dipyrromethene has been researched along with Melanoma* in 2 studies
2 other study(ies) available for dipyrromethene and Melanoma
| Article | Year |
|---|---|
Photodynamic treatment of melanoma cells using aza-dipyrromethenes as photosensitizers.
In this study, we report for the first time the use of four aza-dipyrromethenes (ADPMs) as photosensitizers for cancer PDT. The synthesis and characterization of the ADPMs and their photodynamic action against B16F10 melanoma cells were assessed. ADPM 2 is the best singlet oxygen generator and the most phototoxic (at 2.5 μM) towards B16F10 cells. Topics: Animals; Antineoplastic Agents; Aza Compounds; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Melanoma; Mice; Molecular Structure; Photochemotherapy; Photosensitizing Agents; Porphobilinogen; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Synthesis and melanogenesis evaluation of 3',4',7-trihydroxyflavanone derivatives and characterization of flavanone-BODIPY.
A class of flavanone was found to improve melanogenesis in B16F10 mouse melanoma cell line, but little is known about its target. Herein we described the synthesis and bioevaluation of sixteen 3',4',7-trihydroxyflavanone analogues and further synthesized a novel fluorescent flavanone-BODIPY, which could improve melanogenesis in B16F10 cell line by selectively binding to its endoplasmic reticulum. The fluorescent flavanone-BODIPY was proved to be a valuable probe for studying the localization of intracellular flavanone on living cells. Topics: Animals; Boron Compounds; Cell Line, Tumor; Endoplasmic Reticulum; Flavanones; Fluorescent Dyes; Melanoma; Mice; Mice, Inbred C57BL; Porphobilinogen | 2015 |