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disopyramide and Cardiomyopathy, Hypertrophic Obstructive

disopyramide has been researched along with Cardiomyopathy, Hypertrophic Obstructive in 52 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Research Excerpts

ExcerptRelevanceReference
"Disopyramide as an antiarrhythmic can be prescribed to patients with atrial fibrillation and, owing to its negative inotropic effect, to patients with hypertrophic obstructive cardiomyopathy."3.69Heart conduction disturbances and cardiovascular collapse after disopyramide and low-dose metoprolol in a patient with hypertrophic obstructive cardiomyopathy. ( Horvat, M; Pernat, A; Pohar, B, 1997)
"Disopyramide was more effective than propranolol (p less than 0."2.66Disopyramide in hypertrophic cardiomyopathy. II. Noninvasive assessment after oral administration. ( Pollick, C, 1988)
"Hypertrophic cardiomyopathy is a heterogenous condition associated with a myriad of symptoms."2.61Lifestyle Modification and Medical Management of Hypertrophic Cardiomyopathy. ( Fischer, KL; Heitner, SB, 2019)
" This combination allows adequate dosing of disopyramide to achieve therapeutic goals."2.53Drug Therapy for Hypertrophic Cardiomypathy: Physiology and Practice. ( Sherrid, MV, 2016)
"Disopyramide is a class Ia antiarrhythmic that historically was used for the treatment of arrhythmias; however, its contemporary use is often reserved for patients with HCM who are persistently symptomatic despite β-blockers or verapamil and have evidence of LVOT obstruction."2.52Disopyramide for Hypertrophic Cardiomyopathy: A Pragmatic Reappraisal of an Old Drug. ( Coons, JC; Verlinden, NJ, 2015)
"Physicians treating hypertrophic cardiomyopathy (HCM) are faced with unique management challenges."2.43Pathophysiology of hypertrophic cardiomyopathy determines its medical treatment. ( Musat, D; Sherrid, MV, 2006)
"Disopyramide is a safe and effective treatment for LVOTO-related symptoms in childhood obstructive HCM."1.91Disopyramide is a safe and effective treatment for children with obstructive hypertrophic cardiomyopathy. ( Boleti, O; Cervi, E; Field, E; Kaski, JP; Norrish, G; Topriceanu, CC, 2023)
"Treatment with bisoprolol was well-tolerated and effective in relieving obstruction and improving symptoms in a significant proportion of patients with symptomatic obstructive HCM."1.72Bisoprolol for treatment of symptomatic patients with obstructive hypertrophic cardiomyopathy. The BASIC (bisoprolol AS therapy in hypertrophic cardiomyopathy) study. ( Caiazza, M; Calabrò, P; Cirillo, A; Dongiglio, F; Franco, F; Fusco, A; Limongelli, G; Lioncino, M; Mazzella, M; Monda, E; Moscarella, E; Pacileo, G; Palmiero, G; Rubino, M; Sepe, J; Verrillo, F, 2022)
"Disopyramide is a sodium channel blocker with negative inotropic properties that effectively reduces left ventricular outflow tract gradients in adults with hypertrophic cardiomyopathy, but its efficacy in children is uncertain."1.48Disopyramide use in infants and children with hypertrophic cardiomyopathy. ( Hanna, BD; Lin, KY; Miller, K; O'Connor, MJ; Ravishankar, C; Rossano, JW; Shaddy, RE, 2018)
"Initiation of disopyramide in the outpatient setting is safe and the risk of subsequent sudden cardiac death is low."1.46Safety of Outpatient Initiation of Disopyramide for Obstructive Hypertrophic Cardiomyopathy Patients. ( Adler, A; Chan, RH; Fourey, D; Gollob, MH; Hindieh, W; Rakowski, H; Weissler-Snir, A, 2017)
"Disopyramide was added in 221 (74%) patients and pharmacological control of symptoms was achieved in 141 (64%) patients."1.39Treatment of obstructive hypertrophic cardiomyopathy symptoms and gradient resistant to first-line therapy with β-blockade or verapamil. ( Alviar, CL; Balaram, SK; Homel, P; Kim, B; Musat, D; Sherrid, MV; Shetty, A; Swistel, DG; Winson, G, 2013)
"Drug treatment of hypertrophic cardiomyopathy is the first-line treatment, at the onset of clinical signs and symptoms."1.35[Drug treatment for hypertrophic cardiomyopathy]. ( Gibelin, P, 2009)
"When severe COPD and obstructive hypertrophic cardiomyopathy (HCM) coexist, management is challenging and complex."1.35Oral disopyramide for the acute treatment of severe outflow obstruction in hypertrophic cardiomyopathy in the ICU setting. ( Sherrid, MV; Sirak, TE, 2008)
" Acute and long-term administration of propranolol lead to a significant reduction in heart rate at rest and during exercise."1.28Effect of propranolol and disopyramide on left ventricular function at rest and during exercise in hypertrophic cardiomyopathy. ( Hartmann, A; Hopf, R; Hör, G; Kaltenbach, M; Klepzig, H; Kober, G; Kühn, J; Maul, FD; Standke, R, 1992)
" However, the lower, sustained dosage of disopyramide was associated with a lower average serum level of 2."1.27Effects of disopyramide on left ventricular function: assessment by radionuclide cineangiography. ( Bates, R; Dibianco, R; Fletcher, RD; Gottdiener, JS; Sauerbrunn, BJ, 1983)
"Thus disopyramide, probably because of its negative inotropic action, is useful in the management of patients with HCM when LV outflow obstruction is the main cause of the clinical-hemodynamic findings."1.27[Beneficial effects of disopyramide on left ventricular outflow obstruction in a case of hypertrophic obstructive cardiomyopathy]. ( Contini, GM; Dore, L; Franceschino, V; Ibba, GV; Terrosu, P, 1984)
"Disopyramide serum levels were measured at the time of echocardiography."1.27Oral disopyramide therapy for obstructive hypertrophic cardiomyopathy. ( Delia, E; Dwyer, E; Sherrid, M, 1988)

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19908 (15.38)18.7374
1990's19 (36.54)18.2507
2000's7 (13.46)29.6817
2010's12 (23.08)24.3611
2020's6 (11.54)2.80

Authors

AuthorsStudies
Monda, E1
Lioncino, M1
Palmiero, G1
Franco, F1
Rubino, M1
Cirillo, A1
Verrillo, F1
Fusco, A1
Caiazza, M1
Mazzella, M1
Moscarella, E1
Dongiglio, F1
Sepe, J1
Pacileo, G1
Calabrò, P1
Limongelli, G1
Topriceanu, CC1
Field, E1
Boleti, O1
Cervi, E1
Kaski, JP1
Norrish, G1
Owens, AT1
Masri, A1
Abraham, TP1
Choudhury, L1
Rader, F1
Symanski, JD1
Turer, AT1
Wong, TC1
Tower-Rader, A1
Coats, CJ1
Fifer, MA2
Olivotto, I1
Solomon, SD1
Watkins, HC1
Heitner, SB2
Jacoby, DL1
Kupfer, S1
Malik, FI1
Meng, L1
Sohn, R1
Wohltman, A1
Maron, MS2
Hori, Y1
Fujimoto, E1
Nishikawa, Y1
Nakamura, T1
Rodriguez-Gonzalez, M1
Pérez-Reviriego, ÁA1
Castellano-Martinez, A1
Cascales-Poyatos, HM1
Rowin, EJ1
Sridharan, A1
Madias, C1
Firely, C1
Koethe, B1
Link, MS1
Maron, BJ2
Adler, A1
Fourey, D1
Weissler-Snir, A1
Hindieh, W1
Chan, RH1
Gollob, MH1
Rakowski, H1
O'Connor, MJ1
Miller, K1
Shaddy, RE1
Lin, KY1
Hanna, BD1
Ravishankar, C1
Rossano, JW1
Fischer, KL1
Sherrid, MV7
Shetty, A1
Winson, G1
Kim, B1
Musat, D2
Alviar, CL1
Homel, P1
Balaram, SK1
Swistel, DG1
Sorajja, P1
Ommen, SR2
Nishimura, RA2
Haruki, S2
Minami, Y4
Suzuki, A1
Hagiwara, N4
Verlinden, NJ1
Coons, JC1
Kajimoto, K4
Kawana, M2
Gibelin, P1
Yashiro, B1
Suzuki, T1
Imai, T1
Kasanuki, H4
Philippakis, AA1
Falk, RH1
Teraguchi, M1
Ikemoto, Y1
Kobayashi, Y1
Barac, I1
McKenna, WJ1
Elliott, PM1
Dickie, S1
Chojnowska, L1
Casey, S1
Elesber, A1
Rihal, CS1
Schaff, HV1
Holmes, DR1
Sirak, TE1
Gottdiener, JS1
Dibianco, R1
Bates, R1
Sauerbrunn, BJ1
Fletcher, RD1
Terrosu, P1
Franceschino, V1
Contini, GM1
Dore, L1
Ibba, GV1
Murgo, JP1
Pollick, C4
Matsubara, H1
Nakatani, S1
Nagata, S1
Ishikura, F1
Katagiri, Y1
Ohe, T1
Miyatake, K1
O'Gara, PT1
McGovern, BA1
Semigran, MJ1
Kimball, BP1
Bui, S1
Wigle, ED2
Gunsburg, DZ1
Pearle, G1
Pernat, A1
Pohar, B1
Horvat, M1
Niki, K3
Sugawara, M2
Asano, R1
Oka, T1
Kondoh, Y1
Tanino, S2
Iwade, K2
Magosaki, N1
Hosoda, S2
Tokudome, T1
Mizushige, K1
Ueda, T1
Sakamoto, S1
Matsuo, H1
Sakai, Y1
Hayashi, Y1
Tomobuchi, Y1
Hano, T1
Nishio, I1
Harada, T1
Imamura, K1
Matsuda, N1
Shite, J1
Yokota, Y1
Nakatani, M1
Takeuchi, Y1
Tsumura, Y1
Kawai, H1
Ueno, H1
Kawashima, T1
Honda, Y1
Hartmann, A1
Kühn, J1
Hopf, R1
Klepzig, H1
Standke, R1
Kober, G1
Maul, FD1
Hör, G1
Kaltenbach, M1
Blanchard, DG1
Ross, J1
Tanabe, T1
Takahashi, K1
Yoshioka, K1
Goto, Y1
Millaire, A1
Goullard, L1
Decoulx, E1
de Groote, P1
Houdas, Y1
Ducloux, G1
Nagashima, J1
Duncan, WJ1
Tyrrell, MJ1
Bharadwaj, BB1
Sumimoto, T1
Hamada, M1
Ohtani, T1
Shigematsu, Y1
Fujiwara, Y1
Sekiya, M1
Hiwada, K1
van der Wall, E1
Sherrid, M1
Delia, E1
Dwyer, E1
Kimball, B1
Henderson, M1
Miyajima, S1
Aizawa, Y1
Matsuoka, A1
Okabe, M1
Shibata, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy-- a Multicenter Randomized Control Trial[NCT02948998]Phase 4260 participants (Anticipated)Interventional2018-05-14Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for disopyramide and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
Lifestyle Modification and Medical Management of Hypertrophic Cardiomyopathy.
    Cardiology clinics, 2019, Volume: 37, Issue:1

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Cardiotonic Age

2019
Disopyramide for Hypertrophic Cardiomyopathy: A Pragmatic Reappraisal of an Old Drug.
    Pharmacotherapy, 2015, Volume: 35, Issue:12

    Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Humans

2015
Drug Therapy for Hypertrophic Cardiomypathy: Physiology and Practice.
    Current cardiology reviews, 2016, Volume: 12, Issue:1

    Topics: Animals; Cardiomyopathy, Hypertrophic; Disopyramide; Electrocardiography; Humans; Hypertension; Vent

2016
Pathophysiology of hypertrophic cardiomyopathy determines its medical treatment.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2006, Volume: 6 Suppl 2

    Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Hypertrophic; Decision Trees; Defibrillators, Implantab

2006
Effect of disopyramide on left ventricular pressure gradient in hypertrophic obstructive cardiomyopathy in comparison with propranolol--a case report.
    Angiology, 1999, Volume: 50, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Blood Pressure; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardio

1999
Hypertrophic cardiomyopathy: prognosis with medical or surgical therapy.
    Clinical cardiology, 1991, Volume: 14, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Child; D

1991

Trials

6 trials available for disopyramide and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
Salutary effect of disopyramide on left ventricular diastolic function in hypertrophic obstructive cardiomyopathy.
    Journal of the American College of Cardiology, 1995, Volume: 26, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Cardiac Catheterization; Cardiomyopathy, Hypertro

1995
Disopyramide improves the balance between myocardial oxygen supply and demand in patients with hypertrophic obstructive cardiomyopathy.
    Heart and vessels, 1997, Volume: 12, Issue:3

    Topics: Adult; Aged; Blood Flow Velocity; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Coronary Ci

1997
Effect of disopyramide on left ventricular pressure gradient in hypertrophic obstructive cardiomyopathy in comparison with propranolol--a case report.
    Angiology, 1999, Volume: 50, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Blood Pressure; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardio

1999
Evaluation of disopyramide and mexiletine used alone and in combination for ventricular arrhythmias in patients with and without overt heart disease.
    International journal of cardiology, 1991, Volume: 32, Issue:3

    Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Cardiomyopathy, Dilated; Cardiomyop

1991
Effect of disopyramide on systolic and early diastolic time intervals in patients with hypertrophic cardiomyopathy.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:5

    Topics: Adult; Aged; Blood Pressure; Cardiomyopathy, Hypertrophic; Diastole; Disopyramide; Female; Heart Rat

1991
Disopyramide in hypertrophic cardiomyopathy. II. Noninvasive assessment after oral administration.
    The American journal of cardiology, 1988, Dec-01, Volume: 62, Issue:17

    Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cardiomyopathy, Hypertrophic; Clinical Trials as

1988

Other Studies

41 other studies available for disopyramide and Cardiomyopathy, Hypertrophic Obstructive

ArticleYear
Bisoprolol for treatment of symptomatic patients with obstructive hypertrophic cardiomyopathy. The BASIC (bisoprolol AS therapy in hypertrophic cardiomyopathy) study.
    International journal of cardiology, 2022, May-01, Volume: 354

    Topics: Adult; Bisoprolol; Cardiomyopathy, Hypertrophic; Disopyramide; Humans; Retrospective Studies; Ventri

2022
Disopyramide is a safe and effective treatment for children with obstructive hypertrophic cardiomyopathy.
    International journal of cardiology, 2023, Jan-15, Volume: 371

    Topics: Adolescent; Adult; Cardiomyopathy, Hypertrophic; Child; Child, Preschool; Disopyramide; Echocardiogr

2023
Aficamten for Drug-Refractory Severe Obstructive Hypertrophic Cardiomyopathy in Patients Receiving Disopyramide: REDWOOD-HCM Cohort 3.
    Journal of cardiac failure, 2023, Volume: 29, Issue:11

    Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Heart Failure; Humans; Sequoia

2023
Left ventricular outflow tract pressure gradient changes after carvedilol-disopyramide cotherapy in a cat with hypertrophic obstructive cardiomyopathy.
    Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2020, Volume: 29

    Topics: Adrenergic beta-Antagonists; Animals; Cardiomyopathy, Hypertrophic; Carvedilol; Cat Diseases; Cats;

2020
[Disopyramide as coadjuvant treatment in obstructive hypertrophic cardiomyopathy].
    Anales de pediatria, 2021, Volume: 94, Issue:4

    Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Humans

2021
Prediction and Prevention of Sudden Death in Young Patients (<20 years) With Hypertrophic Cardiomyopathy.
    The American journal of cardiology, 2020, 08-01, Volume: 128

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Ca

2020
Safety of Outpatient Initiation of Disopyramide for Obstructive Hypertrophic Cardiomyopathy Patients.
    Journal of the American Heart Association, 2017, May-26, Volume: 6, Issue:6

    Topics: Action Potentials; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Data

2017
Disopyramide use in infants and children with hypertrophic cardiomyopathy.
    Cardiology in the young, 2018, Volume: 28, Issue:4

    Topics: Adolescent; Cardiomyopathy, Hypertrophic; Child; Child, Preschool; Disopyramide; Dose-Response Relat

2018
Treatment of obstructive hypertrophic cardiomyopathy symptoms and gradient resistant to first-line therapy with β-blockade or verapamil.
    Circulation. Heart failure, 2013, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiac Surgica

2013
Symptomatic obstructive hypertrophic cardiomyopathy.
    Circulation. Cardiovascular interventions, 2013, Oct-01, Volume: 6, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Cardiomyopathy, Hypertrophic; Diagnosis, Differential; Disease-Fr

2013
Effects of flecainide on left ventricular pressure gradient and symptoms in obstructive hypertrophic cardiomyopathy: a comparison of flecainide and disopyramide.
    Heart and vessels, 2015, Volume: 30, Issue:5

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Dose-Respo

2015
Synergistic effect of dual chamber pacing and disopyramide in obstructive hypertrophic cardiomyopathy.
    International journal of cardiology, 2010, May-28, Volume: 141, Issue:2

    Topics: Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiomyopathy, Hypertrophic; Combined Modality

2010
[Drug treatment for hypertrophic cardiomyopathy].
    Presse medicale (Paris, France : 1983), 2009, Volume: 38, Issue:6

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiomyop

2009
Possible acute and chronic synergistic effect of dual chamber pacing and disopyramide in obstructive hypertrophic cardiomyopathy: a case report.
    European journal of heart failure, 2010, Volume: 12, Issue:1

    Topics: Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Cardiomyopathy, Hypertrophic; Combined Mod

2010
Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline.
    The American journal of cardiology, 2010, Nov-01, Volume: 106, Issue:9

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography, D

2010
Cardiac amyloidosis mimicking hypertrophic cardiomyopathy with obstruction: treatment with disopyramide.
    Circulation, 2012, Apr-10, Volume: 125, Issue:14

    Topics: Aged; Amyloidosis; Cardiomyopathies; Cardiomyopathy, Hypertrophic; Disopyramide; Humans; Magnetic Re

2012
Effective disopyramide treatment in a boy with mid-ventricular hypertrophic obstructive cardiomyopathy.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:7

    Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Chest Pain; Child; Disopyramide; Heart Ventric

2002
Multicenter study of the efficacy and safety of disopyramide in obstructive hypertrophic cardiomyopathy.
    Journal of the American College of Cardiology, 2005, Apr-19, Volume: 45, Issue:8

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrop

2005
Utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy.
    The American journal of cardiology, 2008, Feb-15, Volume: 101, Issue:4

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Calcium Channel Blocke

2008
Oral disopyramide for the acute treatment of severe outflow obstruction in hypertrophic cardiomyopathy in the ICU setting.
    Chest, 2008, Volume: 133, Issue:5

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Dose-Respo

2008
Effects of disopyramide on left ventricular function: assessment by radionuclide cineangiography.
    The American journal of cardiology, 1983, May-15, Volume: 51, Issue:9

    Topics: Adult; Aged; Cardiomyopathy, Hypertrophic; Coronary Disease; Disopyramide; Heart; Heart Ventricles;

1983
[Beneficial effects of disopyramide on left ventricular outflow obstruction in a case of hypertrophic obstructive cardiomyopathy].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:1

    Topics: Angina Pectoris; Cardiomyopathy, Hypertrophic; Disopyramide; Female; Humans; Middle Aged

1984
Does outflow obstruction exist in hypertrophic cardiomyopathy?
    The New England journal of medicine, 1982, Oct-14, Volume: 307, Issue:16

    Topics: Cardiomyopathy, Hypertrophic; Disopyramide; Heart Ventricles; Humans; Myocardial Contraction

1982
Muscular subaortic stenosis: hemodynamic and clinical improvement after disopyramide.
    The New England journal of medicine, 1982, Oct-14, Volume: 307, Issue:16

    Topics: Administration, Oral; Adult; Aortic Stenosis, Subvalvular; Cardiomyopathy, Hypertrophic; Disopyramid

1982
Effects of disopyramide on diastolic function in hypertrophic cardiomyopathy.
    The American journal of cardiology, 1995, Mar-15, Volume: 75, Issue:8

    Topics: Cardiomyopathy, Hypertrophic; Diastole; Disopyramide; Humans; Ventricular Function, Left

1995
Effects of disopyramide on left ventricular diastolic function in hypertrophic cardiomyopathy.
    The American journal of cardiology, 1994, Aug-15, Volume: 74, Issue:4

    Topics: Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Diastole; Disopyramide; Female; Hemodynamics;

1994
Acute dose-response effects of intravenous disopyramide in hypertrophic obstructive cardiomyopathy.
    American heart journal, 1993, Volume: 125, Issue:6

    Topics: Adolescent; Adult; Aged; Cardiomyopathy, Hypertrophic; Disopyramide; Dose-Response Relationship, Dru

1993
Mid-systolic drop in left ventricular ejection velocity in obstructive hypertrophic cardiomyopathy--the lobster claw abnormality.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 1997, Volume: 10, Issue:7

    Topics: Acceleration; Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Blood Flow Velocity; Calciu

1997
Heart conduction disturbances and cardiovascular collapse after disopyramide and low-dose metoprolol in a patient with hypertrophic obstructive cardiomyopathy.
    Journal of electrocardiology, 1997, Volume: 30, Issue:4

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Dis

1997
Dynamic outflow obstruction due to the transient extensive left ventricular wall motion abnormalities caused by acute myocarditis in a patient with hypertrophic cardiomyopathy: reduction in ventricular afterload by disopyramide.
    Japanese circulation journal, 1999, Volume: 63, Issue:8

    Topics: Acute Disease; Aged; Cardiomyopathy, Hypertrophic; Coronary Angiography; Disopyramide; Echocardiogra

1999
An equation to predict the changes in peak left ventricular pressure in hypertrophic obstructive cardiomyopathy after treatment: application to the administration of disopyramide.
    Heart and vessels, 1999, Volume: 14, Issue:2

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiomyopathy, Hypertrophic; Disopyra

1999
[Efficacy of continuous intravenous drip infusion of disopyramide in hypertrophic obstructive cardiomyopathy during cardiogenic shock: a case report].
    Journal of cardiology, 2000, Volume: 35, Issue:3

    Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Female; Humans; Infusions, Intra

2000
[Clinical and echocardiographic evaluation of the effects of atrial defibrillation in patients with idiopathic cardiomyopathy].
    Journal of cardiology, 1992, Volume: 22, Issue:1

    Topics: Adult; Atrial Fibrillation; Blood Pressure; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; D

1992
Effect of propranolol and disopyramide on left ventricular function at rest and during exercise in hypertrophic cardiomyopathy.
    Cardiology, 1992, Volume: 80, Issue:2

    Topics: Administration, Oral; Adult; Cardiac Output; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiog

1992
Efficiency of disopyramide in hypertrophic cardiomyopathy during stress states.
    The American journal of cardiology, 1992, Feb-01, Volume: 69, Issue:4

    Topics: Adolescent; Adult; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography, Doppler; Exercise;

1992
[Doppler and echocardiographic assessments of effects of disopyramide on non-obstructive hypertrophic cardiomyopathy].
    Journal of cardiology, 1991, Volume: 21, Issue:1

    Topics: Adult; Aged; Blood Flow Velocity; Blood Pressure; Cardiomyopathy, Hypertrophic; Diastole; Disopyrami

1991
Disopyramide as a negative inotrope in obstructive cardiomyopathy in children.
    The Canadian journal of cardiology, 1991, Volume: 7, Issue:2

    Topics: Cardiomyopathy, Hypertrophic; Carnitine; Child; Disopyramide; Ductus Arteriosus, Patent; Echocardiog

1991
Disopyramide in hypertrophic cardiomyopathy.
    The American journal of cardiology, 1990, Jan-15, Volume: 65, Issue:3

    Topics: Cardiomyopathy, Hypertrophic; Disopyramide; Exercise; Heart; Humans; Stroke Volume

1990
Oral disopyramide therapy for obstructive hypertrophic cardiomyopathy.
    The American journal of cardiology, 1988, Nov-15, Volume: 62, Issue:16

    Topics: Aged; Aged, 80 and over; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography; Echocardiogra

1988
Disopyramide in hypertrophic cardiomyopathy. I. Hemodynamic assessment after intravenous administration.
    The American journal of cardiology, 1988, Dec-01, Volume: 62, Issue:17

    Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiac Output; Cardiomyopathy, Hypertrophic; Disopyramide;

1988
Danger of use of disopyramide in patients with hypertrophic obstructive cardiomyopathy. An electrophysiologic study.
    Japanese heart journal, 1988, Volume: 29, Issue:1

    Topics: Cardiac Pacing, Artificial; Cardiomyopathy, Hypertrophic; Disopyramide; Drug Evaluation; Electrocard

1988