disopyramide has been researched along with Sick Sinus Node Syndrome in 9 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied changes in atrial pacing threshold after termination of atrial fibrillation (AF) by acute administration of disopyramide phosphate (DP) to elucidate the suitable setting for atrial pacing output before AF termination." | 7.73 | Increased AAI mode pacing threshold after termination of atrial fibrillation by acute administration of disopyramide phosphate. ( Anzawa, R; Ishikawa, S; Mochizuki, S; Okazaki, F; Tanaka, Y, 2006) |
| "This study suggests that the patients showing bradycardia dependent QT prolongation are also more markedly affected by disopyramide and that abnormal potassium channel may be the underlying mechanism." | 7.70 | Relation between bradycardia dependent long QT syndrome and QT prolongation by disopyramide in humans. ( Abe, A; Aizawa, Y; Chinushi, M; Furushima, H; Niwano, S; Ohhira, K, 1998) |
| "Since disopyramide was introduced 5 years ago, the therapeutic spectrum of this drug in treating patients with ventricular and atrial arrhythmias has been found to be similar to that of the other type I antiarrhythmic drugs, quinidine and procainamide." | 4.76 | Disopyramide. ( Desai, J; Morady, F; Scheinman, MM, 1982) |
| "We studied changes in atrial pacing threshold after termination of atrial fibrillation (AF) by acute administration of disopyramide phosphate (DP) to elucidate the suitable setting for atrial pacing output before AF termination." | 3.73 | Increased AAI mode pacing threshold after termination of atrial fibrillation by acute administration of disopyramide phosphate. ( Anzawa, R; Ishikawa, S; Mochizuki, S; Okazaki, F; Tanaka, Y, 2006) |
| "This study suggests that the patients showing bradycardia dependent QT prolongation are also more markedly affected by disopyramide and that abnormal potassium channel may be the underlying mechanism." | 3.70 | Relation between bradycardia dependent long QT syndrome and QT prolongation by disopyramide in humans. ( Abe, A; Aizawa, Y; Chinushi, M; Furushima, H; Niwano, S; Ohhira, K, 1998) |
| "Torsades de pointes was induced following ventricular paced beats and suppressed by cessation of disopyramide in all or by setting a higher pacing rate in one." | 1.29 | Torsades de pointes in paced patients with sick sinus syndrome after disopyramide administration. ( Fujito, T; Hayashi, T; Inoue, T; Kimura, Y; Morooka, S; Sakai, Y; Satoh, T; Takabatake, Y; Takayanagi, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anzawa, R | 1 |
| Ishikawa, S | 1 |
| Tanaka, Y | 1 |
| Okazaki, F | 1 |
| Mochizuki, S | 1 |
| Suzuki, S | 1 |
| Kasanuki, H | 1 |
| Onishi, S | 1 |
| Tanaka, T | 2 |
| Hirosawa, K | 1 |
| Abe, M | 1 |
| Kohashi, K | 1 |
| Taniguchi, T | 1 |
| Matsuda, M | 1 |
| Morady, F | 1 |
| Scheinman, MM | 1 |
| Desai, J | 1 |
| Kimura, Y | 1 |
| Takayanagi, K | 1 |
| Sakai, Y | 1 |
| Satoh, T | 1 |
| Fujito, T | 1 |
| Inoue, T | 1 |
| Hayashi, T | 1 |
| Morooka, S | 1 |
| Takabatake, Y | 1 |
| Furushima, H | 1 |
| Niwano, S | 1 |
| Chinushi, M | 1 |
| Ohhira, K | 1 |
| Abe, A | 1 |
| Aizawa, Y | 1 |
| Ishikawa, T | 1 |
| Sumita, S | 1 |
| Kimura, K | 1 |
| Kikuchi, M | 1 |
| Kosuge, M | 1 |
| Endo, T | 1 |
| Sugano, T | 1 |
| Sigemasa, T | 1 |
| Usui, T | 1 |
| Umemura, S | 1 |
| Fox, K | 1 |
| Evans, T | 1 |
| Rowland, E | 1 |
| Krikler, D | 1 |
| Arlotti, M | 1 |
| Ambrosini, F | 1 |
| Musacchio, E | 1 |
| Manfredini, R | 1 |
| Duca, GP | 1 |
| Lotto, A | 1 |
| Augsten, G | 1 |
| Rostock, KJ | 1 |
| Pfeiffer, D | 1 |
| Rathgen, K | 1 |
1 review available for disopyramide and Sick Sinus Node Syndrome
| Article | Year |
|---|---|
Disopyramide.
Topics: Arrhythmias, Cardiac; Disopyramide; Drug Interactions; Electrophysiology; Heart; Heart Block; Humans | 1982 |
8 other studies available for disopyramide and Sick Sinus Node Syndrome
| Article | Year |
|---|---|
Increased AAI mode pacing threshold after termination of atrial fibrillation by acute administration of disopyramide phosphate.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Disopyramide; Female; | 2006 |
[Electrophysiologic and hemodynamic effects of disopyramide phosphate (author's transl)].
Topics: Adolescent; Adult; Aged; Cardiac Output; Disopyramide; Female; Heart Rate; Hemodynamics; Humans; Mal | 1981 |
Torsades de pointes in paced patients with sick sinus syndrome after disopyramide administration.
Topics: Aged; Cardiac Pacing, Artificial; Disopyramide; Electrocardiography; Female; Humans; Potassium; Sick | 1994 |
Relation between bradycardia dependent long QT syndrome and QT prolongation by disopyramide in humans.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Bradycardia; Cardiac Pacing, Artificial; Dis | 1998 |
Sinus node recovery time assessment by the overdrive suppression test employing an intravenous injection of disopyramide phosphate.
Topics: Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Electrocardiography; Female; | 2000 |
'Bradycardia-tachycardia' syndrome 8 yr after correction of Fallot's tetralogy.
Topics: Adolescent; Arrhythmias, Cardiac; Atrial Flutter; Bradycardia; Child; Child, Preschool; Death, Sudde | 1979 |
[Electrophysiological and clinical effects of disopyramide in atrial arrhythmic disease in the initial stage].
Topics: Adult; Aged; Aged, 80 and over; Disopyramide; Drug Evaluation; Electrocardiography; Female; Humans; | 1988 |
[Differential therapeutic problems in sinus node syndrome--drug or electrical therapy?].
Topics: Anti-Arrhythmia Agents; Atropine; Bundle of His; Cardiac Glycosides; Disopyramide; Drug Therapy, Com | 1986 |