Page last updated: 2024-08-17

diquat and Acute Liver Injury, Drug-Induced

diquat has been researched along with Acute Liver Injury, Drug-Induced in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's4 (26.67)18.2507
2000's4 (26.67)29.6817
2010's3 (20.00)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Ekins, S; Williams, AJ; Xu, JJ1
Chen, Y; Ji, S; Jia, P; Li, Y; Wang, T; Xu, J; Zhang, H1
Chen, Y; Wang, T; Zhang, H1
He, L; Wu, C; Wu, X; Yin, Y; Zhang, Y; Zhou, X1
Farhood, A; Hong, JY; Jaeschke, H; Lebofsky, M1
Klaassen, CD; Wu, KC; Zhang, Y1
Gupta, S; Hansen, TN; Rogers, LK; Smith, CV; Welty, SE1
Alenda, C; Gutiérrez, A; Peiró, AM; Pérez-Mateo, M; Ramírez, A; Such, J; Zapater, P1
Burk, RF; Lane, JM; Lawrence, RA1
Geske, RS; Gupta, S; Husser, RC; Smith, CV; Welty, SE1
Benzick, AE; Jaeschke, H1
Donarski, WJ; Jolly, RA; Ochoa, R; Petry, TW; Wolfgang, GH1
DeGray, JA; Mason, RP; Rao, DN1
Cotgreave, IA; Lindeke, B; Moldéus, P; Sun, YP1
Hughes, H; Mitchell, JR; Smith, CV; Tsokos-Kuhn, JO1

Trials

1 trial(s) available for diquat and Acute Liver Injury, Drug-Induced

ArticleYear
Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat.
    Food & function, 2020, May-01, Volume: 11, Issue:5

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Diquat; Energy Metabolism; Gene Expression Regulation; Glutathione; Herbicides; Liver; Male; Mitochondrial Diseases; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Superoxides; Swine

2020

Other Studies

14 other study(ies) available for diquat and Acute Liver Injury, Drug-Induced

ArticleYear
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Pterostilbene as a protective antioxidant attenuates diquat-induced liver injury and oxidative stress in 21-day-old broiler chickens.
    Poultry science, 2020, Volume: 99, Issue:6

    Topics: Animal Feed; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chickens; Diet; Dietary Supplements; Diquat; Dose-Response Relationship, Drug; Herbicides; Male; Oxidative Stress; Poultry Diseases; Protective Agents; Random Allocation; Stilbenes

2020
Serine alleviates oxidative stress via supporting glutathione synthesis and methionine cycle in mice.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:11

    Topics: Animals; Antioxidants; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cycloleucine; Cystathionine beta-Synthase; Defoliants, Chemical; Dietary Supplements; Diquat; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione; Hepatocytes; Homocysteine; Male; Methionine; Methionine Adenosyltransferase; Mice, Inbred C57BL; Oxidative Stress; Random Allocation; RNA Interference; Serine; Specific Pathogen-Free Organisms

2017
Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:3

    Topics: Alanine Transaminase; Aldehydes; Animals; Antifibrinolytic Agents; Apoptosis; Caspases; Chemical and Drug Induced Liver Injury; Diquat; Disease Models, Animal; DNA Fragmentation; Endotoxins; Galactosamine; Glutathione Disulfide; Hepatocytes; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Liver Diseases; Male; Necrosis; Oxidative Stress; Rats; Rats, Inbred F344; Superoxides; Vitamin K 3

2009
Nrf2 protects against diquat-induced liver and lung injury.
    Free radical research, 2012, Volume: 46, Issue:10

    Topics: Alanine Transaminase; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Diquat; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Herbicides; Inbreeding; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Survival Analysis; Thiobarbituric Acid Reactive Substances

2012
Nuclear and nucleolar glutathione reductase, peroxidase, and transferase activities in livers of male and female Fischer-344 rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 69, Issue:1

    Topics: Animals; Blotting, Western; Cell Nucleolus; Cell Nucleus; Chemical and Drug Induced Liver Injury; Diquat; DNA; Female; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Herbicides; Liver; Male; Mice; Necrosis; Rats; Rats, Inbred F344; Reactive Oxygen Species

2002
Hepatotoxicity related to paraquat and diquat absorption through intact skin.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:11

    Topics: Aged; Biopsy; Chemical and Drug Induced Liver Injury; Cholangiopancreatography, Magnetic Resonance; Curcumin; Diquat; Enzyme Inhibitors; Follow-Up Studies; Herbicides; Humans; Male; Paraquat; Skin Absorption; Ultrasonography, Doppler

2007
Liver necrosis and lipid peroxidation in the rat as the result of paraquat and diquat administration. Effect of selenium deficiency.
    The Journal of clinical investigation, 1980, Volume: 65, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diquat; Ethane; Kidney Diseases; Lipid Peroxides; Liver Diseases; Male; Necrosis; Paraquat; Pyridinium Compounds; Rats; Selenium

1980
Sex differences in diquat-induced hepatic necrosis and DNA fragmentation in Fischer 344 rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 54, Issue:1

    Topics: Alanine Transaminase; Animals; Bile Ducts; Blotting, Western; Chemical and Drug Induced Liver Injury; Diquat; DNA Fragmentation; Electrophoresis, Polyacrylamide Gel; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Herbicides; Male; Necrosis; Proteins; Rats; Rats, Inbred F344; Sex Characteristics; Superoxide Dismutase

2000
Pathophysiological consequences of enhanced intracellular superoxide formation in isolated perfused rat liver.
    Chemico-biological interactions, 1992, Sep-14, Volume: 84, Issue:1

    Topics: Animals; Bile; Carmustine; Chemical and Drug Induced Liver Injury; Diquat; Ferrous Compounds; Glutathione; Glutathione Reductase; Ketones; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred F344; Superoxides

1992
Antioxidant-dependent inhibition of diquat-induced toxicity in vivo.
    Toxicology, 1992, Volume: 74, Issue:1

    Topics: Alanine Transaminase; Animals; Antioxidants; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Chromans; Diquat; Kidney Cortex Necrosis; Kidney Diseases; Lipid Peroxidation; Lipid Peroxides; Liver; Liver Diseases; Male; Necrosis; Peritoneal Cavity; Phenylenediamines; Piperazines; Pregnatrienes; Rats; Rats, Inbred F344; Time Factors

1992
Reduction of paraquat and related bipyridylium compounds to free radical metabolites by rat hepatocytes.
    Archives of biochemistry and biophysics, 1991, Aug-15, Volume: 289, Issue:1

    Topics: Animals; Benzyl Viologen; Cations; Chemical and Drug Induced Liver Injury; Cobalt; Cytochrome P-450 Enzyme System; Diquat; Electron Spin Resonance Spectroscopy; Free Radicals; Liver; Male; Metyrapone; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Paraquat; Pentetic Acid; Pyridinium Compounds; Rats

1991
The protective effect of sulfite on menadione- and diquat-induced cytotoxicity in isolated rat hepatocytes.
    Pharmacology & toxicology, 1990, Volume: 66, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Diquat; Glutathione; In Vitro Techniques; Inactivation, Metabolic; Liver; Male; Microsomes, Liver; Oxygen Consumption; Proteins; Pyridinium Compounds; Rats; Rats, Inbred Strains; Sulfites; Vitamin K

1990
Liver membrane calcium transport in diquat-induced oxidative stress in vivo.
    Molecular pharmacology, 1988, Volume: 34, Issue:2

    Topics: Animals; Biological Transport; Calcium; Cell Membrane; Cell Membrane Permeability; Chemical and Drug Induced Liver Injury; Diquat; Hydroxy Acids; In Vitro Techniques; Iron; Lipid Peroxides; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Pyridinium Compounds; Rats; Rats, Inbred Strains

1988