disopyramide has been researched along with Death, Sudden, Cardiac in 7 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Drug treatment of hypertrophic cardiomyopathy is the first-line treatment, at the onset of clinical signs and symptoms." | 1.35 | [Drug treatment for hypertrophic cardiomyopathy]. ( Gibelin, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Rowin, EJ | 1 |
| Sridharan, A | 1 |
| Madias, C | 1 |
| Firely, C | 1 |
| Koethe, B | 1 |
| Link, MS | 1 |
| Maron, MS | 1 |
| Maron, BJ | 2 |
| Hamada, M | 1 |
| Ikeda, S | 1 |
| Shigematsu, Y | 1 |
| Gibelin, P | 1 |
| Sherrid, MV | 1 |
| Barac, I | 1 |
| McKenna, WJ | 1 |
| Elliott, PM | 1 |
| Dickie, S | 1 |
| Chojnowska, L | 1 |
| Casey, S | 1 |
| McPate, MJ | 1 |
| Duncan, RS | 1 |
| Witchel, HJ | 1 |
| Hancox, JC | 1 |
| Dumaine, R | 1 |
| Antzelevitch, C | 1 |
| Miyanuma, H | 1 |
| Sakurai, M | 1 |
| Odaka, H | 1 |
| Yamazaki, T | 1 |
| Mitobe, H | 1 |
| Muraguti, I | 1 |
| Iwama, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy-- a Multicenter Randomized Control Trial[NCT02948998] | Phase 4 | 260 participants (Anticipated) | Interventional | 2018-05-14 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for disopyramide and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Advances in medical treatment of hypertrophic cardiomyopathy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Calcium Channel Blocke | 2014 |
6 other studies available for disopyramide and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Prediction and Prevention of Sudden Death in Young Patients (<20 years) With Hypertrophic Cardiomyopathy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Ca | 2020 |
[Drug treatment for hypertrophic cardiomyopathy].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiomyop | 2009 |
Multicenter study of the efficacy and safety of disopyramide in obstructive hypertrophic cardiomyopathy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrop | 2005 |
Disopyramide is an effective inhibitor of mutant HERG K+ channels involved in variant 1 short QT syndrome.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; CHO Cells; Cricetinae; Cricetulus; Death, Sud | 2006 |
Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome?
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Disopyramide; Drug Interaction | 2006 |
[Two cases of idiopathic ventricular fibrillation with interesting electrocardiographic findings].
Topics: Adult; Death, Sudden, Cardiac; Disopyramide; Electric Stimulation; Electrocardiography; Humans; Male | 1993 |