Page last updated: 2024-10-26

disopyramide and Cirrhosis, Liver

disopyramide has been researched along with Cirrhosis, Liver in 4 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Research Excerpts

ExcerptRelevanceReference
"The plasma protein binding of disopyramide (D) was determined in seven patients with cirrhosis, six with nephrotic syndrome, and seven healthy subjects."7.67Protein binding of disopyramide in liver cirrhosis and in nephrotic syndrome. ( Echizen, H; Ishizaki, T; Saima, S; Umeda, N, 1986)
"The plasma protein binding of disopyramide (D) was determined in seven patients with cirrhosis, six with nephrotic syndrome, and seven healthy subjects."3.67Protein binding of disopyramide in liver cirrhosis and in nephrotic syndrome. ( Echizen, H; Ishizaki, T; Saima, S; Umeda, N, 1986)
" The clinical implication of the present findings appear to be that the dosage of disopyramide should be reduced by 25% when it is given intravenously to patients with decreased hepatic function."1.27Kinetics of disopyramide in decreased hepatic function. ( Angelo, HR; Balsløv, S; Bonde, J; Graudal, NA; Kampmann, JP; Pedersen, LE; Svendsen, TL, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belpaire, FM1
Bogaert, MG1
Echizen, H1
Saima, S1
Umeda, N1
Ishizaki, T1
Bonde, J2
Graudal, NA2
Pedersen, LE2
Balsløv, S1
Angelo, HR1
Svendsen, TL1
Kampmann, JP2
Backer, NV1
Hansen, JE1

Other Studies

4 other studies available for disopyramide and Cirrhosis, Liver

ArticleYear
Binding of alfentanil to human alpha 1-acid glycoprotein, albumin and serum.
    International journal of clinical pharmacology, therapy, and toxicology, 1991, Volume: 29, Issue:3

    Topics: Adult; Aged; Alfentanil; Arthritis, Rheumatoid; Disopyramide; Female; Humans; Kidney Failure, Chroni

1991
Protein binding of disopyramide in liver cirrhosis and in nephrotic syndrome.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Blood Proteins; Disopyramide; Female; Fluorescence Polarization;

1986
Kinetics of disopyramide in decreased hepatic function.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:1

    Topics: Adult; Aged; Disopyramide; Female; Half-Life; Humans; Kinetics; Liver Cirrhosis; Liver Function Test

1986
Quantitative and qualitative binding characteristics of disopyramide in serum from patients with decreased renal and hepatic function.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:1

    Topics: Adult; Aged; Coronary Disease; Disopyramide; Female; Humans; Kidney Failure, Chronic; Liver Cirrhosi

1987