disopyramide has been researched along with Hypoglycemia in 27 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Postmarketing drug surveillance revealed the occurrence of hypoglycemia associated with the use of disopyramide phosphate (Norpace) for the control of ventricular arrhythmias." | 9.05 | Hypoglycemia in patients receiving disopyramide phosphate. ( Cohen, A; Nitzberg, DM; Schubert, EN; Strathman, I, 1983) |
| "Disopyramide, an antiarrhythmic drug, has been reported to cause hypoglycemia; however, its mechanism of action remains unclear." | 8.87 | Disopyramide-induced hypoglycemia in a non-diabetic hemodialysis patient: a case report and review of the literature. ( Abe, M; Fujii, Y; Kitai, M; Maruyama, T; Matsumoto, K; Okada, K; Soma, M, 2011) |
| " The patient had been treated with disopyramide (50 mg/day) because of paroxysmal atrial fibrillation." | 7.70 | Hypoglycemia induced by interaction between clarithromycin and disopyramide. ( Iida, H; Iwasawa, K; Morita, T; Nakajima, T; Suzuki, E; Toyo-oka, T, 1999) |
| "A case-control study was carried out to compare the risks of hypoglycemia caused by disopyramide and cibenzoline." | 7.70 | The relationship between risk of hypoglycemia and use of cibenzoline and disopyramide. ( Fujita, S; Harano, Y; Katayama, Y; Shibakawa, M; Takada, M, 2000) |
| "To report a case of disopyramide-induced hypoglycemia and to discuss the observed inadequate adrenergic response in this patient." | 7.68 | Inadequate adrenergic response to disopyramide-induced hypoglycemia. ( Geller, J; Smith, RC; Sullivan, M, 1992) |
| "In a 41-year-old male with diabetes mellitus well controlled with insulin (50 units/day), hypoglycemia developed after starting disopyramide treatment (200 mg/day) for correction of tachycardia." | 7.66 | Hypoglycemic effect of disopyramide in a case of diabetes mellitus under insulin treatment. ( Taketa, K; Yamamoto, Y, 1980) |
| "Disopyramide is a group I antiarrhythmic drug which is mainly used for the treatment of ventricular and supraventricular rhythm disturbances." | 5.28 | Disopyramide-induced hypoglycemia: case report and review of the literature. ( Baumelou, A; Cacoub, P; Deray, G; Grimaldi, A; Jacobs, C; Soubrie, C, 1989) |
| "Disopyramide (Norpace) is a widely used, generally well tolerated antiarrhythmic agent." | 5.27 | Hypoglycemic coma due to disopyramide toxicity. ( Gillman, MW; Stapleton, JT, 1983) |
| "Disopyramide (Norpace) is a recently released antiarrhythmic agent with quinidine-like actions, but structurally unique." | 5.26 | Disopyramide (Norpace)-induced hypoglycemia. ( Brown, LK; Goldberg, IJ; Rayfield, EJ, 1980) |
| "Postmarketing drug surveillance revealed the occurrence of hypoglycemia associated with the use of disopyramide phosphate (Norpace) for the control of ventricular arrhythmias." | 5.05 | Hypoglycemia in patients receiving disopyramide phosphate. ( Cohen, A; Nitzberg, DM; Schubert, EN; Strathman, I, 1983) |
| "Disopyramide, an antiarrhythmic drug, has been reported to cause hypoglycemia; however, its mechanism of action remains unclear." | 4.87 | Disopyramide-induced hypoglycemia in a non-diabetic hemodialysis patient: a case report and review of the literature. ( Abe, M; Fujii, Y; Kitai, M; Maruyama, T; Matsumoto, K; Okada, K; Soma, M, 2011) |
| "Disopyramide, an antiarrhythmia drug, has been reported to cause hypoglycaemia." | 3.75 | Mechanism of disopyramide-induced hypoglycaemia in a patient with Type 2 diabetes. ( Mori, M; Negishi, M; Proks, P; Shimomura, K; Shimomura, Y, 2009) |
| "Cases of severe cardiac arrhythmia and major hypoglycaemia have occurred in patients receiving disopyramide simultaneously with some macrolide antibiotics, especially erythromycin and clarithromycin." | 3.71 | Disopyramide: interactions with marcolide antibiotics. ( , 2001) |
| " The patient had been treated with disopyramide (50 mg/day) because of paroxysmal atrial fibrillation." | 3.70 | Hypoglycemia induced by interaction between clarithromycin and disopyramide. ( Iida, H; Iwasawa, K; Morita, T; Nakajima, T; Suzuki, E; Toyo-oka, T, 1999) |
| "A case-control study was carried out to compare the risks of hypoglycemia caused by disopyramide and cibenzoline." | 3.70 | The relationship between risk of hypoglycemia and use of cibenzoline and disopyramide. ( Fujita, S; Harano, Y; Katayama, Y; Shibakawa, M; Takada, M, 2000) |
| "Twenty-nine cases of hypoglycemia induced by disopyramide (DP) have been reported in the literature to date." | 3.68 | [Accumulation of a disopyramide metabolite in renal failure]. ( Amano, I; Inagaki, Y; Ito, T; Masamoto, S; Niwa, M; Otsu, T, 1993) |
| "To report a case of disopyramide-induced hypoglycemia and to discuss the observed inadequate adrenergic response in this patient." | 3.68 | Inadequate adrenergic response to disopyramide-induced hypoglycemia. ( Geller, J; Smith, RC; Sullivan, M, 1992) |
| "In a 41-year-old male with diabetes mellitus well controlled with insulin (50 units/day), hypoglycemia developed after starting disopyramide treatment (200 mg/day) for correction of tachycardia." | 3.66 | Hypoglycemic effect of disopyramide in a case of diabetes mellitus under insulin treatment. ( Taketa, K; Yamamoto, Y, 1980) |
| "Disopyramide is a group I antiarrhythmic drug which is mainly used for the treatment of ventricular and supraventricular rhythm disturbances." | 1.28 | Disopyramide-induced hypoglycemia: case report and review of the literature. ( Baumelou, A; Cacoub, P; Deray, G; Grimaldi, A; Jacobs, C; Soubrie, C, 1989) |
| "Disopyramide (Norpace) is a widely used, generally well tolerated antiarrhythmic agent." | 1.27 | Hypoglycemic coma due to disopyramide toxicity. ( Gillman, MW; Stapleton, JT, 1983) |
| "Disopyramide (Norpace) is a recently released antiarrhythmic agent with quinidine-like actions, but structurally unique." | 1.26 | Disopyramide (Norpace)-induced hypoglycemia. ( Brown, LK; Goldberg, IJ; Rayfield, EJ, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (59.26) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Negishi, M | 1 |
| Shimomura, K | 1 |
| Proks, P | 1 |
| Mori, M | 1 |
| Shimomura, Y | 1 |
| Abe, M | 1 |
| Maruyama, T | 1 |
| Fujii, Y | 1 |
| Kitai, M | 1 |
| Okada, K | 1 |
| Matsumoto, K | 1 |
| Soma, M | 1 |
| Semel, JD | 1 |
| Wortham, E | 1 |
| Karl, DM | 1 |
| Nappi, JM | 1 |
| Dhanani, S | 1 |
| Lovejoy, JR | 1 |
| VanderArk, C | 1 |
| Strathman, I | 1 |
| Schubert, EN | 1 |
| Cohen, A | 1 |
| Nitzberg, DM | 1 |
| Taketa, K | 1 |
| Yamamoto, Y | 1 |
| Stapleton, JT | 1 |
| Gillman, MW | 1 |
| Ohnishi, K | 1 |
| Akiba, T | 1 |
| Miyake, S | 1 |
| Ajisaka, R | 1 |
| Quevedo, SF | 1 |
| Krauss, DS | 1 |
| Chazan, JA | 1 |
| Crisafulli, FS | 1 |
| Kahn, CB | 1 |
| Hartigan, JD | 1 |
| Goldberg, IJ | 1 |
| Brown, LK | 1 |
| Rayfield, EJ | 1 |
| Chaussade, S | 1 |
| Beucler, A | 1 |
| Lafaix, C | 1 |
| Hadjadj, S | 1 |
| Duquenne, M | 1 |
| Duriez, T | 1 |
| Hanesse, B | 1 |
| Weryha, G | 1 |
| Leclère, J | 1 |
| Otsu, T | 1 |
| Ito, T | 1 |
| Inagaki, Y | 1 |
| Amano, I | 1 |
| Masamoto, S | 1 |
| Niwa, M | 1 |
| Iida, H | 1 |
| Morita, T | 1 |
| Suzuki, E | 1 |
| Iwasawa, K | 1 |
| Toyo-oka, T | 1 |
| Nakajima, T | 1 |
| Takada, M | 1 |
| Fujita, S | 1 |
| Katayama, Y | 1 |
| Harano, Y | 1 |
| Shibakawa, M | 1 |
| Reynolds, RM | 1 |
| Walker, JD | 1 |
| Smith, RC | 1 |
| Sullivan, M | 1 |
| Geller, J | 1 |
| Alvarsson, M | 1 |
| Grill, V | 1 |
| Hamberger, B | 1 |
| Grimelius, L | 1 |
| Turtzo, DF | 1 |
| Ghatak, PK | 1 |
| Naitoh, M | 1 |
| Tominaga, T | 1 |
| Suzuki, H | 1 |
| Saruta, T | 1 |
| Deguchi, N | 1 |
| Cacoub, P | 2 |
| Deray, G | 2 |
| Baumelou, A | 2 |
| Grimaldi, A | 2 |
| Soubrie, C | 2 |
| Jacobs, C | 2 |
| Croxson, MS | 1 |
| Shaw, DW | 1 |
| Henley, PG | 1 |
| Gabriel, HD | 1 |
| Mitamura, H | 1 |
4 reviews available for disopyramide and Hypoglycemia
| Article | Year |
|---|---|
Disopyramide-induced hypoglycemia in a non-diabetic hemodialysis patient: a case report and review of the literature.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Female; Humans; Hypoglycemia; Polyp | 2011 |
[Hypoglycemia caused by disopyramide: physiopathology].
Topics: Aged; Aged, 80 and over; Disopyramide; Female; Humans; Hypoglycemia | 1995 |
[Antiarrhythmic agent caused marked hypoglycemia in a patient receiving hemodialysis: relation with disopyramide and verapamil].
Topics: Aged; Blood Glucose; Cardiac Complexes, Premature; Disopyramide; Drug Therapy, Combination; Glucose | 1988 |
Disopyramide-induced hypoglycaemia and increased serum insulin.
Topics: Aged; Disopyramide; Humans; Hypoglycemia; Insulin; Male; Stimulation, Chemical | 1987 |
1 trial available for disopyramide and Hypoglycemia
| Article | Year |
|---|---|
Hypoglycemia in patients receiving disopyramide phosphate.
Topics: Aged; Blood Glucose; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Disopyramide; | 1983 |
22 other studies available for disopyramide and Hypoglycemia
| Article | Year |
|---|---|
Mechanism of disopyramide-induced hypoglycaemia in a patient with Type 2 diabetes.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Ang | 2009 |
Drug-induced hypoglycaemia.
Topics: Anti-Bacterial Agents; Blood Glucose; Carbamates; Dextropropoxyphene; Diabetes Mellitus; Disopyramid | 2009 |
Fasting hypoglycemia associated with disopyramide.
Topics: Aged; Arrhythmias, Cardiac; Disopyramide; Humans; Hypoglycemia; Insulin; Male | 1983 |
Severe hypoglycemia associated with disopyramide.
Topics: Aged; Arrhythmias, Cardiac; Disopyramide; Humans; Hypoglycemia; Male; Pyridines | 1983 |
Hypoglycemic effect of disopyramide in a case of diabetes mellitus under insulin treatment.
Topics: Adult; Diabetes Complications; Diabetes Mellitus; Disopyramide; Humans; Hypoglycemia; Insulin; Male; | 1980 |
Hypoglycemic coma due to disopyramide toxicity.
Topics: Aged; Coma; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disopyramide; Humans; Hypoglycemia; M | 1983 |
[Case of disopyramide-induced hypoglycemia].
Topics: Aged; Arrhythmias, Cardiac; Disopyramide; Humans; Hypoglycemia; Male | 1983 |
Fasting hypoglycemia secondary to disopyramide therapy. Report of two cases.
Topics: Aged; Arrhythmias, Cardiac; Blood Glucose; Disopyramide; Fasting; Female; Humans; Hypoglycemia; Male | 1981 |
Severe hypoglycemia complicating disopyramide (Norpace) therapy. A case report.
Topics: Aged; Disopyramide; Female; Humans; Hypoglycemia; Nutrition Disorders; Pneumonia; Pyridines | 1983 |
Disopyramide (Norpace)-induced hypoglycemia.
Topics: Aged; Alanine; Atrial Flutter; Disopyramide; Female; Glucagon; Gluconeogenesis; Glucose Tolerance Te | 1980 |
[Hypoglycemia induced by disopyramide. Case report].
Topics: Aged; Disopyramide; Female; Humans; Hypoglycemia; Pyridines | 1982 |
[Accumulation of a disopyramide metabolite in renal failure].
Topics: Adult; Aged; Aged, 80 and over; Disopyramide; Female; Humans; Hypoglycemia; Kidney Failure, Chronic; | 1993 |
Hypoglycemia induced by interaction between clarithromycin and disopyramide.
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Atrial Fibrillation; Clarithromycin; Disopyramide; Dr | 1999 |
The relationship between risk of hypoglycemia and use of cibenzoline and disopyramide.
Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Blood Glucose; Case-Control Studies; Disopyr | 2000 |
Disopyramide: interactions with marcolide antibiotics.
Topics: Anti-Arrhythmia Agents; Anti-Bacterial Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Disop | 2001 |
Hypoglycaemia induced by disopyramide in a patient with Type 2 diabetes mellitus.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Diabetes Mellitus, Type 2; Disopyramide; Drug The | 2001 |
Inadequate adrenergic response to disopyramide-induced hypoglycemia.
Topics: Aged; C-Peptide; Disopyramide; Humans; Hypoglycemia; Insulin; Male | 1992 |
[Intake of disopyramide led to diagnosis of insulinoma].
Topics: Aged; Disopyramide; Female; Humans; Hypoglycemia; Insulinoma; Pancreatic Neoplasms | 1991 |
Disopyramide induced hypoglycemia.
Topics: Aged; Cardiac Complexes, Premature; Disopyramide; Humans; Hypoglycemia; Male | 1986 |
Disopyramide-induced hypoglycemia: case report and review of the literature.
Topics: Aged; Blood Glucose; C-Peptide; Disopyramide; Humans; Hypoglycemia; Insulin; Kidney Failure, Chronic | 1989 |
[Severe hypoglycemia induced by disopyramide].
Topics: Aged; Disopyramide; Humans; Hypoglycemia; Male | 1988 |
[A study on disopyramide-induced hypoglycemia].
Topics: Animals; Blood Glucose; Disopyramide; Hypoglycemia; Insulin; Male; Rats; Rats, Inbred Strains | 1985 |