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disopyramide and Left Ventricular Hypertrophy

disopyramide has been researched along with Left Ventricular Hypertrophy in 2 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Research Excerpts

ExcerptRelevanceReference
"In a rat model of chronic pressure overload induced by abdominal aortic banding, we evaluated the effects on left ventricular hypertrophy (LVH) of the propranolol isomers, L-propranolol and D-propranolol, which compared to L-isomer is approximately 50-fold less potent as a beta-adrenoceptor antagonist, but is similarly potent as a membrane-stabilizer, as well as of timolol, a non-selective beta-adrenergic antagonist devoid of membrane stabilizing activity, and disopyramide, which is a membrane stabilizer, but not a beta-adrenoceptor blocker."3.71Attenuation of aortic banding-induced cardiac hypertrophy by propranolol is independent of beta-adrenoceptor blockade. ( Fadda, A; Ferrari, AU; Marano, G; Palazzesi, S; Vergari, A, 2002)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pasquale, F1
Tomé-Esteban, MT1
Morgagni, R1
Elliott, P1
Marano, G1
Palazzesi, S1
Fadda, A1
Vergari, A1
Ferrari, AU1

Other Studies

2 other studies available for disopyramide and Left Ventricular Hypertrophy

ArticleYear
Provokable left ventricular outflow tract obstruction in a patient without hypertrophy.
    Nature reviews. Cardiology, 2009, Volume: 6, Issue:4

    Topics: Angina Pectoris; Anti-Arrhythmia Agents; Atenolol; Cardiac Pacing, Artificial; Diagnostic Imaging; D

2009
Attenuation of aortic banding-induced cardiac hypertrophy by propranolol is independent of beta-adrenoceptor blockade.
    Journal of hypertension, 2002, Volume: 20, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Aorta, Abdominal; Disopyramide; Hypertrophy, Left Ventricular;

2002