disopyramide has been researched along with Infections, Respiratory in 1 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Disopyramide was metabolized by the cytochrome enzyme CYP3A4 and clarithromycin competitively inhibits this enzyme, probably resulting in an increase in plasma concentration of disopyramide." | 5.30 | Torsades de pointes ventricular tachycardia induced by clarithromycin and disopyramide in the presence of hypokalemia. ( Hashimoto, T; Hayashi, Y; Ikeda, U; Mitsuhashi, T; Shimada, K; Watanabe, T, 1999) |
| "Disopyramide was metabolized by the cytochrome enzyme CYP3A4 and clarithromycin competitively inhibits this enzyme, probably resulting in an increase in plasma concentration of disopyramide." | 1.30 | Torsades de pointes ventricular tachycardia induced by clarithromycin and disopyramide in the presence of hypokalemia. ( Hashimoto, T; Hayashi, Y; Ikeda, U; Mitsuhashi, T; Shimada, K; Watanabe, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, Y | 1 |
| Ikeda, U | 1 |
| Hashimoto, T | 1 |
| Watanabe, T | 1 |
| Mitsuhashi, T | 1 |
| Shimada, K | 1 |
1 other study available for disopyramide and Infections, Respiratory
| Article | Year |
|---|---|
Torsades de pointes ventricular tachycardia induced by clarithromycin and disopyramide in the presence of hypokalemia.
Topics: Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Arrhythmias, Cardiac; Clarithromycin; Cytochrom | 1999 |