diquat has been researched along with Chemical and Drug Induced Liver Injury in 15 studies
*Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, Y; Ji, S; Jia, P; Li, Y; Wang, T; Xu, J; Zhang, H | 1 |
| Chen, Y; Wang, T; Zhang, H | 1 |
| He, L; Wu, C; Wu, X; Yin, Y; Zhang, Y; Zhou, X | 1 |
| Farhood, A; Hong, JY; Jaeschke, H; Lebofsky, M | 1 |
| Klaassen, CD; Wu, KC; Zhang, Y | 1 |
| Gupta, S; Hansen, TN; Rogers, LK; Smith, CV; Welty, SE | 1 |
| Alenda, C; Gutiérrez, A; Peiró, AM; Pérez-Mateo, M; Ramírez, A; Such, J; Zapater, P | 1 |
| Burk, RF; Lane, JM; Lawrence, RA | 1 |
| Geske, RS; Gupta, S; Husser, RC; Smith, CV; Welty, SE | 1 |
| Benzick, AE; Jaeschke, H | 1 |
| Donarski, WJ; Jolly, RA; Ochoa, R; Petry, TW; Wolfgang, GH | 1 |
| DeGray, JA; Mason, RP; Rao, DN | 1 |
| Cotgreave, IA; Lindeke, B; Moldéus, P; Sun, YP | 1 |
| Hughes, H; Mitchell, JR; Smith, CV; Tsokos-Kuhn, JO | 1 |
1 trial(s) available for diquat and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Diquat; Energy Metabolism; Gene Expression Regulation; Glutathione; Herbicides; Liver; Male; Mitochondrial Diseases; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Superoxides; Swine | 2020 |
14 other study(ies) available for diquat and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Pterostilbene as a protective antioxidant attenuates diquat-induced liver injury and oxidative stress in 21-day-old broiler chickens.
Topics: Animal Feed; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chickens; Diet; Dietary Supplements; Diquat; Dose-Response Relationship, Drug; Herbicides; Male; Oxidative Stress; Poultry Diseases; Protective Agents; Random Allocation; Stilbenes | 2020 |
Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.
Topics: Animals; Antioxidants; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cycloleucine; Cystathionine beta-Synthase; Defoliants, Chemical; Dietary Supplements; Diquat; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione; Hepatocytes; Homocysteine; Male; Methionine; Methionine Adenosyltransferase; Mice, Inbred C57BL; Oxidative Stress; Random Allocation; RNA Interference; Serine; Specific Pathogen-Free Organisms | 2017 |
Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation.
Topics: Alanine Transaminase; Aldehydes; Animals; Antifibrinolytic Agents; Apoptosis; Caspases; Chemical and Drug Induced Liver Injury; Diquat; Disease Models, Animal; DNA Fragmentation; Endotoxins; Galactosamine; Glutathione Disulfide; Hepatocytes; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Liver Diseases; Male; Necrosis; Oxidative Stress; Rats; Rats, Inbred F344; Superoxides; Vitamin K 3 | 2009 |
Nrf2 protects against diquat-induced liver and lung injury.
Topics: Alanine Transaminase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Diquat; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Herbicides; Inbreeding; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Survival Analysis; Thiobarbituric Acid Reactive Substances | 2012 |
Nuclear and nucleolar glutathione reductase, peroxidase, and transferase activities in livers of male and female Fischer-344 rats.
Topics: Animals; Blotting, Western; Cell Nucleolus; Cell Nucleus; Chemical and Drug Induced Liver Injury; Diquat; DNA; Female; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Herbicides; Liver; Male; Mice; Necrosis; Rats; Rats, Inbred F344; Reactive Oxygen Species | 2002 |
Hepatotoxicity related to paraquat and diquat absorption through intact skin.
Topics: Aged; Biopsy; Chemical and Drug Induced Liver Injury; Cholangiopancreatography, Magnetic Resonance; Curcumin; Diquat; Enzyme Inhibitors; Follow-Up Studies; Herbicides; Humans; Male; Paraquat; Skin Absorption; Ultrasonography, Doppler | 2007 |
Liver necrosis and lipid peroxidation in the rat as the result of paraquat and diquat administration. Effect of selenium deficiency.
Topics: Animals; Chemical and Drug Induced Liver Injury; Diquat; Ethane; Kidney Diseases; Lipid Peroxides; Liver Diseases; Male; Necrosis; Paraquat; Pyridinium Compounds; Rats; Selenium | 1980 |
Sex differences in diquat-induced hepatic necrosis and DNA fragmentation in Fischer 344 rats.
Topics: Alanine Transaminase; Animals; Bile Ducts; Blotting, Western; Chemical and Drug Induced Liver Injury; Diquat; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Herbicides; Male; Necrosis; Proteins; Rats; Rats, Inbred F344; Sex Characteristics; Superoxide Dismutase | 2000 |
Pathophysiological consequences of enhanced intracellular superoxide formation in isolated perfused rat liver.
Topics: Animals; Bile; Carmustine; Chemical and Drug Induced Liver Injury; Diquat; Ferrous Compounds; Glutathione; Glutathione Reductase; Ketones; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred F344; Superoxides | 1992 |
Antioxidant-dependent inhibition of diquat-induced toxicity in vivo.
Topics: Alanine Transaminase; Animals; Antioxidants; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chromans; Diquat; Kidney Cortex Necrosis; Kidney Diseases; Lipid Peroxidation; Lipid Peroxides; Liver; Liver Diseases; Male; Necrosis; Peritoneal Cavity; Phenylenediamines; Piperazines; Pregnatrienes; Rats; Rats, Inbred F344; Time Factors | 1992 |
Reduction of paraquat and related bipyridylium compounds to free radical metabolites by rat hepatocytes.
Topics: Animals; Benzyl Viologen; Cations; Chemical and Drug Induced Liver Injury; Cobalt; Cytochrome P-450 Enzyme System; Diquat; Electron Spin Resonance Spectroscopy; Free Radicals; Liver; Male; Metyrapone; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Paraquat; Pentetic Acid; Pyridinium Compounds; Rats | 1991 |
The protective effect of sulfite on menadione- and diquat-induced cytotoxicity in isolated rat hepatocytes.
Topics: Animals; Chemical and Drug Induced Liver Injury; Diquat; Glutathione; In Vitro Techniques; Inactivation, Metabolic; Liver; Male; Microsomes, Liver; Oxygen Consumption; Proteins; Pyridinium Compounds; Rats; Rats, Inbred Strains; Sulfites; Vitamin K | 1990 |
Liver membrane calcium transport in diquat-induced oxidative stress in vivo.
Topics: Animals; Biological Transport; Calcium; Cell Membrane; Cell Membrane Permeability; Chemical and Drug Induced Liver Injury; Diquat; Hydroxy Acids; In Vitro Techniques; Iron; Lipid Peroxides; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Inbred Strains | 1988 |