dipyrone has been researched along with Allodynia in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbosa, FL; Hughes, DL; Rüdiger, AL; Salvador, MJ; Soares, AS; Stefanello, MÉA; Zampronio, AR | 1 |
| Bassani da Silva, B; Fernandes Magalhães, S; Gonçalves Dos Santos, G; Parada, CA; Tambeli, CH; Vendramini, PH; Vieira, WF | 1 |
| Antoniazzi, CT; Dalenogare, DP; de Almeida, AS; Ferreira, J; Fialho, MFP; Kudsi, SQ; Lückemeyer, DD; Oliveira, SM; Pereira, GC; Pereira, VL; Ritter, C; Trevisan, G | 1 |
| Kwiatkowski, K; Makuch, W; Mika, J; Pawlik, K; Piotrowska, A; Rojewska, E; Wordliczek, J; Zajaczkowska, R | 1 |
| Benemei, S; Chiarugi, A; Coppi, E; De Logu, F; Fusi, C; Geppetti, P; Marone, IM; Materazzi, S; Nassini, R; Patacchini, R; Preti, D; Tonello, R; Tuccinardi, T | 1 |
| Diniz, MS; Souza, VL; Steagall, PV; Teixeira, LR; Teixeira-Neto, FJ; Thomazini, CM; Zanuzzo, FS | 1 |
| Casagrande, R; Fattori, V; Manchope, MF; Mizokami, SS; Pinho-Ribeiro, FA; Verri, WA; Zarpelon, AC | 1 |
| Castor, MG; Duarte, ID; Navarro, LC; Romero, TR; Silva, LC | 1 |
| Benito, J; Canfrán, S; Gómez de Segura, IA; Largo, C; Polo, G; Ruiz-Pérez, D | 1 |
| Araiza-Saldaña, CI; Baños-González, MA; Castañeda-Corral, G; Guzmán-Priego, CG; Méndez-Mena, R; Torres-López, JE | 1 |
| Avila, C; Escobar, W; Limongi, R; Ramirez, K; Vanegas, H; Vazquez, E | 1 |
| Escobar, W; Ramirez, K; Vanegas, H; Vazquez, E | 1 |
| Bakhle, YS; dos Reis, WG; França, DS; Francischi, JN; Menezes, GB; Rezende, RM | 1 |
| Devissaguet, M; Ferreira, SH; Lesieur, D; Lorenzetti, BB; Tsouderos, Y | 1 |
| Carvalho, WM; Ferreira, SH; Francischi, JN; Miranda, AE; Silva, CV; Tatsuo, MA | 1 |
| Beirith, A; Calixto, JB; Creczynski-Pasa, TB; Rodrigues, AL; Santos, AR | 1 |
| De Campos, DI; Ferreira, SH; Lorenzetti, BB | 1 |
| Krushkov, I; Vlaskovska, M | 1 |
| Ferreira, SH; Lorenzetti, BB | 1 |
| Cunha, FQ; de Campos, DI; Ferreira, SH | 1 |
1 trial(s) available for dipyrone and Allodynia
| Article | Year |
|---|---|
Analgesic and antihyperalgesic effects of dipyrone, meloxicam or a dipyrone-meloxicam combination in bitches undergoing ovariohysterectomy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dogs; Double-Blind Method; Drug Therapy, Combination; Female; Hyperalgesia; Hysterectomy; Meloxicam; Ovariectomy; Pain, Postoperative; Thiazines; Thiazoles | 2015 |
19 other study(ies) available for dipyrone and Allodynia
| Article | Year |
|---|---|
Naphthoquinones of Sinningia reitzii and Anti-inflammatory/Antinociceptive Activities of 8-Hydroxydehydrodunnione.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Dinoprostone; Edema; Hyperalgesia; Magnoliopsida; Mice; Molecular Structure; Naphthoquinones; Plant Tubers | 2017 |
Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Carrageenan; Dipyrone; Hydrolysis; Hyperalgesia; Indoles; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Opioid, kappa; Somatostatin | 2020 |
Nociception in a Progressive Multiple Sclerosis Model in Mice Is Dependent on Spinal TRPA1 Channel Activation.
Topics: Acetanilides; Acetophenones; Analgesics; Animals; Antipyrine; Dipyrone; Encephalomyelitis, Autoimmune, Experimental; Female; Hyperalgesia; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; NADPH Oxidases; Nerve Tissue Proteins; Neuralgia; Nociception; Oligonucleotides, Antisense; Oxidative Stress; Oximes; Peptide Fragments; Pregabalin; Purines; Spinal Cord; Thioctic Acid; TRPA1 Cation Channel; Up-Regulation | 2020 |
Metamizole relieves pain by influencing cytokine levels in dorsal root ganglia in a rat model of neuropathic pain.
Topics: Analgesia; Animals; Cytokines; Dipyrone; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Male; Neuralgia; Nociception; Peripheral Nerve Injuries; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy; Spinal Cord | 2020 |
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives.
Topics: Analgesics; Animals; Calcium Channels; Dipyrone; HEK293 Cells; Humans; Hyperalgesia; Male; Mice, Inbred C57BL; Nerve Tissue Proteins; Nociception; Pain; Pyrazolones; Rats, Sprague-Dawley; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPC Cation Channels | 2015 |
Naringenin reduces inflammatory pain in mice.
Topics: Analgesics; Animals; Cytokines; Dipyrone; Disease Models, Animal; Dose-Response Relationship, Drug; Flavanones; Hyperalgesia; Indomethacin; Injections, Intraperitoneal; KATP Channels; Liver; Male; Mice; Motor Activity; Neutrophils; NF-kappa B; Nociceptors; Stomach; Visceral Pain | 2016 |
κ-Opioid receptor participates of NSAIDs peripheral antinociception.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Dipyrone; Hindlimb; Hyperalgesia; Male; Naloxone; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2016 |
Metamizole (dipyrone) effects on sevoflurane requirements and postoperative hyperalgesia in rats.
Topics: Animals; Dipyrone; Hyperalgesia; Male; Methyl Ethers; Nociception; Pain Threshold; Prospective Studies; Pulmonary Alveoli; Random Allocation; Rats; Rats, Wistar; Sevoflurane | 2017 |
Antihyperalgesic Effects of Indomethacin, Ketorolac, and Metamizole in Rats: Effects of Metformin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dipyrone; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Hyperalgesia; Indomethacin; Ketorolac; Male; Metformin; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2017 |
Metamizol, a non-opioid analgesic, acts via endocannabinoids in the PAG-RVM axis during inflammation in rats.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cannabinoid Receptor Modulators; Dipyrone; Endocannabinoids; Hyperalgesia; Inflammation; Male; Medulla Oblongata; Microinjections; Neurons; Nociceptors; Pain Measurement; Periaqueductal Gray; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1 | 2012 |
A nonopioid analgesic acts upon the PAG-RVM axis to reverse inflammatory hyperalgesia.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Extremities; Hyperalgesia; Inflammation; Laminectomy; Male; Medulla Oblongata; Microinjections; Neurons, Afferent; Pain Measurement; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Spinal Cord | 2007 |
Different mechanisms underlie the analgesic actions of paracetamol and dipyrone in a rat model of inflammatory pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carrageenan; Dipyrone; Disease Models, Animal; Hyperalgesia; Inflammation; Injections, Intralesional; Injections, Subcutaneous; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Rats, Wistar; Research Design; Time Factors | 2008 |
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hyperalgesia; Indomethacin; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar; Thiazoles; Yohimbine | 1995 |
Analgesic and antiinflammatory effects of dipyrone in rat adjuvant arthritis model.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chronic Disease; Dexamethasone; Dipyrone; Dose-Response Relationship, Drug; Edema; Female; Hyperalgesia; Indomethacin; Rats; Rats, Inbred Strains | 1994 |
Spinal and supraspinal antinociceptive action of dipyrone in formalin, capsaicin and glutamate tests. Study of the mechanism of action.
Topics: Analgesics, Non-Narcotic; Animals; Capsaicin; Dipyrone; Enzyme Inhibitors; Formaldehyde; Glutamic Acid; Hyperalgesia; Male; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain; Pain Measurement; Postural Balance; Psychomotor Performance; Rats; Rats, Wistar; Reaction Time; Spinal Cord | 1998 |
Induction, blockade and restoration of a persistent hypersensitive state.
Topics: Animals; Bucladesine; Chronic Disease; Dipyrone; Dopamine; Hyperalgesia; Male; Prostaglandins E; Rats; Rats, Inbred Strains | 1990 |
[Study of the effect of analgeton on the release of beta-endorphin and its effect on chronic hyperalgesia].
Topics: Aminopyrine; Animals; beta-Endorphin; Chronic Disease; Dipyrone; Drug Combinations; Hyperalgesia; Hyperesthesia; Male; Pain, Intractable; Picolines; Rats; Rats, Inbred Strains | 1989 |
Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Bucladesine; Carrageenan; Dinoprostone; Dipyrone; Edema; Hyperalgesia; Hyperesthesia; Indomethacin; Isoproterenol; Male; Prostaglandins E; Rats; Rats, Inbred Strains | 1985 |
A new mechanism of action of dipyrone: blockade of the release of a nociceptive factor from macrophages.
Topics: Aminopyrine; Animals; Dipyrone; Escherichia coli; Hyperalgesia; Indomethacin; Macrophages; Mice; Nociceptors; Rats; Seizures | 1988 |