disopyramide has been researched along with Chronic Disease in 17 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Safety and efficacy of propafenone and disopyramide for long-term maintenance of sinus rhythm after electrical cardioversion was studied in 56 patients with chronic atrial fibrillation (median arrhythmia duration, 5 months)." | 9.08 | Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group. ( Crijns, HJ; Gosselink, AT; Lie, KI, 1996) |
| "The efficacy of disopyramide compared to placebo for exercise induced ventricular arrhythmias was tested in a double-blind randomized controlled clinical trial with cross-over design in 14 patients with coronary heart disease." | 9.06 | Efficacy of and adverse effects of disopyramide. Comparison of capsules, controlled release tablets and placebo in patients with chronic ventricular arrhythmias. ( Ekelund, LG; Nilsson, E; Walldius, G, 1986) |
| " The high incidence of side-effects was probably due to the high dosage used." | 6.65 | Evaluation of the antiarrhythmic efficacy of mexiletine in patients with chronic ventricular arrhythmias. ( Van Durme, JP, 1980) |
| "Safety and efficacy of propafenone and disopyramide for long-term maintenance of sinus rhythm after electrical cardioversion was studied in 56 patients with chronic atrial fibrillation (median arrhythmia duration, 5 months)." | 5.08 | Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group. ( Crijns, HJ; Gosselink, AT; Lie, KI, 1996) |
| "The efficacy of disopyramide compared to placebo for exercise induced ventricular arrhythmias was tested in a double-blind randomized controlled clinical trial with cross-over design in 14 patients with coronary heart disease." | 5.06 | Efficacy of and adverse effects of disopyramide. Comparison of capsules, controlled release tablets and placebo in patients with chronic ventricular arrhythmias. ( Ekelund, LG; Nilsson, E; Walldius, G, 1986) |
| "The efficacy of disopyramide (DP), mexiletine (MX), aprindine (AP) and cibenzoline (CZ) on ventricular arrhythmias was compared (single drug therapy)." | 3.67 | Therapeutic effectiveness and plasma levels of single or combination use of class I antiarrhythmic agents for ventricular arrhythmias. ( Furuya, H; Goto, Y; Tanabe, T; Yoshikawa, H, 1988) |
| " The high incidence of side-effects was probably due to the high dosage used." | 2.65 | Evaluation of the antiarrhythmic efficacy of mexiletine in patients with chronic ventricular arrhythmias. ( Van Durme, JP, 1980) |
| "Each cough was preceded by a premature beat." | 1.33 | Cough reflex by ventricular premature contractions. ( Fujita, M; Kihara, Y; Niimi, A; Okano, Y; Sumita, Y; Tambara, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (70.59) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takada, Y | 1 |
| Isobe, S | 1 |
| Okada, M | 1 |
| Ando, A | 1 |
| Nonokawa, M | 1 |
| Inden, Y | 1 |
| Tomita, Y | 1 |
| Suzuki, A | 1 |
| Hirai, M | 1 |
| Murohara, T | 1 |
| Niimi, A | 1 |
| Kihara, Y | 1 |
| Sumita, Y | 1 |
| Okano, Y | 1 |
| Tambara, K | 1 |
| Fujita, M | 1 |
| Garson, A | 1 |
| Gillette, PC | 1 |
| Chimienti, M | 1 |
| Panciroli, C | 1 |
| Salerno, JA | 1 |
| Regazzi-Bonora, M | 1 |
| Previtali, M | 1 |
| Cristiani, D | 1 |
| Rondanelli, R | 1 |
| Bobba, P | 1 |
| Van Durme, JP | 1 |
| Naccarella, F | 1 |
| Palmieri, M | 1 |
| del Corso, P | 1 |
| Lombardi, G | 1 |
| Bracchetti, D | 1 |
| Crijns, HJ | 1 |
| Gosselink, AT | 1 |
| Lie, KI | 1 |
| Kumagai, K | 1 |
| Yamanouchi, Y | 1 |
| Hiroki, T | 1 |
| Arakawa, K | 1 |
| Grosu, AA | 1 |
| Shevchenko, NM | 1 |
| Libersa, C | 1 |
| Caron, J | 1 |
| Pladys, A | 1 |
| Beuscart, R | 1 |
| Kacet, S | 1 |
| Wajman, A | 1 |
| Connell, C | 1 |
| Dupuis, B | 1 |
| Lekieffre, J | 1 |
| Della Bella, P | 1 |
| Marenzi, G | 1 |
| Doni, F | 1 |
| Tondo, C | 1 |
| Cipolla, C | 1 |
| Grazi, S | 1 |
| Rimondini, A | 1 |
| Salvioni, A | 1 |
| Guazzi, MD | 1 |
| Priori, SG | 1 |
| Bonazzi, O | 1 |
| Facchini, M | 1 |
| Varisco, T | 1 |
| Schwartz, PJ | 1 |
| Jonason, T | 1 |
| Ringqvist, I | 1 |
| Bandh, S | 1 |
| Nilsson, G | 1 |
| Nilsson, H | 1 |
| Lidell, C | 1 |
| Bjerle, P | 1 |
| Olofsson, BO | 1 |
| Lundström, T | 1 |
| Rydén, L | 1 |
| Tanabe, T | 1 |
| Yoshikawa, H | 1 |
| Furuya, H | 1 |
| Goto, Y | 1 |
| Ekelund, LG | 1 |
| Nilsson, E | 1 |
| Walldius, G | 1 |
| Nakazawa, HK | 1 |
| Handa, S | 1 |
| Nakamura, Y | 1 |
| Oyanagi, H | 1 |
| Hasegawa, M | 1 |
| Ishikawa, N | 1 |
| Ozaki, O | 1 |
| Ito, K | 1 |
8 trials available for disopyramide and Chronic Disease
| Article | Year |
|---|---|
Effects of antiarrhythmic agents on left ventricular function during exercise in patients with chronic left ventricular dysfunction.
Topics: Aged; Anti-Asthmatic Agents; Chronic Disease; Disopyramide; Exercise; Exercise Test; Female; Heart V | 2004 |
Dihydroquinidine versus disopyramide: efficacy in patients with chronic stable ventricular ectopy.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Disopyrami | 1984 |
Evaluation of the antiarrhythmic efficacy of mexiletine in patients with chronic ventricular arrhythmias.
Topics: Arrhythmias, Cardiac; Atenolol; Chronic Disease; Clinical Trials as Topic; Disopyramide; Double-Blin | 1980 |
Comparison of the efficacy of propafenone versus disopyramide for complex premature ventricular contractions. Evaluation with long-term monitoring.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Disopyramide | 1982 |
Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Disopyramide; Do | 1996 |
Propafenone versus disopyramide: a double-blind randomized crossover trial in patients presenting chronic ventricular arrhythmias.
Topics: Adult; Aged; Cardiac Complexes, Premature; Chronic Disease; Disopyramide; Double-Blind Method; Femal | 1987 |
Propafenone versus disopyramide for treatment of chronic symptomatic ventricular arrhythmias. A multicenter study.
Topics: Adult; Aged; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Disopyramide; Electroc | 1988 |
Efficacy of and adverse effects of disopyramide. Comparison of capsules, controlled release tablets and placebo in patients with chronic ventricular arrhythmias.
Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Capsules; Chronic Disease; Clinical Trials as Topic; Del | 1986 |
9 other studies available for disopyramide and Chronic Disease
| Article | Year |
|---|---|
Cough reflex by ventricular premature contractions.
Topics: Anti-Arrhythmia Agents; Chronic Disease; Cough; Disopyramide; Echocardiography, Doppler; Electrocard | 2005 |
Treatment of chronic ventricular dysrhythmias in the young.
Topics: Administration, Oral; Adolescent; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Child, | 1981 |
Effects of transcatheter cardioversion on chronic lone atrial fibrillation.
Topics: Atrial Fibrillation; Cardiac Catheterization; Cardiac Pacing, Artificial; Chronic Disease; Disopyram | 1991 |
[The potentials for curing atrial flutter by the combined use of transesophageal electrical stimulation and anti-arrhythmia preparations].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificial; Chronic Disease; Co | 1990 |
[Efficacy of disopyramide in the treatment of atrial flutter with overdrive pacing].
Topics: Aged; Atrial Flutter; Cardiac Pacing, Artificial; Chronic Disease; Disopyramide; Electrocardiography | 1989 |
Antiarrhythmic efficacy of penticainide and comparison with disopyramide, flecainide, propafenone and mexiletine by acute oral drug testing.
Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Di | 1987 |
Chronic atrial fibrillation. Long-term results of direct current conversion.
Topics: Adult; Aged; Atrial Fibrillation; Chronic Disease; Disopyramide; Electric Countershock; Female; Foll | 1988 |
Therapeutic effectiveness and plasma levels of single or combination use of class I antiarrhythmic agents for ventricular arrhythmias.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Chronic Disease; Disopyramide; | 1988 |
High maintenance rate of sinus rhythm after cardioversion in post-thyrotoxic chronic atrial fibrillation.
Topics: Adult; Atrial Fibrillation; Chronic Disease; Disopyramide; Electric Countershock; Electrocardiograph | 1987 |