disopyramide has been researched along with Chagas Cardiomyopathy in 2 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Low-dose (7 mg/kg per day) disopyramide administration to arrhythmic chagasic patients decreased the frequency of ventricular extrasystoles in 4 of 17 patients (24%) and suppressed most complex ventricular arrhythmias in 12 of 15 patients (80%)." | 9.05 | Effect of low oral doses of disopyramide and amiodarone on ventricular and atrial arrhythmias of chagasic patients with advanced myocardial damage. ( Carrasco, HA; Fuenmayor, A; Landaeta, A; López, F; Molina, C; Reynosa, J; Vicuña, AV; Vicuña, N, 1985) |
| "Low-dose (7 mg/kg per day) disopyramide administration to arrhythmic chagasic patients decreased the frequency of ventricular extrasystoles in 4 of 17 patients (24%) and suppressed most complex ventricular arrhythmias in 12 of 15 patients (80%)." | 5.05 | Effect of low oral doses of disopyramide and amiodarone on ventricular and atrial arrhythmias of chagasic patients with advanced myocardial damage. ( Carrasco, HA; Fuenmayor, A; Landaeta, A; López, F; Molina, C; Reynosa, J; Vicuña, AV; Vicuña, N, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pimenta, J | 1 |
| Pereira, CB | 1 |
| Carrasco, HA | 1 |
| Vicuña, AV | 1 |
| Molina, C | 1 |
| Landaeta, A | 1 |
| Reynosa, J | 1 |
| Vicuña, N | 1 |
| Fuenmayor, A | 1 |
| López, F | 1 |
1 trial available for disopyramide and Chagas Cardiomyopathy
| Article | Year |
|---|---|
Effect of low oral doses of disopyramide and amiodarone on ventricular and atrial arrhythmias of chagasic patients with advanced myocardial damage.
Topics: Administration, Oral; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chagas Cardiomyopa | 1985 |
1 other study available for disopyramide and Chagas Cardiomyopathy
| Article | Year |
|---|---|
Electrophysiologic effects of disopyramide in Chagas' disease with bundle branch block.
Topics: Adult; Bundle-Branch Block; Chagas Cardiomyopathy; Disopyramide; Heart Conduction System; Humans | 1984 |