disopyramide has been researched along with Pregnancy in 15 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effect of disopyramide on uterine contractions during pregnancy, the drug was given for 48 hours to 10 women with indications for labor induction." | 9.06 | The effect of disopyramide on uterine contractions during pregnancy. ( Diamant, YZ; Gal, M; Graff, E; Hornstein, E; Keren, A; Rosenak, D; Shaia, M; Stern, S; Tadmor, OP; Yaffe, H, 1990) |
| " This is the first case report of preterm labor and abruptio placentae following the administration of disopyramide during pregnancy." | 7.70 | Preterm labor and accidental hemorrhage after disopyramide therapy in pregnancy. A case report. ( Abbi, M; Kriplani, A; Singh, B, 1999) |
| " This is the first case report of preterm labor and abruptio placentae following the administration of disopyramide during pregnancy." | 3.70 | Preterm labor and accidental hemorrhage after disopyramide therapy in pregnancy. A case report. ( Abbi, M; Kriplani, A; Singh, B, 1999) |
| " Special consideration, however, must be given with regard to drug selection and dosage in order to avoid adverse effects on the mother and fetus." | 2.36 | Antiarrhythmic drug therapy during pregnancy. ( Elkayam, U; Frishman, W; Rotmensch, HH, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (73.33) | 18.7374 |
| 1990's | 3 (20.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shima, Y | 1 |
| Baba, C | 1 |
| Fujita, A | 1 |
| Kanoh, M | 1 |
| Watanabe, M | 1 |
| Ogawa, S | 1 |
| Kawase, R | 1 |
| Shin, S | 1 |
| Rotmensch, HH | 1 |
| Elkayam, U | 1 |
| Frishman, W | 1 |
| Ueland, K | 1 |
| McAnulty, JH | 1 |
| Ueland, FR | 1 |
| Metcalfe, J | 1 |
| Abbi, M | 1 |
| Kriplani, A | 1 |
| Singh, B | 1 |
| Shaxted, EJ | 1 |
| Milton, PJ | 1 |
| Leonard, RF | 1 |
| Braun, TE | 1 |
| Levy, AM | 1 |
| Laidlaw, JC | 1 |
| Echizen, H | 1 |
| Nakura, M | 1 |
| Saotome, T | 1 |
| Minoura, S | 1 |
| Ishizaki, T | 1 |
| Tadmor, OP | 1 |
| Keren, A | 1 |
| Rosenak, D | 1 |
| Gal, M | 1 |
| Shaia, M | 1 |
| Hornstein, E | 1 |
| Yaffe, H | 1 |
| Graff, E | 1 |
| Stern, S | 1 |
| Diamant, YZ | 1 |
| Ellsworth, AJ | 1 |
| Horn, JR | 1 |
| Raisys, VA | 1 |
| Miyagawa, LA | 1 |
| Bell, JL | 1 |
| Wood, M | 1 |
| Hirotsu, I | 1 |
| Kihara, T | 1 |
| Hattori, Y | 1 |
| Hatta, M | 1 |
| Hirose, N | 1 |
| Ishihara, T | 1 |
| Satoh, F | 1 |
| Hoppu, K | 1 |
| Neuvonen, PJ | 1 |
| Korte, T | 1 |
| Fossati, C | 1 |
| MacKintosh, D | 1 |
| Buchanan, N | 1 |
4 reviews available for disopyramide and Pregnancy
| Article | Year |
|---|---|
Antiarrhythmic drug therapy during pregnancy.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Digitalis | 1983 |
Special considerations in the use of cardiovascular drugs.
Topics: Anti-Arrhythmia Agents; Anticoagulants; Cardiac Glycosides; Cardiovascular Agents; Disopyramide; Diu | 1981 |
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca | 1986 |
[Pharmacologic problems with teratogenic drugs].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anesthetics; Anti-Arrhythmia Agents; Anticonvu | 1985 |
2 trials available for disopyramide and Pregnancy
| Article | Year |
|---|---|
Clinical studies of Norpace (Part VIII).
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Clinical Trials as Topic; D | 1975 |
The effect of disopyramide on uterine contractions during pregnancy.
Topics: Adult; Disopyramide; Double-Blind Method; Female; Heart Rate, Fetal; Humans; Labor, Induced; Pregnan | 1990 |
9 other studies available for disopyramide and Pregnancy
| Article | Year |
|---|---|
Simultaneous supraventricular tachycardias in both fetuses of a twin gestation.
Topics: Administration, Oral; Adult; Anti-Arrhythmia Agents; Digoxin; Disopyramide; Drug Therapy, Combinatio | 2004 |
Preterm labor and accidental hemorrhage after disopyramide therapy in pregnancy. A case report.
Topics: Abruptio Placentae; Adult; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Female; Humans | 1999 |
Disopyramide in pregnancy: a case report.
Topics: Adult; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Female; Heart Rate; Humans; Pregnanc | 1979 |
Initiation of uterine contractions by disopyramide during pregnancy.
Topics: Adult; Arrhythmias, Cardiac; Disopyramide; Female; Heart Valve Diseases; Humans; Mitral Valve; Pregn | 1978 |
Plasma protein binding of disopyramide in pregnant and postpartum women, and in neonates and their mothers.
Topics: Adult; Blood Proteins; Disopyramide; Female; Fluorescence Polarization; Fluorescent Antibody Techniq | 1990 |
Disopyramide and N-monodesalkyl disopyramide in serum and breast milk.
Topics: Adult; Disopyramide; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Hu | 1989 |
General pharmacological studies on N-(2,6-dimethylphenyl)-8-pyrrolizidineacetamide hydrochloride hemihydrate. 2nd communication: effect on the peripheral nervous system and peripheral organs.
Topics: Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Capillary Permeability; Chemical Phenomen | 1988 |
Disopyramide and breast feeding.
Topics: Adult; Breast Feeding; Disopyramide; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mil | 1986 |
Excretion of disopyramide in human breast milk.
Topics: Adult; Disopyramide; Female; Humans; Milk, Human; Pregnancy | 1985 |