disopyramide has been researched along with Anesthesia in 5 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of intravenous doses of Org 6001 and disopyramide (10 mg/kg) known to confer protection against early postligation-induced arrhythmias in the anaesthetized rat when given prophylactically, were assessed following postligation administration." | 7.66 | The effects of postligation administration of ORG 6001 and disopyramide on early ischaemia-induced arrhythmias in the anaesthetized rat. ( Marshall, RJ; Muir, AW; Winslow, E, 1982) |
| "Antiarrhythmic effects and cardiovascular effects of pilsicainide hydrochloride were compared with those of disopyramide in a canine model of coronary ligation-induced ventricular arrhythmias and anesthetized dogs." | 3.70 | [Antiarrhythmic effects of pilsicainide hydrochloride and effects on cardiac function and ECG in dogs: comparison with disopyramide]. ( Hayashi, Y; Hidaka, T; Inomata, N; Inoue, T; Komoriya, K, 2000) |
| "The effects of intravenous doses of Org 6001 and disopyramide (10 mg/kg) known to confer protection against early postligation-induced arrhythmias in the anaesthetized rat when given prophylactically, were assessed following postligation administration." | 3.66 | The effects of postligation administration of ORG 6001 and disopyramide on early ischaemia-induced arrhythmias in the anaesthetized rat. ( Marshall, RJ; Muir, AW; Winslow, E, 1982) |
| " During dosing (10 mg kg-1 twice a day for 10 days) no effects on the electrocardiogram, monitored in conscious animals, were observed despite modest reductions (15-18%) in the maximum rate of depolarization of papillary muscle excised 1 or 6 h after completion of the dosing regime." | 1.28 | Antiarrhythmic, electrophysiological and haemodynamic effects of prolonged oral dosing with Org 7797 in the anaesthetized rat. ( Delbressine, L; Harris, N; Kane, KA; Muir, AW; Winslow, E, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Marshall, RJ | 1 |
| Muir, AW | 2 |
| Winslow, E | 2 |
| Hidaka, T | 1 |
| Inoue, T | 1 |
| Komoriya, K | 1 |
| Hayashi, Y | 1 |
| Inomata, N | 1 |
| Delbressine, L | 1 |
| Harris, N | 1 |
| Kane, KA | 1 |
| Konishi, T | 1 |
| Kadoya, M | 1 |
| Ikeguchi, S | 1 |
| Sakai, K | 1 |
| Tamamura, T | 1 |
| Kawai, C | 1 |
| Wood, M | 1 |
1 review available for disopyramide and Anesthesia
| Article | Year |
|---|---|
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca | 1986 |
4 other studies available for disopyramide and Anesthesia
| Article | Year |
|---|---|
The effects of postligation administration of ORG 6001 and disopyramide on early ischaemia-induced arrhythmias in the anaesthetized rat.
Topics: Androstanols; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Cor | 1982 |
[Antiarrhythmic effects of pilsicainide hydrochloride and effects on cardiac function and ECG in dogs: comparison with disopyramide].
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disease Models, | 2000 |
Antiarrhythmic, electrophysiological and haemodynamic effects of prolonged oral dosing with Org 7797 in the anaesthetized rat.
Topics: Action Potentials; Administration, Oral; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, C | 1992 |
Combined effect of disopyramide and bethanechol: use of bethanechol to prevent anticholinergic side effects of disopyramide without reduction of antiarrhythmic efficacy.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bethanechol Compounds; Blood Pre | 1989 |