disopyramide has been researched along with Muscle Contraction in 13 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial." | 9.05 | A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy. ( Finlay, M, 1982) |
| " Acetylcholine, prostaglandin F2-alpha, potassium chloride, barium chloride, adenosine triphosphate and Ca2+ were used as agonists for detrusor muscle contraction." | 7.67 | Effects of disopyramide on detrusor muscle contraction: in vitro experiment and report of 3 cases with disopyramide-induced urinary retention. ( Gotoh, M; Kato, K; Kondo, A; Saito, M, 1987) |
| "Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial." | 5.05 | A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy. ( Finlay, M, 1982) |
| " Acetylcholine, prostaglandin F2-alpha, potassium chloride, barium chloride, adenosine triphosphate and Ca2+ were used as agonists for detrusor muscle contraction." | 3.67 | Effects of disopyramide on detrusor muscle contraction: in vitro experiment and report of 3 cases with disopyramide-induced urinary retention. ( Gotoh, M; Kato, K; Kondo, A; Saito, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stout, DM | 1 |
| Matier, WL | 1 |
| Barcelon-Yang, C | 1 |
| Reynolds, RD | 1 |
| Brown, BS | 1 |
| Nelson, WL | 1 |
| Sneed, CK | 1 |
| Giacomini, KM | 2 |
| Giacomini, JC | 1 |
| Stauss, J | 1 |
| Blaschke, TF | 2 |
| Cox, BM | 2 |
| Byrne, AJ | 1 |
| Healy, TE | 1 |
| Mahmoodi, V | 1 |
| Poole, TR | 1 |
| Finlay, M | 1 |
| Fernández del Pozo, B | 1 |
| Pérez-Vizcaíno, F | 1 |
| Fernández, C | 1 |
| Zaragozá, F | 1 |
| Tamargo, J | 1 |
| Elliott, RA | 1 |
| Hudman, D | 1 |
| Terry, T | 1 |
| Sandhu, D | 1 |
| Norman, RI | 1 |
| Koutsoviti-Papadopoulou, M | 1 |
| Nikolaidis, E | 1 |
| Batzias, GC | 1 |
| Kounenis, G | 1 |
| Endou, M | 1 |
| Jones, SV | 1 |
| Marshall, IG | 1 |
| Konishi, T | 1 |
| Kadoya, M | 1 |
| Ikeguchi, S | 1 |
| Sakai, K | 1 |
| Tamamura, T | 1 |
| Kawai, C | 1 |
| Baurain, M | 1 |
| Barvais, L | 1 |
| d'Hollander, A | 1 |
| Hennart, D | 1 |
| Gotoh, M | 1 |
| Kato, K | 1 |
| Saito, M | 1 |
| Kondo, A | 1 |
1 trial available for disopyramide and Muscle Contraction
| Article | Year |
|---|---|
A comparative study of disopyramide and procainamide in the treatment of myotonia in myotonic dystrophy.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Disopyramide; Female; Humans; | 1982 |
12 other studies available for disopyramide and Muscle Contraction
| Article | Year |
|---|---|
Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 2. Amides.
Topics: Amides; Animals; Anti-Arrhythmia Agents; Chemical Phenomena; Chemistry; Dogs; Electric Stimulation; | 1984 |
Synthesis and anticholinergic properties of the enantiomers of 4-(isopropylamino)-2-(2-pyridyl)-2-phenylbutyramide, the mono-N-dealkylated metabolite of disopyramide.
Topics: Acetylcholine; Animals; Chemical Phenomena; Chemistry; Disopyramide; Dose-Response Relationship, Dru | 1981 |
Disopyramide anticholinergic action.
Topics: Abdominal Muscles; Animals; Carbachol; Disopyramide; Dose-Response Relationship, Drug; Guinea Pigs; | 1981 |
Comparative anticholinergic potencies of R- and S- disopyramide in longitudinal muscle strips from guinea pig ileum.
Topics: Acetylcholine; Animals; Disopyramide; Electric Stimulation; Guinea Pigs; Histamine; Ileum; In Vitro | 1980 |
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle.
Topics: Animals; Anti-Arrhythmia Agents; Aorta; Desipramine; Disopyramide; Flecainide; Imipramine; In Vitro | 1997 |
Inhibition of isolated rat and human detrusor muscle contraction by disopyramide.
Topics: Aged; Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Disopyramide; Electric Stimulation; Fema | 2000 |
Cisapride reverses the anticholinergic effect of disopyramide on the isolated guinea-pig urinary bladder.
Topics: Acetylcholine; Animals; Cholinergic Antagonists; Cisapride; Disopyramide; Dose-Response Relationship | 2002 |
[Pharmacological analysis of drug interactions of disopyramide and its congeners with peripheral muscarinic acetylcholine receptors].
Topics: Animals; Binding, Competitive; Carbachol; Disopyramide; Drug Interactions; Female; Guinea Pigs; In V | 1991 |
Non-competitive effects of disopyramide at the neuromuscular junction: evidence for endplate ion channel block.
Topics: Animals; Carbachol; Chickens; Disopyramide; Dose-Response Relationship, Drug; In Vitro Techniques; I | 1987 |
Combined effect of disopyramide and bethanechol: use of bethanechol to prevent anticholinergic side effects of disopyramide without reduction of antiarrhythmic efficacy.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bethanechol Compounds; Blood Pre | 1989 |
Impairment of the antagonism of vecuronium-induced paralysis and intra-operative disopyramide administration.
Topics: Atropine; Disopyramide; Drug Interactions; Humans; Intraoperative Care; Male; Middle Aged; Muscle Co | 1989 |
Effects of disopyramide on detrusor muscle contraction: in vitro experiment and report of 3 cases with disopyramide-induced urinary retention.
Topics: Acetylcholine; Adenosine Triphosphate; Aged; Aged, 80 and over; Animals; Barium; Barium Compounds; C | 1987 |