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dipyridamole and Trypanosomiasis, African

dipyridamole has been researched along with Trypanosomiasis, African in 1 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bland, ND1
Wang, C1
Tallman, C1
Gustafson, AE1
Wang, Z1
Ashton, TD1
Ochiana, SO1
McAllister, G1
Cotter, K1
Fang, AP1
Gechijian, L1
Garceau, N1
Gangurde, R1
Ortenberg, R1
Ondrechen, MJ1
Campbell, RK1
Pollastri, MP1

Other Studies

1 other study available for dipyridamole and Trypanosomiasis, African

ArticleYear
Pharmacological validation of Trypanosoma brucei phosphodiesterases B1 and B2 as druggable targets for African sleeping sickness.
    Journal of medicinal chemistry, 2011, Dec-08, Volume: 54, Issue:23

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Benzamides; Catalytic Domain; Humans; Models, Molecular; Molecu

2011