disopyramide has been researched along with Cardiac Diseases in 17 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Medication dosages, dosing intervals, and time elapsed from last dosage until blood sampling were determined." | 1.27 | Long-term antiarrhythmic therapy. Problem of low drug levels and patient noncompliance. ( Fuster, V; Goldman, ME; Kupersmith, J; Schweitzer, P; Squire, A; Stern, EH, 1984) |
| "Disopyramide kinetics were studied in 30 patients with normal to severely impaired renal function (endogenous creatinine clearance 7." | 1.27 | Disopyramide kinetics in renal impairment: determinants of interindividual variability. ( Burk, M; Peters, U, 1983) |
| "The antiarrhythmic agent disopyramide, in a dosage of 200 mg/8 h, was given to 7 cardiac patients." | 1.26 | Disopyramide plasma levels in cardiac patients on maintenance therapy. ( Landmark, K; Larsen, A; Storstein, L, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (82.35) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Squire, A | 1 |
| Goldman, ME | 1 |
| Kupersmith, J | 1 |
| Stern, EH | 1 |
| Fuster, V | 1 |
| Schweitzer, P | 1 |
| Karim, A | 1 |
| Nissen, C | 1 |
| Azarnoff, DL | 1 |
| Kowey, PR | 1 |
| Friedman, PL | 1 |
| Podrid, PJ | 1 |
| Zielonka, J | 1 |
| Lown, B | 1 |
| Wynne, J | 1 |
| Holman, BL | 1 |
| Burk, M | 1 |
| Peters, U | 1 |
| David, BM | 1 |
| Madsen, BW | 1 |
| Ilett, KF | 1 |
| Landmark, K | 1 |
| Storstein, L | 1 |
| Larsen, A | 1 |
| Pennock, RS | 1 |
| Sutton, R | 1 |
| Fujimoto, Y | 1 |
| Fukuki, M | 1 |
| Hirokane, Y | 1 |
| Kotake, H | 1 |
| Mashiba, H | 1 |
| Tanabe, T | 1 |
| Takahashi, K | 1 |
| Yoshioka, K | 1 |
| Goto, Y | 1 |
| Suzuki, K | 1 |
| Au, PK | 1 |
| Bhandari, AK | 1 |
| Bream, R | 1 |
| Schreck, D | 1 |
| Siddiqi, R | 1 |
| Rahimtoola, SH | 1 |
| Proelss, HF | 1 |
| Townsend, TB | 1 |
| Sakata, K | 1 |
| Ishigaki, S | 1 |
| Sakata, M | 1 |
| Shaw, LM | 1 |
| Altman, R | 1 |
| Thompson, BC | 1 |
| Fields, L | 1 |
| Lisin, N | 1 |
| Andriange, M | 1 |
| Vandenbosch, R | 1 |
| Carlier, J | 1 |
1 review available for disopyramide and Cardiac Diseases
| Article | Year |
|---|---|
Clinical pharmacokinetics of disopyramide.
Topics: Animals; Biological Availability; Biotransformation; Blood Proteins; Disopyramide; Heart Diseases; H | 1982 |
1 trial available for disopyramide and Cardiac Diseases
| Article | Year |
|---|---|
Evaluation of disopyramide and mexiletine used alone and in combination for ventricular arrhythmias in patients with and without overt heart disease.
Topics: Administration, Oral; Adult; Aged; Cardiac Complexes, Premature; Cardiomyopathy, Dilated; Cardiomyop | 1991 |
15 other studies available for disopyramide and Cardiac Diseases
| Article | Year |
|---|---|
Long-term antiarrhythmic therapy. Problem of low drug levels and patient noncompliance.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Disopyramide; Female; Heart Diseases; Humans; Male; Middle Aged | 1984 |
Use of radionuclide ventriculography for assessment of changes in myocardial performance induced by disopyramide phosphate.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Disopyramide; Female; Heart; Heart Diseases; Humans; | 1982 |
Disopyramide kinetics in renal impairment: determinants of interindividual variability.
Topics: Adult; Aged; Creatinine; Disopyramide; Dose-Response Relationship, Drug; Drug Evaluation; Female; He | 1983 |
Cardiac problems caused by disopyramide.
Topics: Disopyramide; Heart Diseases; Humans; Pyridines | 1981 |
Plasma binding of disopyramide.
Topics: Blood Proteins; Disopyramide; Heart Diseases; Humans; Kinetics; Myocardial Infarction; Protein Bindi | 1980 |
Disopyramide plasma levels in cardiac patients on maintenance therapy.
Topics: Adult; Aged; Disopyramide; Female; Half-Life; Heart Diseases; Humans; Male; Middle Aged; Pyridines; | 1979 |
How useful are serum levels of cardiac drugs?
Topics: Anti-Arrhythmia Agents; Digitalis Glycosides; Disopyramide; Heart Diseases; Humans; Lidocaine; Pheny | 1978 |
Haemodynamics of intravenous disopyramide.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Disopyramide; Female; Heart Diseases; Heart Rate; Heart | 1976 |
Clinical study on coupling interval of ventricular premature contraction in patients with organic heart disease.
Topics: Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography, Ambulatory; Femal | 1991 |
Clinical features of sustained ventricular tachycardia among various underlying heart diseases.
Topics: Adult; Disopyramide; Electroencephalography; Heart Diseases; Heart Rate; Heart Ventricles; Hemodynam | 1990 |
Proarrhythmic effects of antiarrhythmic drugs during programmed ventricular stimulation in patients without ventricular tachycardia.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Disop | 1987 |
Simultaneous liquid-chromatographic determination of five antiarrhythmic drugs and their major active metabolites in serum.
Topics: Anti-Arrhythmia Agents; Buffers; Chromatography, High Pressure Liquid; Disopyramide; Ethylamines; He | 1986 |
Distribution of lidocaine and disopyramide in human blood and tissue, a case report of death caused by spinal anesthesia.
Topics: Anesthesia, Spinal; Animals; Brain; Child; Disopyramide; Female; Heart Diseases; Humans; Kidney; Lid | 1988 |
Factors affecting the binding of disopyramide to serum proteins.
Topics: Blood Proteins; Chromatography, High Pressure Liquid; Dialysis; Disopyramide; Heart Diseases; Humans | 1985 |
[Treatment of disturbances of cardiac rhythm using intravenous disopyramide].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Brad | 1974 |