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disopyramide and Myotonic Dystrophy

disopyramide has been researched along with Myotonic Dystrophy in 2 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.

Research Excerpts

ExcerptRelevanceReference
"Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial."9.05A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy. ( Finlay, M, 1982)
"Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial."5.05A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy. ( Finlay, M, 1982)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Finlay, M1
KwieciƄski, H1
Ryniewicz, B1
Ostrzycki, A1

Trials

2 trials available for disopyramide and Myotonic Dystrophy

ArticleYear
A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Disopyramide; Female; Humans;

1982
Treatment of myotonia with antiarrhythmic drugs.
    Acta neurologica Scandinavica, 1992, Volume: 86, Issue:4

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Drug Admi

1992