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disopyramide and Aging

disopyramide has been researched along with Aging in 4 studies

Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" The results indicate that it might be advisable to reduce the dosage of disopyramide by approximately 30% in elderly non-smokers compared with young subjects."1.27The influence of age and smoking on the elimination of disopyramide. ( Angelo, HR; Bonde, J; Bødtker, S; Kampmann, JP; Pedersen, LE; Svendsen, TL, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Holt, DW1
Hayler, AM1
Healey, GF1
Mokler, CM1
Lowenthal, DT1
Affrime, MB1
Bonde, J1
Pedersen, LE1
Bødtker, S1
Angelo, HR1
Svendsen, TL1
Kampmann, JP1

Other Studies

4 other studies available for disopyramide and Aging

ArticleYear
Effect of age and plasma concentrations of albumin and alpha 1-acid glycoprotein on protein binding of disopyramide.
    British journal of clinical pharmacology, 1983, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Disopyramide; Female; Humans; Infant; Infan

1983
Lack of an aging effect on responses to disopyramide in rabbit ventricle. A brief note.
    Mechanisms of ageing and development, 1982, Volume: 18, Issue:2

    Topics: Aging; Animals; Disopyramide; Electric Stimulation; Electrophysiology; Female; Heart; Heart Conducti

1982
Cardiovascular drugs for the geriatric patient.
    Geriatrics, 1981, Volume: 36, Issue:8

    Topics: Aged; Aging; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular Physiological Phenomena;

1981
The influence of age and smoking on the elimination of disopyramide.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:5

    Topics: Adult; Aged; Aging; Disopyramide; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Oroso

1985