M1
Aihara, N2
Kuribayashi, S1
Taguchi, A2
Kurita, T2
Suyama, K2
Kamakura, S2
Takamiya, M1
McPate, MJ1
Duncan, RS1
Witchel, HJ1
Hancox, JC1
Dumaine, R1
Antzelevitch, C2
Miyazaki, T1
Mitamura, H1
Miyoshi, S1
Soejima, K1
Aizawa, Y2
Ogawa, S1
Chinushi, M1
Ogawa, Y1
Shiba, M1
Takahashi, K1
Shimizu, W1
Takaki, H1
Sunagawa, K1
Washington, HG1
Ward, DE1
Camm, AJ1
Spurrell, RA1
den Dulk, K1
Lindemans, FW1
Brugada, P1
Smeets, JL1
Wellens, HJ1

Trials

1 trial available for disopyramide and Syndrome

ArticleYear
Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome.
    Journal of cardiovascular electrophysiology, 2000, Volume: 11, Issue:12

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Disopyramide; Electrocardiography; Flecain

2000

Other Studies

9 other studies available for disopyramide and Syndrome

ArticleYear
Frequent occurrence of postbreakfast syncope due to carotid sinus syndrome after surgery for hypopharyngeal cancer: A case report.
    Medicine, 2021, May-21, Volume: 100, Issue:20

    Topics: Aged; Anastomosis, Surgical; Breakfast; Carotid Sinus; Deglutition; Disopyramide; Electrocardiograph

2021
Nifekalant and disopyramide in a patient with short QT syndrome: evaluation of pharmacological effects and electrophysiological properties.
    Pacing and clinical electrophysiology : PACE, 2008, Volume: 31, Issue:9

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Body Surface Potential Mapping; Disopyramide; Humans; M

2008
Abnormal response to sodium channel blockers in patients with Brugada syndrome: augmented localised wall motion abnormalities in the right ventricular outflow tract region detected by electron beam computed tomography.
    Heart (British Cardiac Society), 2003, Volume: 89, Issue:2

    Topics: Adult; Analysis of Variance; Anti-Arrhythmia Agents; Bundle-Branch Block; Case-Control Studies; Diso

2003
Disopyramide is an effective inhibitor of mutant HERG K+ channels involved in variant 1 short QT syndrome.
    Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; CHO Cells; Cricetinae; Cricetulus; Death, Sud

2006
Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome?
    Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:3

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Disopyramide; Drug Interaction

2006
Autonomic and antiarrhythmic drug modulation of ST segment elevation in patients with Brugada syndrome.
    Journal of the American College of Cardiology, 1996, Volume: 27, Issue:5

    Topics: Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Humans;

1996
Discrepant drug action of disopyramide on ECG abnormalities and induction of ventricular arrhythmias in a patient with Brugada syndrome.
    Journal of electrocardiology, 1997, Volume: 30, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Dose-Response Relationship,

1997
Atrial bigeminy with block associated with bradycardia and paroxysmal atrial fibrillation -- an important variant of the tachycardia-bradycardia syndrome.
    Clinical cardiology, 1979, Volume: 2, Issue:2

    Topics: Adult; Aged; Atrial Fibrillation; Bradycardia; Cardiac Complexes, Premature; Disopyramide; Electroca

1979
Pacemaker syndrome with AAI rate variable pacing: importance of atrioventricular conduction properties, medication, and pacemaker programmability.
    Pacing and clinical electrophysiology : PACE, 1988, Volume: 11, Issue:8

    Topics: Aged; Atrioventricular Node; Bradycardia; Disopyramide; Dizziness; Equipment Design; Exercise; Heart

1988