disopyramide has been researched along with Diarrhea in 3 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Searle), literature demonstrating its efficacy in maintaining uniform serum drug levels over a 12-h dosing interval is derived from only normal healthy volunteers." | 1.27 | Serum drug concentrations and adverse effects in cardiac patients after administration of a new controlled-release disopyramide preparation. ( Zema, MJ, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schimpf, R | 1 |
| Veltmann, C | 1 |
| Giustetto, C | 1 |
| Gaita, F | 1 |
| Borggrefe, M | 1 |
| Wolpert, C | 1 |
| Zema, MJ | 1 |
| Oshrain, C | 1 |
1 trial available for disopyramide and Diarrhea
| Article | Year |
|---|---|
Clinical studies of Norpace (Part IX).
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Diarrhea; Disopyramide; Drug | 1975 |
2 other studies available for disopyramide and Diarrhea
| Article | Year |
|---|---|
In vivo effects of mutant HERG K+ channel inhibition by disopyramide in patients with a short QT-1 syndrome: a pilot study.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diarrhea; Disopyramide; ERG1 Potassium Ch | 2007 |
Serum drug concentrations and adverse effects in cardiac patients after administration of a new controlled-release disopyramide preparation.
Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Delayed-Action Preparations; Diarrhea; Diso | 1984 |