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dipyridamole and Thrombopenia

dipyridamole has been researched along with Thrombopenia in 24 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"Three children with the hemolytic-uremic syndrome were treated with heparin, aspirin, and dipyridamole."7.65Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole. ( Arenson, EB; August, CS, 1975)
"Thromboxane B2 production was slightly increased."5.27Failure of two anti-platelet drugs (indobufen and dipyridamole) to improve thrombocytopenia in liver cirrhosis. ( Fabris, F; Gerunda, GE; Girolami, A; Luzzatto, G; Zangrandi, F, 1987)
"A 23-year-old woman developed ischemic stroke (IS) 8 to 12 hours after ingestion of sumatriptan (ST) and then developed mucosal bleeding secondary to acute thrombocytopenia likely due to dipyridamole (DP) on the 10th day poststroke."4.87Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy. ( Adams, C; Ames, PR; Dhirendra, A, 2011)
" Oral administration of ticlopidine inhibited the transient thrombocytopenia caused by ADP."3.66Inhibition of thrombocytopenic episodes caused by the Arthus reaction, the sub-lethal Forssman reaction and ADP. ( Butler, KD; White, AM, 1980)
" It appears that the diagnostic tests most likely to aid in diagnosis and to reliably inform the clinician when the intravascular clotting process has been stopped are those that determine the antithrombin-III level, the presence of soluble fibrin monomer, and the finding of elevated fibrin(ogen) degradation products, thrombocytopenia and a prolonged thrombin time in the face of the appropriate type of bleeding in the appropriate clinical setting."3.66Disseminated intravascular coagulation: a clinical/laboratory study of 48 patients. ( Bick, RL, 1981)
"Three children with the hemolytic-uremic syndrome were treated with heparin, aspirin, and dipyridamole."3.65Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole. ( Arenson, EB; August, CS, 1975)
"Thromboxane B2 production was slightly increased."1.27Failure of two anti-platelet drugs (indobufen and dipyridamole) to improve thrombocytopenia in liver cirrhosis. ( Fabris, F; Gerunda, GE; Girolami, A; Luzzatto, G; Zangrandi, F, 1987)
"Dipyridamole and ancrod pretreatment did not influence the decrease of platelets and their accumulation in the lung after tumour cell injection."1.25The role of blood platelets in experimental metastases. ( Hilgard, P, 1973)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199021 (87.50)18.7374
1990's1 (4.17)18.2507
2000's0 (0.00)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, C1
Dhirendra, A1
Ames, PR1
Granat, F1
Geffré, A1
Braun, JP1
Trumel, C1
Kelton, JG1
Hirsh, J1
Butler, KD1
White, AM1
Bick, RL1
Fong, JS1
de Chadarevian, JP1
Kaplan, BS1
Chong, BH2
Grace, CS1
Rozenberg, MC1
Friedman, RJ1
Burns, ER1
Nuutinen, LS1
Pihlajaniemi, R1
Saarela, E1
Kärkölä, P1
Hollmén, A1
Mlczoch, J1
Weir, EK1
Grover, RF1
Zacharski, LR1
Lusted, D1
Glick, JL1
de Gaetano, G1
Donati, MB1
Garattini, S1
Arenson, EB1
August, CS1
Gruel, Y1
Lermusiaux, P1
Lang, M1
Darnige, L1
Rupin, A1
Delahousse, B1
Guilmot, JL1
Leroy, J1
Luzzatto, G2
Fabris, F2
Gerunda, GE2
Zangrandi, F1
Girolami, A2
Holdrinet, RS1
Namdar, Z1
Haanen, C1
Makhoul, RG1
McCann, RL1
Austin, EH1
Greenberg, CS1
Lowe, JE1
De Franchis, G1
Castaldi, PA1
Hilgard, P1
Kreiskott, H1
Hofmann, HP1
Becker, RM1
Smith, MR1
Dobell, AR1
Braun, L1
Braun, I1
Hockerts, T1
Byrne, JJ1
Migliore, JJ1
Beekley, W1
Guardione, VA1
Williams, LF1

Reviews

4 reviews available for dipyridamole and Thrombopenia

ArticleYear
Ischemic stroke followed by acute thrombocytopenia: a double iatrogenic whammy.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2011, Volume: 17, Issue:1

    Topics: Acute Disease; Adult; Brain Ischemia; Dipyridamole; Female; Hemorrhage; Humans; Iatrogenic Disease;

2011
Bleeding associated with antithrombotic therapy.
    Seminars in hematology, 1980, Volume: 17, Issue:4

    Topics: 4-Hydroxycoumarins; Aspirin; Dextrans; Dipyridamole; Dose-Response Relationship, Drug; Fibrinolytic

1980
Hemolytic-uremic syndrome. Current concepts and management.
    Pediatric clinics of North America, 1982, Volume: 29, Issue:4

    Topics: Anemia, Hemolytic; Blood Transfusion; Child; Child, Preschool; Dipyridamole; Epoprostenol; Follow-Up

1982
Role of platelets in the proliferative response of the injured artery.
    Progress in hemostasis and thrombosis, 1978, Volume: 4

    Topics: Animals; Arteries; Arteriosclerosis; Blood Platelets; Cell Differentiation; Cell Survival; Dipyridam

1978

Other Studies

20 other studies available for dipyridamole and Thrombopenia

ArticleYear
Comparison of platelet clumping and complete blood count results with Sysmex XT-2000iV in feline blood sampled on EDTA or EDTA plus CTAD (citrate, theophylline, adenosine and dipyridamole).
    Journal of feline medicine and surgery, 2011, Volume: 13, Issue:12

    Topics: Adenosine; Animals; Blood Cell Count; Cat Diseases; Cats; Citric Acid; Dipyridamole; Edetic Acid; Fl

2011
Inhibition of thrombocytopenic episodes caused by the Arthus reaction, the sub-lethal Forssman reaction and ADP.
    Artery, 1980, Volume: 8, Issue:5

    Topics: Adenosine Diphosphate; Animals; Antibodies; Arthus Reaction; Aspirin; Dipyridamole; Forssman Antigen

1980
Disseminated intravascular coagulation: a clinical/laboratory study of 48 patients.
    Annals of the New York Academy of Sciences, 1981, Volume: 370

    Topics: Acute Disease; Afibrinogenemia; Antacids; Antithrombin III; Chronic Disease; Dipyridamole; Dissemina

1981
Heparin-induced thrombocytopenia: effect of heparin platelet antibody on platelets.
    British journal of haematology, 1981, Volume: 49, Issue:4

    Topics: Adenosine Diphosphate; Adult; Antibodies; Aspirin; Blood Platelets; Complement Fixation Tests; Dipyr

1981
The effect of dipyridamole on the thrombocyte count and bleeding tendency in open-heart surgery.
    The Journal of thoracic and cardiovascular surgery, 1977, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Blood Cell Count; Blood Coagulation; Blood Platelets; Cardiopulmonary Bypass; Dip

1977
Inhibition of hypoxic pulmonary vasoconstriction by dipyridamole is not platelet mediated.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3

    Topics: Animals; Blood Platelets; Blood Pressure; Dipyridamole; Dogs; Female; Hypoxia; Immune Sera; Lung; Ma

1977
Thrombotic thrombocytopenic purpura in a previously splenectomized patient.
    The American journal of medicine, 1976, Volume: 60, Issue:7

    Topics: Adult; Aspirin; Dipyridamole; Humans; Male; Prednisone; Spleen; Splenectomy; Thrombocytopenia

1976
Drugs affecting platelet function tests: their effects on haemostasis and surgical bleeding.
    Thrombosis et diathesis haemorrhagica, 1975, Sep-30, Volume: 34, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Coagulation Disorders; Blood Donors; Blood P

1975
Preliminary report: treatment of the hemolytic-uremic syndrome with aspirin and dipyridamole.
    The Journal of pediatrics, 1975, Volume: 86, Issue:6

    Topics: Acute Disease; Anemia, Hemolytic; Aspirin; Blood Platelet Disorders; Blood Platelets; Blood Transfus

1975
Usefulness of antiplatelet drugs in the management of heparin-associated thrombocytopenia and thrombosis.
    Annals of vascular surgery, 1991, Volume: 5, Issue:6

    Topics: Aged; Aorta, Abdominal; Aspirin; Dipyridamole; Female; Femoral Vein; Heparin; Humans; Iliac Artery;

1991
Failure of two anti-platelet drugs (indobufen and dipyridamole) to improve thrombocytopenia in liver cirrhosis.
    Acta haematologica, 1987, Volume: 77, Issue:2

    Topics: Aged; beta-Thromboglobulin; Blood Platelets; Dipyridamole; Female; Humans; Isoindoles; Liver Cirrhos

1987
Thrombotic thrombocytopenic purpura: clinical course and response to therapy in twelve patients.
    The Netherlands journal of medicine, 1988, Volume: 33, Issue:3-4

    Topics: Adolescent; Adult; Anemia, Hemolytic; Combined Modality Therapy; Dipyridamole; Female; Humans; Male;

1988
Management of patients with heparin-associated thrombocytopenia and thrombosis requiring cardiac surgery.
    The Annals of thoracic surgery, 1987, Volume: 43, Issue:6

    Topics: Adult; Aged; Aspirin; Cardiopulmonary Bypass; Coronary Artery Bypass; Dipyridamole; Emergencies; Fem

1987
Full dose dipyridamole significantly improves thrombocytopenia in liver cirrhosis.
    Blut, 1987, Volume: 55, Issue:1

    Topics: Adult; Aged; Dipyridamole; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Platelet Count; Throm

1987
Heparin-induced thrombocytopenia: further studies of the effects of heparin-dependent antibodies on platelets.
    British journal of haematology, 1986, Volume: 64, Issue:2

    Topics: Adenosine Diphosphate; Antibodies; Aspirin; Bernard-Soulier Syndrome; Dipyridamole; Heparin; Humans;

1986
The role of blood platelets in experimental metastases.
    British journal of cancer, 1973, Volume: 28, Issue:5

    Topics: Animals; Blood Cell Count; Blood Platelets; Carcinoma 256, Walker; Chromium; Chromium Isotopes; Dipy

1973
[Animal experiment studies on the inhibition of platelet aggregation by verapamil in vitro and in vivo].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:11

    Topics: Adenosine Diphosphate; Animals; Aspirin; Depression, Chemical; Dipyridamole; Dogs; Fatty Acids; Huma

1973
Effect of platelet inhibition on platelet phenomena in cardiopulmonary bypass in pigs.
    Annals of surgery, 1974, Volume: 179, Issue:1

    Topics: Animals; Blood Cell Count; Blood Flow Velocity; Blood Platelets; Carbon Dioxide; Dipyridamole; Extra

1974
The pharmacological influence on thrombocyte aggregation in the extracorporeal circulation of dogs.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1971, Volume: 3, Issue:5

    Topics: Animals; Blood Cell Count; Depression, Chemical; Dipyridamole; Dogs; Extracorporeal Circulation; Hem

1971
Platelet response to induction of hemorrhagic pancreatitis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Aspirin; Blood Cell Count; Dipyridamole; Disease Models, Animal; Dog

1971