Page last updated: 2024-10-26

disopyramide and Breathlessness

disopyramide has been researched along with Breathlessness in 5 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Research Excerpts

ExcerptRelevanceReference
"Amrubicin is a novel synthetic 9-aminoanthracycline derivative and is converted enzymatically to its C-13 hydroxy metabolite, amrubicinol, whose cytotoxic activity is 10-100 times that of amrubicin."2.72Phase I and pharmacokinetic study of amrubicin, a synthetic 9-aminoanthracycline, in patients with refractory or relapsed lung cancer. ( Fujii, S; Hamada, A; Kishi, H; Matsunaga, Y; Mori, I; Okamoto, I; Saito, H; Sasaki, J; Semba, H; Uramoto, H; Yamagata, H, 2006)
"Drug treatment of hypertrophic cardiomyopathy is the first-line treatment, at the onset of clinical signs and symptoms."1.35[Drug treatment for hypertrophic cardiomyopathy]. ( Gibelin, P, 2009)
" Searle), literature demonstrating its efficacy in maintaining uniform serum drug levels over a 12-h dosing interval is derived from only normal healthy volunteers."1.27Serum drug concentrations and adverse effects in cardiac patients after administration of a new controlled-release disopyramide preparation. ( Zema, MJ, 1984)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sorajja, P1
Ommen, SR1
Nishimura, RA1
Pasquale, F1
Tomé-Esteban, MT1
Morgagni, R1
Elliott, P1
Gibelin, P1
Okamoto, I1
Hamada, A1
Matsunaga, Y1
Sasaki, J1
Fujii, S1
Uramoto, H1
Yamagata, H1
Mori, I1
Kishi, H1
Semba, H1
Saito, H1
Zema, MJ1

Trials

1 trial available for disopyramide and Breathlessness

ArticleYear
Phase I and pharmacokinetic study of amrubicin, a synthetic 9-aminoanthracycline, in patients with refractory or relapsed lung cancer.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:3

    Topics: Aged; Anthracyclines; Antineoplastic Agents; Area Under Curve; Atrial Fibrillation; Carcinoma, Non-S

2006

Other Studies

4 other studies available for disopyramide and Breathlessness

ArticleYear
Symptomatic obstructive hypertrophic cardiomyopathy.
    Circulation. Cardiovascular interventions, 2013, Oct-01, Volume: 6, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Cardiomyopathy, Hypertrophic; Diagnosis, Differential; Disease-Fr

2013
Provokable left ventricular outflow tract obstruction in a patient without hypertrophy.
    Nature reviews. Cardiology, 2009, Volume: 6, Issue:4

    Topics: Angina Pectoris; Anti-Arrhythmia Agents; Atenolol; Cardiac Pacing, Artificial; Diagnostic Imaging; D

2009
[Drug treatment for hypertrophic cardiomyopathy].
    Presse medicale (Paris, France : 1983), 2009, Volume: 38, Issue:6

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiomyop

2009
Serum drug concentrations and adverse effects in cardiac patients after administration of a new controlled-release disopyramide preparation.
    Therapeutic drug monitoring, 1984, Volume: 6, Issue:2

    Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Delayed-Action Preparations; Diarrhea; Diso

1984