disopyramide has been researched along with Left Ventricular Outflow Obstruction in 21 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This combination allows adequate dosing of disopyramide to achieve therapeutic goals." | 2.53 | Drug Therapy for Hypertrophic Cardiomypathy: Physiology and Practice. ( Sherrid, MV, 2016) |
| "Disopyramide is a safe and effective treatment for LVOTO-related symptoms in childhood obstructive HCM." | 1.91 | Disopyramide is a safe and effective treatment for children with obstructive hypertrophic cardiomyopathy. ( Boleti, O; Cervi, E; Field, E; Kaski, JP; Norrish, G; Topriceanu, CC, 2023) |
| "Treatment with bisoprolol was well-tolerated and effective in relieving obstruction and improving symptoms in a significant proportion of patients with symptomatic obstructive HCM." | 1.72 | Bisoprolol for treatment of symptomatic patients with obstructive hypertrophic cardiomyopathy. The BASIC (bisoprolol AS therapy in hypertrophic cardiomyopathy) study. ( Caiazza, M; Calabrò, P; Cirillo, A; Dongiglio, F; Franco, F; Fusco, A; Limongelli, G; Lioncino, M; Mazzella, M; Monda, E; Moscarella, E; Pacileo, G; Palmiero, G; Rubino, M; Sepe, J; Verrillo, F, 2022) |
| "When severe COPD and obstructive hypertrophic cardiomyopathy (HCM) coexist, management is challenging and complex." | 1.35 | Oral disopyramide for the acute treatment of severe outflow obstruction in hypertrophic cardiomyopathy in the ICU setting. ( Sherrid, MV; Sirak, TE, 2008) |
| "During surgery, dynamic left ventricular outflow obstruction (LVOT) can potentially occur frequently, but diagnosis may be less frequent." | 1.31 | An intraoperative diagnosis of dynamic left ventricular outflow tract obstruction using transesophageal echocardiography leads to the treatment with intravenous disopyramide. ( Ashidagawa, M; Koide, Y; Ohara, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Monda, E | 1 |
| Lioncino, M | 1 |
| Palmiero, G | 1 |
| Franco, F | 1 |
| Rubino, M | 1 |
| Cirillo, A | 1 |
| Verrillo, F | 1 |
| Fusco, A | 1 |
| Caiazza, M | 1 |
| Mazzella, M | 1 |
| Moscarella, E | 1 |
| Dongiglio, F | 1 |
| Sepe, J | 1 |
| Pacileo, G | 1 |
| Calabrò, P | 1 |
| Limongelli, G | 1 |
| Topriceanu, CC | 1 |
| Field, E | 1 |
| Boleti, O | 1 |
| Cervi, E | 1 |
| Kaski, JP | 1 |
| Norrish, G | 1 |
| Hori, Y | 1 |
| Fujimoto, E | 1 |
| Nishikawa, Y | 1 |
| Nakamura, T | 1 |
| Sorajja, P | 1 |
| Ommen, SR | 2 |
| Nishimura, RA | 2 |
| Haruki, S | 2 |
| Minami, Y | 3 |
| Suzuki, A | 1 |
| Hagiwara, N | 3 |
| Sherrid, MV | 4 |
| Kajimoto, K | 2 |
| Kawana, M | 2 |
| Chen, F | 1 |
| Hanaoka, N | 1 |
| Hasegawa, S | 1 |
| Fujinaga, T | 1 |
| Shoji, T | 1 |
| Sakai, H | 1 |
| Bando, T | 1 |
| Pasquale, F | 1 |
| Tomé-Esteban, MT | 1 |
| Morgagni, R | 1 |
| Elliott, P | 1 |
| Yashiro, B | 1 |
| Suzuki, T | 1 |
| Ranasinghe, I | 1 |
| Yeoh, T | 1 |
| Yiannikas, J | 1 |
| Miyaji, K | 1 |
| Matsubara, H | 2 |
| Kajiya, M | 1 |
| Tani, Y | 1 |
| Nakamura, K | 1 |
| Morita, H | 1 |
| Emori, T | 1 |
| Date, H | 1 |
| Ohe, T | 2 |
| Elesber, A | 1 |
| Rihal, CS | 1 |
| Schaff, HV | 1 |
| Holmes, DR | 1 |
| Sirak, TE | 1 |
| Nakatani, S | 1 |
| Nagata, S | 1 |
| Ishikura, F | 1 |
| Katagiri, Y | 1 |
| Miyatake, K | 1 |
| Kimball, BP | 1 |
| Bui, S | 1 |
| Wigle, ED | 1 |
| Gunsburg, DZ | 1 |
| Pearle, G | 1 |
| Sakai, Y | 1 |
| Hayashi, Y | 1 |
| Tomobuchi, Y | 1 |
| Hano, T | 1 |
| Nishio, I | 1 |
| Niki, K | 1 |
| Sugawara, M | 1 |
| Tanino, S | 1 |
| Iwade, K | 1 |
| Hosoda, S | 1 |
| Kasanuki, H | 1 |
| Ashidagawa, M | 1 |
| Ohara, M | 1 |
| Koide, Y | 1 |
| Duncan, WJ | 1 |
| Tyrrell, MJ | 1 |
| Bharadwaj, BB | 1 |
1 review available for disopyramide and Left Ventricular Outflow Obstruction
| Article | Year |
|---|---|
Drug Therapy for Hypertrophic Cardiomypathy: Physiology and Practice.
Topics: Animals; Cardiomyopathy, Hypertrophic; Disopyramide; Electrocardiography; Humans; Hypertension; Vent | 2016 |
1 trial available for disopyramide and Left Ventricular Outflow Obstruction
| Article | Year |
|---|---|
Salutary effect of disopyramide on left ventricular diastolic function in hypertrophic obstructive cardiomyopathy.
Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Cardiac Catheterization; Cardiomyopathy, Hypertro | 1995 |
19 other studies available for disopyramide and Left Ventricular Outflow Obstruction
| Article | Year |
|---|---|
Bisoprolol for treatment of symptomatic patients with obstructive hypertrophic cardiomyopathy. The BASIC (bisoprolol AS therapy in hypertrophic cardiomyopathy) study.
Topics: Adult; Bisoprolol; Cardiomyopathy, Hypertrophic; Disopyramide; Humans; Retrospective Studies; Ventri | 2022 |
Disopyramide is a safe and effective treatment for children with obstructive hypertrophic cardiomyopathy.
Topics: Adolescent; Adult; Cardiomyopathy, Hypertrophic; Child; Child, Preschool; Disopyramide; Echocardiogr | 2023 |
Left ventricular outflow tract pressure gradient changes after carvedilol-disopyramide cotherapy in a cat with hypertrophic obstructive cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomyopathy, Hypertrophic; Carvedilol; Cat Diseases; Cats; | 2020 |
Symptomatic obstructive hypertrophic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Aged; Cardiomyopathy, Hypertrophic; Diagnosis, Differential; Disease-Fr | 2013 |
Effects of flecainide on left ventricular pressure gradient and symptoms in obstructive hypertrophic cardiomyopathy: a comparison of flecainide and disopyramide.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Dose-Respo | 2015 |
Synergistic effect of dual chamber pacing and disopyramide in obstructive hypertrophic cardiomyopathy.
Topics: Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiomyopathy, Hypertrophic; Combined Modality | 2010 |
Right ventricular outflow tract obstruction after bilateral lung transplantation.
Topics: Adult; Atenolol; Cardiac Surgical Procedures; Cardiovascular Agents; Disopyramide; Drug Therapy, Com | 2009 |
Provokable left ventricular outflow tract obstruction in a patient without hypertrophy.
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Atenolol; Cardiac Pacing, Artificial; Diagnostic Imaging; D | 2009 |
Possible acute and chronic synergistic effect of dual chamber pacing and disopyramide in obstructive hypertrophic cardiomyopathy: a case report.
Topics: Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiomyopathy, Hypertrophic; Combined Mod | 2010 |
Negative ionotropic agents for the treatment of left ventricular outflow tract obstruction due to sigmoid septum and concentric left ventricular hypertrophy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Cardiomyopathy, | 2011 |
Failure of disopyramide to improve right ventricular outflow tract obstruction after living-donor lobar lung transplantation.
Topics: Adult; Anti-Arrhythmia Agents; Atenolol; Cardiac Catheterization; Disopyramide; Echocardiography; Fe | 2004 |
Utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Calcium Channel Blocke | 2008 |
Oral disopyramide for the acute treatment of severe outflow obstruction in hypertrophic cardiomyopathy in the ICU setting.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Dose-Respo | 2008 |
Acute dose-response effects of intravenous disopyramide in hypertrophic obstructive cardiomyopathy.
Topics: Adolescent; Adult; Aged; Cardiomyopathy, Hypertrophic; Disopyramide; Dose-Response Relationship, Dru | 1993 |
Mid-systolic drop in left ventricular ejection velocity in obstructive hypertrophic cardiomyopathy--the lobster claw abnormality.
Topics: Acceleration; Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Blood Flow Velocity; Calciu | 1997 |
Dynamic outflow obstruction due to the transient extensive left ventricular wall motion abnormalities caused by acute myocarditis in a patient with hypertrophic cardiomyopathy: reduction in ventricular afterload by disopyramide.
Topics: Acute Disease; Aged; Cardiomyopathy, Hypertrophic; Coronary Angiography; Disopyramide; Echocardiogra | 1999 |
An equation to predict the changes in peak left ventricular pressure in hypertrophic obstructive cardiomyopathy after treatment: application to the administration of disopyramide.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Disopyra | 1999 |
An intraoperative diagnosis of dynamic left ventricular outflow tract obstruction using transesophageal echocardiography leads to the treatment with intravenous disopyramide.
Topics: Anti-Arrhythmia Agents; Arthroplasty, Replacement, Knee; Disopyramide; Echocardiography, Transesopha | 2002 |
Disopyramide as a negative inotrope in obstructive cardiomyopathy in children.
Topics: Cardiomyopathy, Hypertrophic; Carnitine; Child; Disopyramide; Ductus Arteriosus, Patent; Echocardiog | 1991 |