disopyramide has been researched along with Hypotension in 17 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient is presented whose electrocardiogram became remarkably abnormal and who developed hypotension while receiving disopyramide and potassium." | 7.66 | Toxic synergism of disopyramide and hyperkalemia. ( Maddux, BD; Whiting, RB, 1980) |
| "The relative safety and efficacy of intravenous administration of adenosine, lignocaine, disopyramide, flecainide, and sotalol for termination of stable, induced ventricular tachycardia was assessed in serial trials." | 5.06 | Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia. ( Camm, AJ; Garratt, CJ; Griffith, MJ; Linker, NJ; Ward, DE, 1990) |
| "A patient is presented whose electrocardiogram became remarkably abnormal and who developed hypotension while receiving disopyramide and potassium." | 3.66 | Toxic synergism of disopyramide and hyperkalemia. ( Maddux, BD; Whiting, RB, 1980) |
| " disopyramide for a supraventricular tachycardia resulted in a more serious ventricular dysrhythmia giving hypotension and this probably contributed to the development of a myocardial infarction." | 3.66 | Adverse reaction to disopyramide. ( Dibble, JB; Webster, NR, 1979) |
| "Neurally mediated hypotension is now recognised as a common cause of otherwise unexplained recurrent syncope, but has not been reported in association with chronic fatigue." | 1.29 | Is neurally mediated hypotension an unrecognised cause of chronic fatigue? ( Bou-Holaigah, I; Calkins, H; Kan, JS; Rowe, PC, 1995) |
| "Hypotension and pulmonary edema following intravenous disopyramide is more related to the pharmacology of the drug than to the loading scheme employed." | 1.27 | Safety of multiple bolus loading of intravenous disopyramide. ( Baker, S; Benge, C; Foster, JR; Gettes, LS; Simpson, RJ, 1983) |
| "Disopyramide was administered in a bolus dose of 2 mg/kg over 10 min with an optional second bolus of 1 mg/kg and infusion of 0." | 1.26 | The antiarrhythmic effect of intravenous disopyramide in an open study. ( Bett, JH; Donnelly, GL; Heddle, WF; Kemp, RJ; Manolas, E; Nelson, GI; Sloman, JG; Tonkin, AM, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simpson, RJ | 1 |
| Foster, JR | 1 |
| Benge, C | 1 |
| Baker, S | 1 |
| Gettes, LS | 1 |
| Tonkin, AM | 1 |
| Heddle, WF | 1 |
| Bett, JH | 1 |
| Kemp, RJ | 1 |
| Donnelly, GL | 1 |
| Nelson, GI | 1 |
| Manolas, E | 1 |
| Sloman, JG | 2 |
| Drake, CE | 1 |
| Maddux, BD | 1 |
| Whiting, RB | 1 |
| Grubb, BP | 2 |
| Kosinski, D | 2 |
| Samoil, D | 1 |
| Pothoulakis, A | 2 |
| Lorton, M | 1 |
| Kip, K | 1 |
| Walden, RJ | 1 |
| Rowe, PC | 1 |
| Bou-Holaigah, I | 1 |
| Kan, JS | 1 |
| Calkins, H | 1 |
| Sneddon, JF | 1 |
| Scalia, G | 1 |
| Ward, DE | 2 |
| McKenna, WJ | 1 |
| Camm, AJ | 2 |
| Frenneaux, MP | 1 |
| Sra, JS | 1 |
| Jazayeri, MR | 1 |
| Avitall, B | 1 |
| Dhala, A | 1 |
| Deshpande, S | 1 |
| Blanck, Z | 1 |
| Akhtar, M | 1 |
| Mouhaffel, A | 1 |
| Yoshida, K | 1 |
| Kimura, K | 1 |
| Hibi, K | 1 |
| Nemoto, T | 1 |
| Iwasawa, Y | 1 |
| Hongo, Y | 1 |
| Sugiyama, M | 1 |
| Ishikawa, T | 1 |
| Kuji, N | 1 |
| Tochikubo, O | 1 |
| Ishii, M | 1 |
| Ross, D | 1 |
| Vohra, J | 2 |
| Dibble, JB | 1 |
| Webster, NR | 1 |
| Manolas, EG | 1 |
| Hunt, D | 1 |
| Dowling, JT | 1 |
| Luxton, M | 1 |
| Griffith, MJ | 1 |
| Linker, NJ | 1 |
| Garratt, CJ | 1 |
| den Dulk, K | 1 |
| Lindemans, FW | 1 |
| Brugada, P | 1 |
| Smeets, JL | 1 |
| Wellens, HJ | 1 |
| Gavaghan, TP | 1 |
| Feneley, MP | 1 |
| Campbell, TJ | 1 |
| Morgan, JJ | 1 |
1 trial available for disopyramide and Hypotension
| Article | Year |
|---|---|
Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia.
Topics: Adenosine; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Disopyramid | 1990 |
16 other studies available for disopyramide and Hypotension
| Article | Year |
|---|---|
Safety of multiple bolus loading of intravenous disopyramide.
Topics: Adult; Aged; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Female; Hemodynamics; Humans; | 1983 |
The antiarrhythmic effect of intravenous disopyramide in an open study.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Coronary Care Units; Disopyramide; Drug Evaluation; F | 1982 |
Cardiac drug overdose.
Topics: Arrhythmias, Cardiac; Bretylium Compounds; Cardiovascular Agents; Cardiovascular Diseases; Digoxin; | 1982 |
Toxic synergism of disopyramide and hyperkalemia.
Topics: Aged; Disopyramide; Drug Synergism; Electrocardiography; Humans; Hyperkalemia; Hypotension; Male; Po | 1980 |
Postpartum syncope.
Topics: 1-Naphthylamine; Administration, Oral; Adolescent; Adult; Diagnosis, Differential; Disopyramide; Dos | 1995 |
Is neurally mediated hypotension an unrecognised cause of chronic fatigue?
Topics: Atenolol; Disopyramide; Fatigue Syndrome, Chronic; Humans; Hypotension; Tilt-Table Test | 1995 |
Is neurally mediated hypotension an unrecognised cause of chronic fatigue?
Topics: Adolescent; Atenolol; Autonomic Nervous System Diseases; Blood Pressure; Child; Disopyramide; Fatigu | 1995 |
Exercise induced vasodepressor syncope.
Topics: Adolescent; Adult; Aged; Cardiac Output; Disopyramide; Exercise; Exercise Test; Female; Heart Rate; | 1994 |
Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole.
Topics: Adolescent; Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Disopyramide; Female; Follow-Up St | 1993 |
The use of methylphenidate in the treatment of refractory neurocardiogenic syncope.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Bradycardia; Central Nervous S | 1996 |
[A patient with disopyramide intoxication rescued by percutaneous cardiopulmonary support].
Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Assisted Circulation; Disopyramide; Humans; Hyp | 1998 |
Disopyramide in myocardial infarction.
Topics: Depression, Chemical; Disopyramide; Heart Block; Heart Conduction System; Humans; Hypotension; Myoca | 1978 |
Adverse reaction to disopyramide.
Topics: Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Female; Humans; Hypotension; Injections, In | 1979 |
Collapse after oral administration of disopyramide.
Topics: Abdomen; Arrhythmias, Cardiac; Disopyramide; Humans; Hypotension; Pain; Pyridines; Venous Pressure | 1979 |
Pacemaker syndrome with AAI rate variable pacing: importance of atrioventricular conduction properties, medication, and pacemaker programmability.
Topics: Aged; Atrioventricular Node; Bradycardia; Disopyramide; Dizziness; Equipment Design; Exercise; Heart | 1988 |
Atrial tachyarrhythmias after cardiac surgery: results of disopyramide therapy.
Topics: Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Digoxin; Disopyramide; Drug Therap | 1985 |