disopyramide has been researched along with Liver Cirrhosis in 4 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The plasma protein binding of disopyramide (D) was determined in seven patients with cirrhosis, six with nephrotic syndrome, and seven healthy subjects." | 7.67 | Protein binding of disopyramide in liver cirrhosis and in nephrotic syndrome. ( Echizen, H; Ishizaki, T; Saima, S; Umeda, N, 1986) |
| "The plasma protein binding of disopyramide (D) was determined in seven patients with cirrhosis, six with nephrotic syndrome, and seven healthy subjects." | 3.67 | Protein binding of disopyramide in liver cirrhosis and in nephrotic syndrome. ( Echizen, H; Ishizaki, T; Saima, S; Umeda, N, 1986) |
| " The clinical implication of the present findings appear to be that the dosage of disopyramide should be reduced by 25% when it is given intravenously to patients with decreased hepatic function." | 1.27 | Kinetics of disopyramide in decreased hepatic function. ( Angelo, HR; Balsløv, S; Bonde, J; Graudal, NA; Kampmann, JP; Pedersen, LE; Svendsen, TL, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Belpaire, FM | 1 |
| Bogaert, MG | 1 |
| Echizen, H | 1 |
| Saima, S | 1 |
| Umeda, N | 1 |
| Ishizaki, T | 1 |
| Bonde, J | 2 |
| Graudal, NA | 2 |
| Pedersen, LE | 2 |
| Balsløv, S | 1 |
| Angelo, HR | 1 |
| Svendsen, TL | 1 |
| Kampmann, JP | 2 |
| Backer, NV | 1 |
| Hansen, JE | 1 |
4 other studies available for disopyramide and Liver Cirrhosis
| Article | Year |
|---|---|
Binding of alfentanil to human alpha 1-acid glycoprotein, albumin and serum.
Topics: Adult; Aged; Alfentanil; Arthritis, Rheumatoid; Disopyramide; Female; Humans; Kidney Failure, Chroni | 1991 |
Protein binding of disopyramide in liver cirrhosis and in nephrotic syndrome.
Topics: Adult; Aged; Analysis of Variance; Blood Proteins; Disopyramide; Female; Fluorescence Polarization; | 1986 |
Kinetics of disopyramide in decreased hepatic function.
Topics: Adult; Aged; Disopyramide; Female; Half-Life; Humans; Kinetics; Liver Cirrhosis; Liver Function Test | 1986 |
Quantitative and qualitative binding characteristics of disopyramide in serum from patients with decreased renal and hepatic function.
Topics: Adult; Aged; Coronary Disease; Disopyramide; Female; Humans; Kidney Failure, Chronic; Liver Cirrhosi | 1987 |