disopyramide has been researched along with Acute Disease in 14 studies
Disopyramide: A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
disopyramide : A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "473 patients with suspected acute myocardial infarction were entered into a randomised, double-blind, placebo-controlled comparison of disopyramide phosphate, 150 mg three times a day, and oxprenolol, 40 mg three times a day." | 9.05 | Randomised placebo-controlled trial comparing oxprenolol with disopyramide phosphate in immediate treatment of suspected myocardial infarction. ( Banks, DC; Hampton, JR; Mitchell, JR; Roland, JM; Rowley, JM; Wilcox, RG, 1980) |
| "Patients with acute myocardial infarction admitted to a coronary care unit were given either intravenous and oral disopyramide or matching placebo on admission and throughout their hospital stay." | 9.05 | Intravenous and oral disopyramide after myocardial infarction. ( Barnes, PC; Haybyrne, T; Nicholls, DP, 1980) |
| "Patients with acute myocardial infarction admitted to open wards of three hospitals were given either oral disopyramide (100 mg four times daily) or matching placebo, prophylactically, for seven days." | 9.04 | Oral disopyramide for the prevention of arrhythmias in patients with acute myocardial infarction admitted to open wards. ( Besterman, EM; Carmichael, DJ; Gillham, AD; Griffiths, JW; Kidner, PH; Summers, GD; Zainal, N, 1977) |
| "The incidence of ventricular arrhythmias after myocardial infarction was compared in a double blind study of disopyramide (33 patients), aprindine (34 patients) and placebo (31 patients)." | 9.04 | Effects of disopyramide and aprindine on arrhythmias after acute myocardial infarction. ( Chaudron, JM; Pouleur, H; Reyns, P, 1977) |
| "Twenty-six patients with clinically significant ventricular arrhythmias were randomly assigned to treatment with either intravenous disopyramide or lidocaine; crossover to the other agent was permitted in nine cases of primary drug failure." | 9.04 | Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial. ( Fozzard, HA; Rawling, DA; Sbarbaro, JA, 1979) |
| "The efficacy of intravenous disopyramide was studied during 200 episodes of supraventricular and ventricular arrhythmias in 160 patients, mainly presenting with acute myocardial infarction or cardiac failure." | 7.66 | Efficacy of intravenous disopyramide in acute cardiac arrhythmias. ( De Backer, M; Kahn, RJ; Stoupel, E, 1981) |
| "Disopyramide, a new anti-arrhythmic drug, has been assessed in twenty-one episodes of cardiac arrhythmia secondary to acute ischaemic heart disease which failed to respond to more conventional suppressive therapy with lignocaine and other standard drugs." | 7.65 | The use of disopyramide in resistant cardiac arrhythmias due to acute ischaemic heart disease. ( Sandler, G, 1977) |
| "Flecainide was as effective as the combination of digoxin and disopyramide and it acted significantly faster and was associated with fewer relapses." | 6.66 | Flecainide compared with a combination of digoxin and disopyramide for acute atrial arrhythmias after cardiopulmonary bypass. ( Campbell, TJ; Gavaghan, TP; Kelly, RP; Koegh, AM; Morgan, JJ; Thorburn, C, 1988) |
| "473 patients with suspected acute myocardial infarction were entered into a randomised, double-blind, placebo-controlled comparison of disopyramide phosphate, 150 mg three times a day, and oxprenolol, 40 mg three times a day." | 5.05 | Randomised placebo-controlled trial comparing oxprenolol with disopyramide phosphate in immediate treatment of suspected myocardial infarction. ( Banks, DC; Hampton, JR; Mitchell, JR; Roland, JM; Rowley, JM; Wilcox, RG, 1980) |
| "Patients with acute myocardial infarction admitted to a coronary care unit were given either intravenous and oral disopyramide or matching placebo on admission and throughout their hospital stay." | 5.05 | Intravenous and oral disopyramide after myocardial infarction. ( Barnes, PC; Haybyrne, T; Nicholls, DP, 1980) |
| "Patients with acute myocardial infarction admitted to open wards of three hospitals were given either oral disopyramide (100 mg four times daily) or matching placebo, prophylactically, for seven days." | 5.04 | Oral disopyramide for the prevention of arrhythmias in patients with acute myocardial infarction admitted to open wards. ( Besterman, EM; Carmichael, DJ; Gillham, AD; Griffiths, JW; Kidner, PH; Summers, GD; Zainal, N, 1977) |
| "The incidence of ventricular arrhythmias after myocardial infarction was compared in a double blind study of disopyramide (33 patients), aprindine (34 patients) and placebo (31 patients)." | 5.04 | Effects of disopyramide and aprindine on arrhythmias after acute myocardial infarction. ( Chaudron, JM; Pouleur, H; Reyns, P, 1977) |
| "Twenty-six patients with clinically significant ventricular arrhythmias were randomly assigned to treatment with either intravenous disopyramide or lidocaine; crossover to the other agent was permitted in nine cases of primary drug failure." | 5.04 | Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial. ( Fozzard, HA; Rawling, DA; Sbarbaro, JA, 1979) |
| "The efficacy of intravenous disopyramide was studied during 200 episodes of supraventricular and ventricular arrhythmias in 160 patients, mainly presenting with acute myocardial infarction or cardiac failure." | 3.66 | Efficacy of intravenous disopyramide in acute cardiac arrhythmias. ( De Backer, M; Kahn, RJ; Stoupel, E, 1981) |
| "Disopyramide, a new anti-arrhythmic drug, has been assessed in twenty-one episodes of cardiac arrhythmia secondary to acute ischaemic heart disease which failed to respond to more conventional suppressive therapy with lignocaine and other standard drugs." | 3.65 | The use of disopyramide in resistant cardiac arrhythmias due to acute ischaemic heart disease. ( Sandler, G, 1977) |
| "Flecainide was as effective as the combination of digoxin and disopyramide and it acted significantly faster and was associated with fewer relapses." | 2.66 | Flecainide compared with a combination of digoxin and disopyramide for acute atrial arrhythmias after cardiopulmonary bypass. ( Campbell, TJ; Gavaghan, TP; Kelly, RP; Koegh, AM; Morgan, JJ; Thorburn, C, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (78.57) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wilcox, RG | 1 |
| Rowley, JM | 1 |
| Hampton, JR | 1 |
| Mitchell, JR | 1 |
| Roland, JM | 1 |
| Banks, DC | 1 |
| Nicholls, DP | 1 |
| Haybyrne, T | 1 |
| Barnes, PC | 1 |
| De Backer, M | 1 |
| Stoupel, E | 1 |
| Kahn, RJ | 1 |
| Jaeger, A | 1 |
| Sauder, P | 1 |
| Tempe, JD | 1 |
| Mantz, JM | 1 |
| Accornero, F | 1 |
| Pellanda, A | 1 |
| Ruffini, C | 1 |
| Bonelli, S | 1 |
| Latini, R | 1 |
| Kishikawa, T | 1 |
| Maruyama, T | 1 |
| Kaji, Y | 1 |
| Sasaki, Y | 1 |
| Kanaya, S | 1 |
| Fujino, T | 1 |
| Niho, Y | 1 |
| Ishihara, Y | 1 |
| Sakai, Y | 1 |
| Hayashi, Y | 1 |
| Tomobuchi, Y | 1 |
| Hano, T | 1 |
| Nishio, I | 1 |
| Zainal, N | 1 |
| Carmichael, DJ | 1 |
| Griffiths, JW | 1 |
| Besterman, EM | 1 |
| Kidner, PH | 1 |
| Gillham, AD | 1 |
| Summers, GD | 1 |
| Pouleur, H | 1 |
| Chaudron, JM | 1 |
| Reyns, P | 1 |
| Story, JR | 1 |
| Abdulla, AM | 1 |
| Frank, MJ | 1 |
| Sbarbaro, JA | 1 |
| Rawling, DA | 1 |
| Fozzard, HA | 1 |
| Sandler, G | 1 |
| Gavaghan, TP | 1 |
| Koegh, AM | 1 |
| Kelly, RP | 1 |
| Campbell, TJ | 1 |
| Thorburn, C | 1 |
| Morgan, JJ | 1 |
8 trials available for disopyramide and Acute Disease
| Article | Year |
|---|---|
Randomised placebo-controlled trial comparing oxprenolol with disopyramide phosphate in immediate treatment of suspected myocardial infarction.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Clinical Trials as Topic; Disopyra | 1980 |
Intravenous and oral disopyramide after myocardial infarction.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Di | 1980 |
Effects of oral repetitive loading of disopyramide on acute-onset atrial fibrillation with concurrent monitoring of serum drug concentration.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disop | 1999 |
Oral disopyramide for the prevention of arrhythmias in patients with acute myocardial infarction admitted to open wards.
Topics: Acute Disease; Administration, Oral; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyram | 1977 |
Anti-dysrhythmic treatment in acute myocardial infarction.
Topics: Acute Disease; Administration, Oral; Atenolol; Clinical Trials as Topic; Disopyramide; Double-Blind | 1979 |
Effects of disopyramide and aprindine on arrhythmias after acute myocardial infarction.
Topics: Acute Disease; Adult; Aged; Aprindine; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; | 1977 |
Suppression of ventricular arrhythmias with intravenous disopyramide and lidocaine: efficacy comparison in a randomized trial.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Humans; Injections | 1979 |
Flecainide compared with a combination of digoxin and disopyramide for acute atrial arrhythmias after cardiopulmonary bypass.
Topics: Acute Disease; Aged; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Clin | 1988 |
6 other studies available for disopyramide and Acute Disease
| Article | Year |
|---|---|
Efficacy of intravenous disopyramide in acute cardiac arrhythmias.
Topics: Acute Disease; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; C | 1981 |
[Acute voluntary or accidental disopyramide poisoning. A multicentric study of 106 cases (author's transl)].
Topics: Acute Disease; Brain Diseases; Cardiovascular Diseases; Disopyramide; Humans; Pyridines; Time Factor | 1981 |
Prolonged cardiopulmonary resuscitation during acute disopyramide poisoning.
Topics: Acute Disease; Adolescent; Cardiopulmonary Resuscitation; Disopyramide; Drug Overdose; Electrocardio | 1993 |
Dynamic outflow obstruction due to the transient extensive left ventricular wall motion abnormalities caused by acute myocarditis in a patient with hypertrophic cardiomyopathy: reduction in ventricular afterload by disopyramide.
Topics: Acute Disease; Aged; Cardiomyopathy, Hypertrophic; Coronary Angiography; Disopyramide; Echocardiogra | 1999 |
Cardiogenic shock and disopyramide phosphate.
Topics: Acute Disease; Arrhythmias, Cardiac; Cardiac Output; Disopyramide; Heart Failure; Humans; Kidney Fai | 1979 |
The use of disopyramide in resistant cardiac arrhythmias due to acute ischaemic heart disease.
Topics: Acute Disease; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Humans; Pyridines | 1977 |