disopyramide has been researched along with Myotonic Dystrophy in 2 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial." | 9.05 | A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy. ( Finlay, M, 1982) |
| "Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial." | 5.05 | A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy. ( Finlay, M, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Finlay, M | 1 |
| Kwieciński, H | 1 |
| Ryniewicz, B | 1 |
| Ostrzycki, A | 1 |
2 trials available for disopyramide and Myotonic Dystrophy
| Article | Year |
|---|---|
A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Disopyramide; Female; Humans; | 1982 |
Treatment of myotonia with antiarrhythmic drugs.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Drug Admi | 1992 |