disopyramide has been researched along with Cardiomyopathy, Dilated in 4 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Cardiomyopathy, Dilated: A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with aprindine or mexiletine was effective in 7 (50%) of the 14 patients who did not respond to procainamide and/or disopyramide." | 1.28 | Analysis of ventricular arrhythmias in patients with dilated cardiomyopathy--relationship between the effects of antiarrhythmic agents and severity of myocardial lesions. ( Fukuzaki, H; Takarada, A; Yokota, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shite, J | 1 |
| Yokota, Y | 2 |
| Nakatani, M | 1 |
| Takeuchi, Y | 1 |
| Tsumura, Y | 1 |
| Kawai, H | 1 |
| Ueno, H | 1 |
| Kawashima, T | 1 |
| Honda, Y | 1 |
| Tanabe, T | 1 |
| Takahashi, K | 1 |
| Yoshioka, K | 1 |
| Goto, Y | 1 |
| Takarada, A | 1 |
| Fukuzaki, H | 1 |
| Goedel-Meinen, L | 1 |
| Hofmann, M | 1 |
| Schmidt, G | 1 |
| Barthel, P | 1 |
| Baedeker, W | 1 |
| Blömer, H | 1 |
2 trials available for disopyramide and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
Evaluation of disopyramide and mexiletine used alone and in combination for ventricular arrhythmias in patients with and without overt heart disease.
Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Cardiomyopathy, Dilated; Cardiomyop | 1991 |
[Effect of class I anti-arrhythmia agents on the signal-averaged ECG].
Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Clinical Trials as Topic; Coronary Disease; Disopyr | 1988 |
2 other studies available for disopyramide and Cardiomyopathy, Dilated
| Article | Year |
|---|---|
[Clinical and echocardiographic evaluation of the effects of atrial defibrillation in patients with idiopathic cardiomyopathy].
Topics: Adult; Atrial Fibrillation; Blood Pressure; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; D | 1992 |
Analysis of ventricular arrhythmias in patients with dilated cardiomyopathy--relationship between the effects of antiarrhythmic agents and severity of myocardial lesions.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Disop | 1990 |